This MAPP was created using the GPCRDB (Horn et al., 1998), http://www.cmbi.kun.nl/7tm/. The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.
HomologyConvert
This pathway was inferred from Homo sapiens pathway WP501(r21732) with a 93% conversion rate.
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Annotated lists of gene products are considered useful for analysis and for stimulating future pathway curation.
Approved version
The current version of this pathway was approved for data analysis by Eric Weitz.
Add references
Please help improve this pathway by adding literature references. Remove this tag when completed.
Karchin R, Karplus K, Haussler D; ''Classifying G-protein coupled receptors with support vector machines''; Bioinformatics, 2002 PubMedEurope PMCScholia
Horn F, Weare J, Beukers MW, Hörsch S, Bairoch A, Chen W, Edvardsen O, Campagne F, Vriend G.; ''GPCRDB: an information system for G protein-coupled receptors''; Nucleic Acids Research, 1998 PubMedEurope PMCScholia
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