Glycosaminoglycan degradation (Homo sapiens)

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Description

Taken from KEGG: Glycosaminoglycan degradation - Homo sapiens (human) [1].

Some genes such as NAGZ could not be found, these have been left on the diagram as unannotated GeneProducts.

Linked with a dotted arrow to the GeneProduct nodes are diseases caused by mutation in the respective gene.

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Quality Tags

Ontology Terms

 

Bibliography

  1. ''Glycosaminoglycan degradation - Homo sapiens (human)''; KEGG,
  2. Ghiselli G, Maccarana M; ''Drugs affecting glycosaminoglycan metabolism.''; Drug Discov Today, 2016 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
136166view07:59, 21 December 2024EgonwAdded a literature reference, about drug targeting
136161view15:50, 20 December 2024EgonwCompleted the reference
136160view15:48, 20 December 2024EgonwURL of the KEGG pathway
110276view07:07, 2 May 2020EgonwReplaced secondary ChEBI identifiers with a primary identifiers.
109331view23:23, 13 March 2020KhanspersOntology Term : 'classic metabolic pathway' added !
109330view23:22, 13 March 2020KhanspersOntology Term : 'glycosaminoglycan degradation pathway' added !
109128view06:06, 18 February 2020RleeModified description
109127view06:04, 18 February 2020RleeModified description
109124view05:59, 18 February 2020RleeNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(Gal)1 (GlcNAc)1 (S)1MetaboliteG01391 (KEGG Glycan)
(Gal)1 (GlcNAc)2 (S)1MetaboliteG13074 (KEGG Glycan)
(Gal)1 (GlcNAc)2 (S)2MetaboliteG13073 (KEGG Glycan)
(Gal)2 (GlcNAc)2 (S)2MetaboliteG01977 (KEGG Glycan)
(Gal)2 (GlcNAc)2 (S)3MetaboliteG01945 (KEGG Glycan)
(GalNAc)1 (GlcA)1 (S)1MetaboliteG00872 (KEGG Glycan)
(GalNAc)2 (GlcA)1 (LIdoA)1 (S)2MetaboliteG13042 (KEGG Glycan)
(GalNAc)2 (GlcA)1 (LIdoA)1 (S)3MetaboliteG13041 (KEGG Glycan)
(GalNAc)2 (GlcA)1 (S)1MetaboliteG13043 (KEGG Glycan)
(GalNAc)2 (GlcA)1 (S)2MetaboliteG12336 (KEGG Glycan)
(GlcA)1 (GlcNAc)1 (S)1MetaboliteG09660 (KEGG Glycan)
(GlcA)1 (GlcNAc)1MetaboliteG02632 (KEGG Glycan)
(GlcA)1 (GlcNAc)1MetaboliteG10008 (KEGG Glycan)
(GlcA)1 (GlcNAc)2MetaboliteG00711 (KEGG Glycan)
(GlcA)2 (GlcN)1 (GlcNAc)1 (LIdoA)1 (S)3MetaboliteG13035 (KEGG Glycan)
(GlcA)2 (GlcN)1 (GlcNAc)1 (LIdoA)1 (S)4MetaboliteG13034 (KEGG Glycan)
(GlcA)2 (GlcN)1 (GlcNAc)1 (S)2MetaboliteG13037 (KEGG Glycan)
(GlcA)2 (GlcN)1 (GlcNAc)1 (S)3MetaboliteG13036 (KEGG Glycan)
(GlcA)2 (GlcNAc)1 (S)1MetaboliteG13040 (KEGG Glycan)
(GlcA)2 (GlcNAc)1 (S)2MetaboliteG13039 (KEGG Glycan)
(GlcA)2 (GlcNAc)2 (S)2MetaboliteG13038 (KEGG Glycan)
(GlcA)2 (GlcNAc)2MetaboliteG00526 (KEGG Glycan)
ARSBGeneProductENSG00000113273 (Ensembl)
Chondroitin sulfateMetaboliteCHEBI:37397 (ChEBI)
Dermatan sulfateMetaboliteCHEBI:18376 (ChEBI)
GALNSGeneProductENSG00000141012 (Ensembl)
GLB1GeneProductENSG00000170266 (Ensembl)
GNSGeneProductENSG00000135677 (Ensembl)
GUSBGeneProductENSG00000169919 (Ensembl)
GeneProductGeneProduct
HEXAGeneProductENSG00000213614 (Ensembl)
HEXBGeneProductENSG00000049860 (Ensembl)
HGSNATGeneProductENSG00000165102 (Ensembl)
HPSE2GeneProductENSG00000172987 (Ensembl)
HPSEGeneProductENSG00000173083 (Ensembl)
HYAL1GeneProductENSG00000114378 (Ensembl)
HYAL2GeneProductENSG00000068001 (Ensembl)
HYAL4GeneProductENSG00000106302 (Ensembl)
Heparan sulfateMetaboliteCHEBI:28815 (ChEBI)
IDSGeneProductENSG00000010404 (Ensembl)
IDUAGeneProductENSG00000127415 (Ensembl)
Keratan sulfateMetaboliteCHEBI:18331 (ChEBI)
NAGLUGeneProductENSG00000108784 (Ensembl)
SGSHGeneProductENSG00000181523 (Ensembl)
hyaluronanMetaboliteCHEBI:132153 (ChEBI)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP4815"
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