Methionine salvage pathway (Oryza sativa)

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cytosolH2OH2O5'-methylthioadenosine1-aminocyclopropane-1-carboxylatea standard alphaamino acidH2OPPiS-adenosylmethioninesynthetasesS-methyl-5-thioribosekinaseATPPiADPa keto acidL-Met5-methylthioribose5-methylthioribose-1-phosphateH2OAdoMetaminocyclopropanecarboxylatesynthetaseAdeHCOOH5-(methylthio)-2,3-dioxopentylphosphate5-methylthioribulose-1-phosphatemethylthioribose-1-phosphateisomerase(LOC_OS11G11050.1)2-oxo-4-methylthiobutanoateATPO2PiMTA/SAH nucleosidase(LOC_OS06G02220.1)


Description

Developed by Gramene.org Source:Plant Reactome.

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Ontology Terms

 

Bibliography

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History

CompareRevisionActionTimeUserComment
123829view12:18, 16 August 2022EgonwOntology Term : 'classic metabolic pathway' added !
118103view10:54, 24 May 2021EweitzModified title
81997view14:39, 8 September 2015Anweshafixing title, data source, & tagging incomplete pathways
80500view14:48, 25 June 2015AnweshaNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
Metabolite
1-aminocyclopropane-1-carboxylateMetaboliteCHEBI:18053 (ChEBI)
2-oxo-4-methylthiobutanoateMetaboliteCHEBI:33574 (ChEBI)
5'-methylthioadenosineMetaboliteCHEBI:17509 (ChEBI)
5-(methylthio)-2,3-dioxopentyl phosphateMetaboliteCHEBI:50604 (ChEBI)
5-methylthioribose-1-phosphateMetaboliteCHEBI:27859 (ChEBI)
5-methylthioriboseMetaboliteCHEBI:16895 (ChEBI)
5-methylthioribulose-1-phosphateMetaboliteCHEBI:28096 (ChEBI)
ADPMetaboliteCHEBI:16761 (ChEBI)
ATPMetaboliteCHEBI:15422 (ChEBI)
AdeMetaboliteCHEBI:16708 (ChEBI)
AdoMetMetaboliteCHEBI:15414 (ChEBI)
H2OMetaboliteCHEBI:15377 (ChEBI)
HCOOHMetaboliteCHEBI:30751 (ChEBI)
L-MetMetaboliteCHEBI:16643 (ChEBI)
MTA/SAH nucleosidase (LOC_OS06G02220.1)ProteinQ9LHZ0 (Uniprot-TrEMBL) Catalyzes the conversion of 5'-methylthioadenosine into 5-methylthioribose.
O2MetaboliteCHEBI:15379 (ChEBI)
PPiMetaboliteCHEBI:29888 (ChEBI)
PiMetaboliteCHEBI:18367 (ChEBI)
S-adenosylmethionine synthetasesProtein1122222 (Reactome) Converts L-methionine into S-adenosyl-L-methionine.
S-methyl-5-thioribose kinaseProtein1121756 (Reactome) Catalyzes the conversion of 5-methylthioribose into 5-methylthioribose-1-phosphate.
a keto acidMetaboliteCHEBI:35903 (ChEBI)
a standard alpha amino acidMetaboliteCHEBI:33704 (ChEBI)
aminocyclopropane

carboxylate

synthetase		Protein1121926 (Reactome) 1-amino cyclopropane-1carboxylate synthetase defined set. Catalyses the reaction: S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine
methylthioribose-1-phosphate

isomerase

(LOC_OS11G11050.1)		ProteinQ0ITU1 (Uniprot-TrEMBL)

Annotated Interactions

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SourceTargetTypeDatabase referenceComment
1-aminocyclopropane-1-carboxylateArrow1120391 (Reactome)
1119643 (Reactome)
1119805 (Reactome) 5-methylthioribose is converted into 5-methylthioribose-1-phosphate by enzymatic activity of S-methyl-5-thioribose kinase.
1120391 (Reactome) Cytosolic 1-amino cyclopropane-1 carboxylate synthetase catalyses the reaction of S-adenosyl-L-methionine to form 1-aminocyclopropane-1-carboxylate and methylthioadenosine.
1120532 (Reactome)
1120565 (Reactome)
1120834 (Reactome) 5-methylthioribose-1-phosphate is converted into 5-methylthioribulose-1-phosphate by enzymatic activity of an unknown gene product.
1121586 (Reactome) 2-oxo-4-methylthiobutanoate is converted into L-methionine by enzymatic activity of an unknown gene product.
1121647 (Reactome) Cytosolic S-adenosyl methionine synthetase catalyzes the reaction of ATP, L-methionine, and H2O to form phosphate, diphosphate, and S-adenosyl-L-methionine.
1121672 (Reactome)
1121676 (Reactome) 5'-methylthioadenosine is converted into 5-methylthioribose by enzymatic activity of methylthioadenosine nucleosidase.
2-oxo-4-methylthiobutanoate1121586 (Reactome)
2-oxo-4-methylthiobutanoateArrow1119643 (Reactome)
5'-methylthioadenosine1121676 (Reactome)
5'-methylthioadenosineArrow1120391 (Reactome)
5-(methylthio)-2,3-dioxopentyl phosphate1120565 (Reactome)
5-(methylthio)-2,3-dioxopentyl phosphateArrow1120532 (Reactome)
5-methylthioribose-1-phosphate1120834 (Reactome)
5-methylthioribose-1-phosphateArrow1119805 (Reactome)
5-methylthioribose1119805 (Reactome)
5-methylthioriboseArrow1121676 (Reactome)
5-methylthioribulose-1-phosphate1120532 (Reactome)
5-methylthioribulose-1-phosphateArrow1120834 (Reactome)
ADPArrow1119805 (Reactome)
ATP1119805 (Reactome)
ATP1121647 (Reactome)
AdeArrow1121676 (Reactome)
AdoMet1120391 (Reactome)
AdoMetArrow1121647 (Reactome)
Arrow1120565 (Reactome)
Arrow1121672 (Reactome)
H2O1121647 (Reactome)
H2O1121672 (Reactome)
H2O1121676 (Reactome)
H2OArrow1120532 (Reactome)
HCOOHArrow1119643 (Reactome)
L-Met1121647 (Reactome)
L-MetArrow1121586 (Reactome)
MTA/SAH nucleosidase (LOC_OS06G02220.1)mim-catalysis1121676 (Reactome)
O21119643 (Reactome)
PPiArrow1121647 (Reactome)
PiArrow1121647 (Reactome)
PiArrow1121672 (Reactome)
S-adenosylmethionine synthetasesmim-catalysis1121647 (Reactome)
S-methyl-5-thioribose kinasemim-catalysis1119805 (Reactome)
a keto acidArrow1121586 (Reactome)
a standard alpha amino acid1121586 (Reactome)
aminocyclopropane

carboxylate

synthetase		mim-catalysis1120391 (Reactome)
methylthioribose-1-phosphate

isomerase

(LOC_OS11G11050.1)		mim-catalysis1120834 (Reactome)
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