Glycolysis and gluconeogenesis - for workshop (Homo sapiens)

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1GlycolysisGluconeogenesisENO3SLC2A2Glyceraldehyde 3PTriglyceride synthesisSLC2A1LDHCG6PCHK3MPC1ALDOCLDHAL6BLDHBALDOAHK1GlucosePFKLPCK1PyruvatePFKMGlucose-6PGAPDH2P-GlycerateDihydroxyacetone-PPGK23P-GlycerateFructose 6PPentose Phosphate PathwayAspartateGCKMPC21,3BP-GlyceratePKM2GlucoseENO2ALDOBPGK1SLC2A4MalateOxaloacetateFructose-1,6BPP-enolpyruvateSLC2A5PyruvateLDHATPI1PGAM1PKM2PFKPHK2PKLRSLC2A3MDH1LactateENO1Glycogen metabolismFBP1GOT1FBP2PGAM2Glucose-6P (open)PGIFructose 6P (open)GPI


Description

Do not delete.

This pathway is intended to use in a workshop setting, and represents a subset of the full "glycolysis and gluconeogenesis" pathway.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Bricker DK, Taylor EB, Schell JC, Orsak T, Boutron A, Chen YC, Cox JE, Cardon CM, Van Vranken JG, Dephoure N, Redin C, Boudina S, Gygi SP, Brivet M, Thummel CS, Rutter J; ''A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.''; Science, 2012 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
128073view00:42, 24 January 2024EweitzModified title
110562view16:58, 18 May 2020KhanspersModified description
109919view17:14, 6 April 2020KhanspersModified description
107170view14:25, 17 September 2019MaintBotChEBI identifier normalization
106800view13:28, 17 September 2019MaintBotHMDB identifier normalization
98730view23:31, 2 October 2018Khanspersupdated complexes
98728view23:14, 2 October 2018Khanspersfine tuning
98726view20:22, 2 October 2018KhanspersModified description
98725view20:22, 2 October 2018KhanspersModified description
98724view20:21, 2 October 2018KhanspersModified title
98723view20:21, 2 October 2018KhanspersNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
1,3BP-GlycerateMetaboliteHMDB0001270 (HMDB)
2P-GlycerateMetaboliteHMDB0000362 (HMDB)
3P-GlycerateMetaboliteHMDB0000807 (HMDB)
ALDOAGeneProduct226 (Entrez Gene)
ALDOBGeneProduct229 (Entrez Gene)
ALDOCGeneProduct230 (Entrez Gene)
AspartateMetaboliteHMDB0000191 (HMDB)
Dihydroxyacetone-PMetaboliteHMDB0001473 (HMDB)
ENO1GeneProduct2023 (Entrez Gene)
ENO2GeneProduct2026 (Entrez Gene)
ENO3GeneProduct2027 (Entrez Gene)
FBP1GeneProduct2203 (Entrez Gene)
FBP2GeneProduct8789 (Entrez Gene)
Fructose 6P (open)MetaboliteCHEBI:57579 (ChEBI) fructose-6-phosphate (2-) open form
Fructose 6PMetaboliteCHEBI:61527 (ChEBI)
Fructose-1,6BPMetaboliteHMDB0001058 (HMDB)
G6PCGeneProduct2538 (Entrez Gene) Not present in brain and muscle, so those organs can not produce their own glucose in the gluconeogenesis pathway
GAPDHGeneProductENSG00000111640 (Ensembl)
GCKGeneProduct2645 (Entrez Gene) Gck is mainly active in liver
GOT1GeneProduct2805 (Entrez Gene)
GPIGeneProduct2821 (Entrez Gene) glucose-6-phosphate isomerase
Glucose-6P (open)MetaboliteCHEBI:57584 (ChEBI) D-Glucose-6-Phosphate (2-) open form
Glucose-6PMetaboliteCHEBI:75052 (ChEBI) Glucose-6-Phosphate (2-)
GlucoseMetaboliteHMDB0000122 (HMDB)
Glyceraldehyde 3PMetaboliteHMDB0001112 (HMDB)
Glycogen metabolismPathwayWP500 (WikiPathways)
HK1GeneProduct3098 (Entrez Gene)
HK2GeneProduct3099 (Entrez Gene)
HK3GeneProduct3101 (Entrez Gene)
LDHAGeneProduct3939 (Entrez Gene)
LDHAL6BGeneProduct92483 (Entrez Gene)
LDHBGeneProduct3945 (Entrez Gene)
LDHCGeneProduct3948 (Entrez Gene)
LactateMetaboliteHMDB0000190 (HMDB)
MDH1GeneProduct4190 (Entrez Gene)
MPC1GeneProduct51660 (Entrez Gene)
MPC2GeneProduct25874 (Entrez Gene)
MalateMetaboliteHMDB0000744 (HMDB)
OxaloacetateMetaboliteHMDB0000223 (HMDB)
P-enolpyruvateMetaboliteHMDB0000263 (HMDB)
PCK1GeneProduct5105 (Entrez Gene)
PFKLGeneProduct5211 (Entrez Gene)
PFKMGeneProduct5213 (Entrez Gene)
PFKPGeneProduct5214 (Entrez Gene)
PGAM1GeneProduct5223 (Entrez Gene)
PGAM2GeneProduct5224 (Entrez Gene)
PGIGeneProduct5.3.1.9 (Enzyme Nomenclature) phosphoglucose isomerase (PGI)
PGK1GeneProduct5230 (Entrez Gene)
PGK2GeneProduct5232 (Entrez Gene)
PKLRGeneProduct5313 (Entrez Gene)
PKM2GeneProduct5315 (Entrez Gene)
Pentose Phosphate PathwayPathwayWP134 (WikiPathways)
PyruvateMetaboliteHMDB0000243 (HMDB)
SLC2A1GeneProduct6513 (Entrez Gene)
SLC2A2GeneProduct6514 (Entrez Gene)
SLC2A3GeneProduct6515 (Entrez Gene)
SLC2A4GeneProduct6517 (Entrez Gene)
SLC2A5GeneProduct6518 (Entrez Gene)
TPI1GeneProduct7167 (Entrez Gene)
Triglyceride synthesisPathwayWP325 (WikiPathways)

Annotated Interactions

No annotated interactions

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