Differentiation of white and brown adipocyte (Homo sapiens)

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Description

Development of white versus brown adipocytes (figure from Handbook of Obesity). Transcription factors and nuclear regulators controlling the development of white versus brown adipocytes are shown in the pathway. At the bottom a selection of identified markers of white and brown adipocytes were added (from Nascimento et al).

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Quality Tags

Ontology Terms

 

Bibliography

  1. Nascimento EB, Boon MR, van Marken Lichtenbelt WD; ''Fat cells gain new identities.''; Sci Transl Med, 2014 PubMed Europe PMC Scholia
  2. George A. Bray, Claude Bouchard; ''Handbook of Obesity (3rd edition)''; CRC Press, 2014

History

View all...
CompareRevisionActionTimeUserComment
141349view02:57, 11 November 2025EweitzUse gene symbols
141348view02:43, 11 November 2025EweitzOntology Term : 'preadipocyte' added !
141347view02:43, 11 November 2025EweitzOntology Term : 'white adipocyte' added !
141346view02:41, 11 November 2025EweitzOntology Term : 'brown adipocyte' added !
141345view02:41, 11 November 2025EweitzStandardize case
141344view02:40, 11 November 2025EweitzEconomize layout
118446view14:50, 27 May 2021Marvin M2added isbn
116469view10:09, 7 May 2021EweitzModified title
87889view12:47, 25 July 2016SusanOntology Term : 'regulatory pathway' added !
79216view10:41, 13 March 2015EgonwAdded GraphId's to a number of DataNode's which didn't have one.
78904view15:40, 11 February 2015MkutmonModified description
78903view15:39, 11 February 2015MkutmonModified description
78902view15:38, 11 February 2015MkutmonModified description
78901view15:27, 11 February 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADIPOQGeneProductENSG00000181092 (Ensembl) "Adiponectin" originally
BMP2GeneProductENSG00000125845 (Ensembl)
BMP4GeneProductENSG00000125378 (Ensembl)
BMP7GeneProductENSG00000101144 (Ensembl)
CEBPAGeneProductENSG00000245848 (Ensembl) "C/EBPα" originally
CEBPBGeneProductENSG00000172216 (Ensembl) "C/EBPβ" originally
CEBPGGeneProductENSG00000153879 (Ensembl) "C/EBPδ" originally
CIDEAGeneProductENSG00000176194 (Ensembl)
EBF3GeneProductENSG00000108001 (Ensembl)
EVA1GeneProductENSG00000149573 (Ensembl)
HOXC8GeneProductENSG00000037965 (Ensembl)
HOXC9GeneProductENSG00000180806 (Ensembl)
HSPB7GeneProductENSG00000173641 (Ensembl)
LEPGeneProductENSG00000174697 (Ensembl) "Leptin" originally
PLAC8GeneProductENSG00000145287 (Ensembl)
PPARGC1AGeneProductENSG00000109819 (Ensembl) "PGC-1α" originally
PPARGC1BGeneProductENSG00000155846 (Ensembl) "PGC-1β" originally
PPARGGeneProductENSG00000132170 (Ensembl) "PPARγ" originally
PRDM16GeneProductENSG00000142611 (Ensembl)
SLC7A10GeneProductENSG00000130876 (Ensembl) "ASC-1" originally
SMAD1GeneProductENSG00000170365 (Ensembl)
SMAD5GeneProductENSG00000113658 (Ensembl)
SMAD9GeneProductENSG00000120693 (Ensembl)
ZIC1GeneProductENSG00000152977 (Ensembl)
ZNF423GeneProductENSG00000102935 (Ensembl) "Zfp423" originally

Annotated Interactions

No annotated interactions

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