Sulindac metabolic pathway (Bos taurus)
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MSRB2
CYP1B1
MSRA
FMO
Sulindac-S
Sulfindac sulfide
Sulindac-R
Sulindac sulfone
MSRB3
CYP1A2
CYP1A2
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP2542(70621)
with a 85.0% conversion rate.
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Bibliography
Brunell D, Sagher D, Kesaraju S, Brot N, Weissbach H; ''Studies on the metabolism and biological activity of the epimers of sulindac.''; Drug Metab Dispos, 2011
PubMed
Europe PMC
Scholia
History
Compare
Revision
Action
Time
User
Comment
117617
view
11:41, 21 May 2021
Eweitz
Modified title
97757
view
13:18, 7 June 2018
Mick Eikelhof
Modified description
87598
view
08:13, 25 July 2016
MirellaKalafati
Ontology Term : 'classic metabolic pathway' added !
80713
view
15:23, 30 June 2015
Mkutmon
New pathway
External references
DataNodes
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Name
Type
Database reference
Comment
CYP1A2
GeneProduct
ENSBTAG00000000085 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000140505
CYP1B1
GeneProduct
ENSBTAG00000010531 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138061
FMO
GeneProduct
MSRA
GeneProduct
ENSBTAG00000021632 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000175806
MSRB2
GeneProduct
ENSBTAG00000044112 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000148450
MSRB3
GeneProduct
ENSBTAG00000044017 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000174099
Sulfindac sulfide
Metabolite
4509492 (Chemspider)
Sulindac sulfone
Metabolite
4582441 (Chemspider)
The structure for the sulfone in the paper is inconsistent with the entries in ChemSpider and PubChem; I assume the paper made typographic errors.
Sulindac-R
Metabolite
16046677 (PubChem-compound)
Sulindac-S
Metabolite
11245227 (PubChem-compound)
Annotated Interactions
No annotated interactions
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