Prostaglandin synthesis and regulation (Mus musculus)
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Gq signaling
pathway
prolactin
release
Cytoplasm
PG Synthases
Inactive Metabolites
Cell Membrane
Phospholipids
Cortisone
Ptgdr
Prl
Anxa4
Anxa6
Ptgds
Hsd11b2
Anxa2
Arachidonic acid
Ptger2
S100a10
Ednrb
Cortisol
Prostaglandin H2
Pla2g4a
Cortisol
Anxa1
Ptger1
Anxa8
Anxa3
Ptgir
Ptgfr
Calcium
Scgb1a1
Tbxas1
Ptgis
PGF2a
PGF2a
PGI2
S100a6
Hsd11b1
PGE2
Ptger4
TXA2
Edn1
Progesterone
Anxa5
Ptgs1
Ednra
Cyp11a1
Ptger3
Ptgs2
Hpgd
Calcium
Description
No description
Comments
GenMAPP notes
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks
See note for more details
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP98(r20887)
with a 83% conversion rate.
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Quality Tags
Ontology Terms
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Bibliography
Gross G, Imamura T, Muglia LJ; ''Gene knockout mice in the study of parturition.''; J Soc Gynecol Investig, 2000
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
117938
view
10:44, 23 May 2021
Eweitz
Modified title
114013
view
15:00, 17 December 2020
Fehrhart
added reference mentioned in description
114012
view
14:59, 17 December 2020
Fehrhart
connected line
109402
view
17:28, 16 March 2020
L Dupuis
Converted interactions to graphical lines
106885
view
13:36, 17 September 2019
MaintBot
HMDB identifier normalization
69204
view
18:24, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67608
view
11:32, 26 June 2013
Ddigles
Ontology Term : 'prostaglandin metabolic pathway' added !
41394
view
00:29, 2 March 2011
MaintBot
Removed redundant pathway information and comments
33046
view
21:44, 7 October 2009
MaintBot
Added xrefs
32411
view
17:05, 15 August 2009
MaintBot
Fixed text labels
32068
view
13:35, 14 August 2009
MaintBot
Fixed group labels
31443
view
21:07, 13 August 2009
MaintBot
Fixed text labels
30835
view
00:02, 30 July 2009
MaintBot
Converted from Homo sapiens
21465
view
11:31, 14 November 2008
MaintBot
[[Pathway:Mus musculus:Prostaglandin synthesis regulation]] moved to [[Pathway:WP374]]: Moved to stable identifier
8344
view
13:46, 7 January 2008
MaintBot
[[Pathway:Mouse:Prostaglandin synthesis regulation]] moved to [[Pathway:Mus musculus:Prostaglandin synthesis regulation]]: Renaming species
7790
view
16:17, 18 December 2007
MaintBot
fixed category names
7393
view
12:42, 4 November 2007
MaintBot
Added categories to GPML
6487
view
22:19, 22 May 2007
Nsalomonis
gpml file for [[Mouse:Prostaglandin_synthesis_regulation]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Anxa1
GeneProduct
16952 (Entrez Gene)
Anxa2
GeneProduct
12306 (Entrez Gene)
Anxa3
GeneProduct
11745 (Entrez Gene)
Anxa4
GeneProduct
11746 (Entrez Gene)
Anxa5
GeneProduct
11747 (Entrez Gene)
Anxa6
GeneProduct
11749 (Entrez Gene)
Anxa8
GeneProduct
11752 (Entrez Gene)
Arachidonic acid
Metabolite
HMDB0001043 (HMDB)
Calcium
Metabolite
HMDB0000464 (HMDB)
Cortisol
Metabolite
HMDB0000063 (HMDB)
Cyp11a1
GeneProduct
13070 (Entrez Gene)
Edn1
GeneProduct
13614 (Entrez Gene)
PMID: 1474344
Ednra
GeneProduct
13617 (Entrez Gene)
Ednrb
GeneProduct
13618 (Entrez Gene)
Hpgd
GeneProduct
15446 (Entrez Gene)
Hsd11b1
GeneProduct
15483 (Entrez Gene)
Hsd11b2
GeneProduct
15484 (Entrez Gene)
PGE2
Metabolite
HMDB0003175 (HMDB)
PGF2a
Metabolite
HMDB0001139 (HMDB)
PGI2
Metabolite
HMDB0001335 (HMDB)
Pla2g4a
GeneProduct
18783 (Entrez Gene)
Prl
GeneProduct
19109 (Entrez Gene)
Progesterone
Metabolite
HMDB0001830 (HMDB)
Prostaglandin H2
Metabolite
HMDB0001381 (HMDB)
Ptgdr
GeneProduct
19214 (Entrez Gene)
Ptgds
GeneProduct
19215 (Entrez Gene)
Ptger1
GeneProduct
19216 (Entrez Gene)
Ptger2
GeneProduct
19217 (Entrez Gene)
Ptger3
GeneProduct
19218 (Entrez Gene)
Ptger4
GeneProduct
19219 (Entrez Gene)
Ptgfr
GeneProduct
19220 (Entrez Gene)
Ptgir
GeneProduct
19222 (Entrez Gene)
Ptgis
GeneProduct
19223 (Entrez Gene)
Ptgs1
GeneProduct
19224 (Entrez Gene)
Ptgs2
GeneProduct
19225 (Entrez Gene)
S100a10
GeneProduct
20194 (Entrez Gene)
PMID: 12962548 relationship with Annexin 2
S100a6
GeneProduct
20200 (Entrez Gene)
Scgb1a1
GeneProduct
22287 (Entrez Gene)
PMID: 7615804, PMID: 3292559
TXA2
Metabolite
HMDB0001452 (HMDB)
Tbxas1
GeneProduct
21391 (Entrez Gene)
Annotated Interactions
No annotated interactions
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View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
Annotated Interactions
No annotated interactions