Biogenic amine synthesis (Bos taurus)

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1Synthesis pathways for biogenic aminesfollow solid arrows through enzymatic steps,while degradation steps follow dashed arrows.DDCPAHDDCGAD1ACHEGlutamateTyrosineAcetylserotoninAANATPhenylalanineAcetylcholineMelatoninHistidineSerotoninEpinephrineTPH1CHATCholineMAOATHDDCDopamineHDCHistamineGABACOMTL-DOPATryptophanGAD2PNMTNorepinephrineDBHMAOA5-hydroxy-tryptophanASMT


Description

Biogenic amines are one of two broad classes of classical neurotransmitters (the other being amino acids) and include: acetylcholine, serotonin, histamine, and the catecholamines epinephrine, norepinephrine, and dopamine. Source: http://www.whatislife.com/reader2/Metabolism/pathway/Neurotransmitter.html

Comments

GenMAPP remarks 
reference web site at end of Notes
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP550(73391) with a 100.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Purves, Dale, Augustine, George J., Fitzpatrick, David, Katz, Lawrence C., LaMantia, Anthony-Samuel, McNamara, James O., Williams, S. Mark.; ''Neuroscience''; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=neurosci&part=A405, 2001

History

CompareRevisionActionTimeUserComment
117480view10:59, 21 May 2021EweitzModified title
105996view11:52, 16 August 2019MaintBotHMDB identifier normalization
89451view13:00, 15 September 2016Mkutmonremove space in ontology term id
80740view15:24, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
5-hydroxy-tryptophanMetabolite4350-09-8 (CAS)
AANATGeneProductENSBTAG00000014682 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:15
ACHEGeneProductENSBTAG00000001139 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:43
ASMTGeneProductENSBTAG00000047124 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:438
AcetylcholineMetabolite51-84-3 (CAS)
AcetylserotoninMetabolite1210-83-9 (CAS)
CHATGeneProductENSBTAG00000016814 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1103
COMTGeneProductENSBTAG00000019516 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1312
CholineMetabolite62-49-7 (CAS)
DBHGeneProductENSBTAG00000004508 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1621
DDCGeneProductENSBTAG00000020869 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1644
DopamineMetabolite62-31-7 (CAS)
EpinephrineMetaboliteHMDB0000068 (HMDB)
GABAMetaboliteHMDB0000112 (HMDB)
GAD1GeneProductENSBTAG00000007258 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2571
GAD2GeneProductENSBTAG00000008056 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2572
GlutamateMetabolite56-86-0 (CAS)
HDCGeneProductENSBTAG00000009911 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3067
HistamineMetabolite51-45-6 (CAS)
HistidineMetabolite71-00-1 (CAS)
L-DOPAMetabolite59-92-7 (CAS)
MAOAGeneProductENSBTAG00000016206 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4128
MelatoninMetaboliteHMDB0001389 (HMDB)
NorepinephrineMetabolite51-41-2 (CAS)
PAHGeneProductENSBTAG00000012794 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5053
PNMTGeneProductENSBTAG00000011731 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5409
PhenylalanineMetabolite63-91-2 (CAS)
SerotoninMetabolite50-67-9 (CAS)
THGeneProductENSBTAG00000026768 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7054
TPH1GeneProductENSBTAG00000005343 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7166
TryptophanMetabolite73-22-3 (CAS)
TyrosineMetabolite60-18-4 (CAS)

Annotated Interactions

No annotated interactions
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