Felbamate metabolism (Bos taurus)

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Annotate nodes Comment: 2 out of 13 DataNodes have a missing external reference. Check DataNode table at the bottom of the page. Please help improve this pathway by annotating gene, protein and metabolite nodes.

Approved version The current version of this pathway was approved for data analysis by Martina Kutmon.

Fix interactions Comment: 1 out of 10 lines are not properly connected. Please help improving this pathway by connecting the ends of interactions to nodes.

Homology Converted Comment: Inferred from another species Revision {{{tag_revision}}} of this pathway has been inferred from another species (tagged by Maintenance bot). Expression error: Unrecognised punctuation character "{"

Ontology Terms

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Bibliography

1. Glue P, Banfield CR, Perhach JL, Mather GG, Racha JK, Levy RH; ''Pharmacokinetic interactions with felbamate. In vitro-in vivo correlation.''; Clin Pharmacokinet, 1997 PubMed Europe PMC Scholia
2. Husain Z, Pinto C, Sofia RD, Yunis EJ; ''Felbamate-induced apoptosis of hematopoietic cells is mediated by redox-sensitive and redox-independent pathways.''; Epilepsy Res, 2002 PubMed Europe PMC Scholia

History

External references

DataNodes

Name	Type	Database reference	Comment
1.1.1.1	Protein
1.2.1.5	Protein
2-hydroxyfelbamate	Metabolite	8575477 (Chemspider)
3-Hydroxy-2-phenylpropyl carbamate	Metabolite	184751 (Chemspider)
3-carbamoyl-2-phenyl propionaldehyde	Metabolite	21350391 (PubChem-compound)
3-carbamoyl-2-phenyl propionic acid	Metabolite	3025746 (PubChem-compound)
CYP2E1	GeneProduct	ENSBTAG00000018365 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000130649
CYP3A4	GeneProduct	ENSBTAG00000047379 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000160868
Felbamate	Metabolite	HMDB0015084 (HMDB)
atropaldehyde	Metabolite	10312 (PubChem-compound)
p-hydroxyfelbamate	Metabolite	8096945 (Chemspider)

Annotated Interactions