Diclofenac metabolic pathway (Bos taurus)

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Annotate nodes Comment: 2 out of 12 DataNodes have a missing external reference. Check DataNode table at the bottom of the page. Please help improve this pathway by annotating gene, protein and metabolite nodes.

Approved version The current version of this pathway was approved for data analysis by Martina Kutmon.

Homology Converted Comment: Inferred from another species Revision {{{tag_revision}}} of this pathway has been inferred from another species (tagged by Maintenance bot). Expression error: Unrecognised punctuation character "{"

Ontology Terms

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Bibliography

1. Bort R, Macé K, Boobis A, Gómez-Lechón MJ, Pfeifer A, Castell J; ''Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways.''; Biochem Pharmacol, 1999 PubMed Europe PMC Scholia

History

External references

DataNodes

Name	Type	Database reference	Comment
3'-Hydroxydiclofenac	Metabolite	112230 (PubChem-compound)
4',5-Dihydroxydiclofenac	Metabolite	3052567 (PubChem-compound)
4'-hydroxydiclofenac	Metabolite	116545 (PubChem-compound)
5-hydroxydiclofenac	Metabolite	3052566 (PubChem-compound)
CYP2B6	Protein	ENSBTAG00000003871 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P20813
CYP2C18	Protein	ENSBTAG00000020375 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P33260
CYP2C19	Protein	ENSBTAG00000020375 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P33261
CYP2C8	Protein	ENSBTAG00000020375 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P10632
CYP2C9	Protein
Metabolite	Metabolite	10065052 (PubChem-compound)
diclofenac	Metabolite	3033 (PubChem-compound)

Annotated Interactions