Insulin induced PI3K-Akt and MAPK in hepatocytes (Rattus norvegicus)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Glycolysis &Glycogen synthesisInsulin-1Grb10IRS2mLST8RaptormTORBADAclyERKSOS1Foxo1Gys1SHC-1RASEif4eAkt1s1IRS1S6KMEKGys2TSC1TSC2FoxK1LARP1Pi3KAktRhebGsk3RSK14eBPPfkfb2RAFNdrg1Rps6GRB2Fatty acid synthesisGrowth &DifferentiationCell size, growth &Protein synthesisName: Insulin induced PI3K-Akt and MAPK in hepatocytesOrganism: Rattus norvegicus


Description

Insulin-induced P13K-Akt and MAPK network in hepatocytes. Pathway is adapted from Figure 5 in the publication by Zhang et al (2017) in the Journal of Proteome Research

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Quality Tags

Image:Curated.pngApproved version

Ontology Terms

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Bibliography

  1. Zhang Y, Yu Y; ''Global Phosphoproteomic Analysis of Insulin/Akt/mTORC1/S6K Signaling in Rat Hepatocytes.''; J Proteome Res, 2017 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
96564
Approved
view10:16, 19 March 2018SusanOntology Term : 'hepatocyte' added !
96563view10:16, 19 March 2018SusanOntology Term : 'insulin signaling pathway' added !
96334view11:19, 8 March 2018SusanChanged arrow
96333view11:17, 8 March 2018SusanAdded Insulin
96332view11:08, 8 March 2018SusanNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
4eBPGeneProductENSRNOG00000012582 (Ensembl)
AclyGeneProductENSRNOG00000016924 (Ensembl)
Akt1s1GeneProductENSRNOG00000020289 (Ensembl)
AktGeneProductENSRNOG00000028629 (Ensembl)
BADGeneProductENSRNOG00000021147 (Ensembl)
ERKGeneProductENSRNOG00000001849 (Ensembl)
Eif4eGeneProductENSRNOG00000052343 (Ensembl)
FoxK1GeneProductENSRNOG00000001104 (Ensembl)
Foxo1GeneProductENSRNOG00000013397 (Ensembl)
GRB2GeneProductENSRNOG00000003990 (Ensembl)
Grb10GeneProductENSRNOG00000004290 (Ensembl)
Gsk3GeneProductENSRNOG00000020417 (Ensembl)
Gys1GeneProductENSRNOG00000020812 (Ensembl)
Gys2GeneProductENSRNOG00000059753 (Ensembl)
IRS1GeneProductENSRNOG00000014597 (Ensembl)
IRS2GeneProductENSRNOG00000023509 (Ensembl)
Insulin-1ProteinP01322 (Uniprot-TrEMBL)
LARP1GeneProductENSRNOG00000031544 (Ensembl)
MEKGeneProductENSRNOG00000053583 (Ensembl)
Ndrg1GeneProductENSRNOG00000007393 (Ensembl)
Pfkfb2GeneProductENSRNOG00000004162 (Ensembl)
Pi3KGeneProductENSRNOG00000017840 (Ensembl)
RAFGeneProductENSRNOG00000010153 (Ensembl)
RASGeneProductENSRNOG00000009338 (Ensembl)
RSK1GeneProductENSRNOG00000042411 (Ensembl)
RaptorGeneProductENSRNOG00000003821 (Ensembl)
RhebGeneProductENSRNOG00000050578 (Ensembl)
Rps6GeneProductENSRNOG00000007663 (Ensembl)
S6KGeneProductENSRNOG00000003919 (Ensembl)
SHC-1GeneProductENSRNOG00000020657 (Ensembl)
SOS1GeneProductENSRNOG00000007106 (Ensembl)
TSC1GeneProductENSRNOG00000011470 (Ensembl)
TSC2GeneProductENSRNOG00000011375 (Ensembl)
mLST8GeneProductENSRNOG00000009667 (Ensembl)
mTORGeneProductENSRNOG00000009615 (Ensembl)

Annotated Interactions

No annotated interactions

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