Butyrate-induced histone acetylation (Bos taurus)

Description

Metabolism of butyrate is suggested to be an energy source for histone acetylation.

HomologyConvert: This pathway was inferred from Homo sapiens pathway WP2366(73980) with a 66.0% conversion rate.

View approved pathways at the new wikipathways.org.

Davie JR; ''Inhibition of histone deacetylase activity by butyrate.''; J Nutr, 2003 PubMed Europe PMC Scholia
Donohoe DR, Collins LB, Wali A, Bigler R, Sun W, Bultman SJ; ''The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation.''; Mol Cell, 2012 PubMed Europe PMC Scholia

Revision	Action	Time	User	Comment
115748	view	11:19, 9 March 2021	Egonw	Replaced the WP id of a human pathways with the matching cow pathway
102130	view	21:15, 1 December 2018	Egonw	Replaced Wikipedia with Wikidata identifiers.
89151	view	03:06, 23 August 2016	Ariutta	Ontology Term : 'classic metabolic pathway' added !
80881	view	15:29, 30 June 2015	Mkutmon	New pathway

View all...

Name	Type	Database reference	Comment
ACLY	Protein	ENSBTAG00000016740 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P53396
AKT1	Protein	ENSBTAG00000017636 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P31749
Acetyl CoA	Metabolite	CHEBI:15351 (ChEBI)
Acetylated Histone	Complex	Q36293 (Wikidata)
Butyrate	Metabolite	CHEBI:17968 (ChEBI)
Citrate	Metabolite	CHEBI:35808 (ChEBI)
Glucose	Metabolite	CHEBI:17634 (ChEBI)
HDACs	Protein
Lipid biosynthesis	Pathway	WP1020 (WikiPathways)
TCA cycle	Pathway	WP78 (WikiPathways)

No annotated interactions