MicroRNA network associated with chronic lymphocytic leukemia (Homo sapiens)
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Description
MicroRNA network associated with chronic lymphocytic leukemia (CLL). The pink interactions represent effects of deletions/mutations. The mir15/16-p53 feedback circuit was originally described in Fabbri et al.
Quality Tags
Ontology Terms
Saving...Bibliography
- Fabbri M, Bottoni A, Shimizu M, Spizzo R, Nicoloso MS, Rossi S, Barbarotto E, Cimmino A, Adair B, Wojcik SE, Valeri N, Calore F, Sampath D, Fanini F, Vannini I, Musuraca G, Dell'Aquila M, Alder H, Davuluri RV, Rassenti LZ, Negrini M, Nakamura T, Amadori D, Kay NE, Rai KR, Keating MJ, Kipps TJ, Calin GA, Croce CM; ''Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia.''; JAMA, 2011 PubMed Europe PMC Scholia
- Ciccone M, Calin GA; ''MicroRNAs in Chronic Lymphocytic Leukemia: An Old Disease with New Genetic Insights.''; Microrna, 2016 PubMed Europe PMC Scholia
- Auer RL, Riaz S, Cotter FE; ''The 13q and 11q B-cell chronic lymphocytic leukaemia-associated regions derive from a common ancestral region in the zebrafish.''; Br J Haematol, 2007 PubMed Europe PMC Scholia
History
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External references
DataNodes
| View all... |
| Name | Type | Database reference | Comment |
|---|---|---|---|
| BCL2 | GeneProduct | ENSG00000171791 (Ensembl)  | |
| MCL1 | GeneProduct | ENSG00000143384 (Ensembl) | |
| MIR15A | GeneProduct | ENSG00000283785 (Ensembl) | |
| MIR16-1 | GeneProduct | ENSG00000208006 (Ensembl) | |
| MIR34A | Rna | ENSG00000284357 (Ensembl) | |
| MIR34B | Rna | ENSG00000207811 (Ensembl) | |
| MIR34C | Rna | ENSG00000207562 (Ensembl) | |
| TP53 | GeneProduct | ENSG00000141510 (Ensembl) | |
| ZAP70 | GeneProduct | ENSG00000115085 (Ensembl) |
Annotated Interactions
No annotated interactions
