ncRNAs involved in STAT3 signaling in hepatocellular carcinoma (Homo sapiens)

Description

This pathway describes the influence of ncRNAs on the STAT3 pathway in hepatocellular carcinoma. The model is based on Fig 4 in Klingenberg et al.

View approved pathways at the new wikipathways.org.

Klingenberg M, Matsuda A, Diederichs S, Patel T; ''Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets.''; J Hepatol, 2017 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
108190	view	10:55, 29 November 2019	Fehrhart	Ontology Term : 'cancer pathway' added !
108189	view	10:55, 29 November 2019	Fehrhart	Ontology Term : 'hepatocyte' added !
105489	view	05:44, 8 August 2019	Khanspers	Modified description
105473	view	05:20, 8 August 2019	Khanspers	Modified description
98466	view	19:12, 7 September 2018	Khanspers	Ontology Term : 'altered Jak-Stat signaling pathway' added !
98465	view	19:12, 7 September 2018	Khanspers	Ontology Term : 'hepatocellular carcinoma' added !
98464	view	19:11, 7 September 2018	Khanspers	Modified description
98463	view	19:09, 7 September 2018	Khanspers	New pathway

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Name	Type	Database reference
DILC	Rna
IL11	GeneProduct	ENSG00000095752 (Ensembl)
IL11RA	GeneProduct	ENSG00000137070 (Ensembl)
IL6	GeneProduct	ENSG00000136244 (Ensembl)
IL6R	GeneProduct	ENSG00000160712 (Ensembl)
IL6ST	GeneProduct	ENSG00000134352 (Ensembl)
JAK1	GeneProduct	ENSG00000162434 (Ensembl)
JAK2	GeneProduct	ENSG00000096968 (Ensembl)
JAK3	GeneProduct	ENSG00000105639 (Ensembl)
MIR200A	GeneProduct	ENSG00000207607 (Ensembl)
MIR200B	GeneProduct	ENSG00000207730 (Ensembl)
MIR200C	GeneProduct	ENSG00000207713 (Ensembl)
MIR21	GeneProduct	ENSG00000284190 (Ensembl)
NFKB1	GeneProduct	ENSG00000109320 (Ensembl)
RELA	GeneProduct	ENSG00000173039 (Ensembl)
SOX4	GeneProduct	ENSG00000124766 (Ensembl)
STAT3	GeneProduct	ENSG00000168610 (Ensembl)
UCA1	GeneProduct	ENSG00000214049 (Ensembl)
ZEB1	GeneProduct	ENSG00000148516 (Ensembl)
lncRNA-ATB	Rna
lncSox4	Rna

No annotated interactions