Lipid metabolism in senescent cells (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Subset PLA2 isozymesPlasma membraneSASPSenescence-associated secretory phenotypeHRASPLA2Cell cyclearrestLipid dropletsPTGS2PUFACDKN1ASLCO2A1ALOX5OxylipinTP53PLA2G3PLA2G2DPLA2G4APLA2G4CPLA2G4DPLA2G4EPLA2G4FPLA2G5PLA2G6PLA2G7PLA2G10PLA2G12APLA2G12BPLA2G1BFree PUFACytosolPTGS2OxylipinbiosynthesisName: Lipid metabolism in senescent cellsOrganism: Homo sapiens


Description

Description of the affected lipid metabolism in senecent cells.

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Quality Tags

Image:Curated.pngApproved version
Image:MissingXref.pngAnnotate nodes

Ontology Terms

Bibliography

  1. Wiley CD, Campisi J; ''The metabolic roots of senescence: mechanisms and opportunities for intervention.''; Nat Metab, 2021 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
134714
Approved
view12:29, 26 July 2024EweitzStandardize case, use singular
120374view20:35, 29 November 2021MkutmonOntology Term : 'cellular senescence pathway' added !
120372view20:34, 29 November 2021MkutmonOntology Term : 'lipid metabolic pathway' added !
120371view20:29, 29 November 2021Mkutmonadded subset PLA2 isozymes
120369view20:20, 29 November 2021MkutmonNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
ALOX5GeneProductENSG00000012779 (Ensembl)
CDKN1AGeneProductENSG00000124762 (Ensembl)
Cell cycle arrestPathway
Free PUFAMetaboliteCHEBI:26208 (ChEBI)
HRASGeneProductENSG00000174775 (Ensembl)
Lipid dropletsQ573950 (Wikidata)
Oxylipin biosynthesisPathway
OxylipinMetaboliteCHEBI:61121 (ChEBI)
PLA23.1.1.4 (Enzyme Nomenclature)
PLA2G10GeneProductENSG00000069764 (Ensembl)
PLA2G12AGeneProductENSG00000123739 (Ensembl)
PLA2G12BGeneProductENSG00000138308 (Ensembl)
PLA2G1BGeneProductENSG00000170890 (Ensembl)
PLA2G2DGeneProductENSG00000117215 (Ensembl)
PLA2G3GeneProductENSG00000100078 (Ensembl)
PLA2G4AGeneProductENSG00000116711 (Ensembl)
PLA2G4CGeneProductENSG00000105499 (Ensembl)
PLA2G4DGeneProductENSG00000159337 (Ensembl)
PLA2G4EGeneProductENSG00000188089 (Ensembl)
PLA2G4FGeneProductENSG00000168907 (Ensembl)
PLA2G5GeneProductENSG00000127472 (Ensembl)
PLA2G6GeneProductENSG00000184381 (Ensembl)
PLA2G7GeneProductENSG00000146070 (Ensembl)
PTGS2GeneProductENSG00000073756 (Ensembl)
PUFAMetaboliteCHEBI:26208 (ChEBI)
SLCO2A1GeneProductENSG00000174640 (Ensembl)
TP53GeneProductENSG00000141510 (Ensembl)

Annotated Interactions

No annotated interactions

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