NOTCH1 regulation of endothelial cell calcification (Homo sapiens)

Description

Model of NOTCH1 regulation of human endothelial cell calcification.

Proteins on this pathway have targeted assays available via the CPTAC Assay Portal

View approved pathways at the new wikipathways.org.

White MP, Theodoris CV, Liu L, Collins WJ, Blue KW, Lee JH, Meng X, Robbins RC, Ivey KN, Srivastava D; ''NOTCH1 regulates matrix gla protein and calcificationgene networks in human valve endothelium.''; J Mol Cell Cardiol, 2015 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
116601	view	09:29, 9 May 2021	Eweitz	Modified title
106657	view	21:17, 12 September 2019	Khanspers	Modified description
105658	view	05:15, 10 August 2019	Khanspers	Modified description
87953	view	13:07, 25 July 2016	Elisa	Ontology Term : 'regulatory pathway' added !
87385	view	11:05, 22 July 2016	MaintBot	added missing graphids
82217	view	20:45, 15 September 2015	Khanspers	updates
81814	view	06:06, 1 September 2015	Khanspers	Modified description
81813	view	06:04, 1 September 2015	Khanspers	New pathway

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Name	Type	Database reference
ALPL	GeneProduct	ENSG00000162551 (Ensembl)
CALU	GeneProduct	ENSG00000128595 (Ensembl)
DLL1	GeneProduct	ENSG00000198719 (Ensembl)
DLL3	GeneProduct	ENSG00000090932 (Ensembl)
DLL4	GeneProduct	ENSG00000128917 (Ensembl)
FGFR3	GeneProduct	ENSG00000068078 (Ensembl)
GJA5	GeneProduct	2702 (Entrez Gene)
ITGA1	GeneProduct	ENSG00000213949 (Ensembl)
JAG1	GeneProduct	ENSG00000101384 (Ensembl)
JAG2	GeneProduct	ENSG00000184916 (Ensembl)
MGP	Protein	ENSG00000111341 (Ensembl)
NOTCH1	GeneProduct	ENSG00000148400 (Ensembl)
PAR1	GeneProduct	ENSG00000198121 (Ensembl)
PLAT	Protein	ENSG00000104368 (Ensembl)
PTHrP	Protein	ENSG00000104368 (Ensembl)
SAT1	GeneProduct	ENSG00000130066 (Ensembl)
SOX6	GeneProduct	ENSG00000110693 (Ensembl)
VEGF	GeneProduct	ENSG00000112715 (Ensembl)

No annotated interactions