Central carbon metabolism (Escherichia coli)

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1ICTGlucosePYRAceCITSUCAce-CoAF6PFBPT3PGOXPEPG6PSUC-CoA2-OG6PGFUMMALOAAP5PGalactose


Description

No description

Comments

 
The pathway was drawn from Figure 1 in the paper.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Haverkorn van Rijsewijk BR, Nanchen A, Nallet S, Kleijn RJ, Sauer U; ''Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli.''; Mol Syst Biol, 2011 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
117433view10:50, 21 May 2021EweitzModified title
89169view03:42, 23 August 2016AriuttaOntology Term : 'classic metabolic pathway' added !
83523view08:34, 20 November 2015AnweshaNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
2-OGMetaboliteC00026 (KEGG Compound)
6PGMetaboliteC00345 (KEGG Compound)
Ace-CoAMetaboliteC00024 (KEGG Compound)
AceMetaboliteC00033 (KEGG Compound)
CITMetaboliteC00158 (KEGG Compound)
F6PMetaboliteC05345 (KEGG Compound)
FBPMetaboliteC05378 (KEGG Compound)
FUMMetaboliteC00122 (KEGG Compound)
G6P MetaboliteC00668 (KEGG Compound)
GOXMetabolite
GalactoseMetaboliteC00124 (KEGG Compound)
GlucoseMetaboliteC00221 (KEGG Compound)
ICTMetaboliteC00311 (KEGG Compound)
MALMetaboliteC00149 (KEGG Compound)
OAAMetaboliteC00036 (KEGG Compound)
P5PMetabolite
PEPMetaboliteC00074 (KEGG Compound)
PYRMetaboliteC00022 (KEGG Compound)
SUC-CoAMetaboliteC00091 (KEGG Compound)
SUCMetaboliteC00042 (KEGG Compound)
T3PMetaboliteC00197 (KEGG Compound)

Annotated Interactions

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SourceTargetTypeDatabase referenceComment
2-OGSUC-CoAArrowR01197 (KEGG Reaction)
6PGArrowWpR4 (WikiPathways)
6PGP5PArrowWpR11 (WikiPathways)
Ace-CoAAceArrowR00227 (KEGG Reaction)
Ace-CoAR00351 (KEGG Reaction)
Ace-CoAWpR12 (WikiPathways)
ArrowWpR13 (WikiPathways)
ArrowWpR4 (WikiPathways)
CITICTArrowWpR2 (WikiPathways)
  • R01325 : Citrate <=> cis-Aconitate + H2O
  • R01900 : Isocitrate <=> cis-Aconitate + H2O
F6PFBPArrowWpR6 (WikiPathways)
FBPT3PArrowWpR5 (WikiPathways)
FUMMALArrowR01082 (KEGG Reaction)
G6P 6PGArrowWpR3 (WikiPathways)
  • R02035 : D-Glucono-1,5-lactone 6-phosphate + H2O <=> 6-Phospho-D-gluconate
  • R02736 : beta-D-Glucose 6-phosphate + NADP+ <=> D-Glucono-1,5-lactone 6-phosphate + NADPH + H+
G6P F6PArrowR03321 (KEGG Reaction)
GOXMALArrowWpR12 (WikiPathways)
GalactoseG6P ArrowWpR7 (WikiPathways)
GlucoseG6P ArrowR01600 (KEGG Reaction)
ICT2-OGArrowR00709 (KEGG Reaction)
ICTGOXArrowWpR13 (WikiPathways)
MALOAAArrowR00361 (KEGG Reaction)
MALPYRArrowWpR9 (WikiPathways)
OAAArrowWpR10 (WikiPathways)
OAACITArrowR00352 (KEGG Reaction)
PEPArrowR00431 (KEGG Reaction)
PEPPYRArrowWpR8 (WikiPathways)
PYRAce-CoAArrowR00209 (KEGG Reaction)
SUC-CoASUCArrowR00432 (KEGG Reaction)
SUCFUMArrowR02164 (KEGG Reaction)
T3PPEPArrowWpR1 (WikiPathways)
  • R00658 : 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O
  • R01518 : 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate
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