Lac-Phe pathway (Mus musculus)

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1, 22Lac-PheABCC5Lac-Phe(S)-lactateL-phenylalanineCNDP2


Description

Lac-Phe is formed by Cndp2 and exported outside the cell, into the blood circulation by Abcc5. It is linked to food intake and obesity, where it is increased after exercise and suppresses food intake. Homology converted from WP5239

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Ontology Terms

 

Bibliography

  1. ''''; , PubMed Europe PMC Scholia
  2. ''''; , PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
124561view00:49, 9 November 2022EweitzModified description
123035view07:11, 20 June 2022EgonwRemoved the RHEA prefix
123030view08:39, 18 June 2022EgonwOntology Term : 'obesity' added !
123029view08:39, 18 June 2022EgonwOntology Term : 'signaling pathway' added !
123028view08:39, 18 June 2022EgonwOntology Term : 'classic metabolic pathway' added !
123025view08:38, 18 June 2022EgonwModified description
123022view08:36, 18 June 2022EgonwModified description
123020view08:30, 18 June 2022EgonwNew pathway

External references

DataNodes

NameTypeDatabase referenceComment
(S)-lactateMetabolite16651 (ChEBI)
ABCC5GeneProductQ9R1X5 (Uniprot-TrEMBL)
CNDP2ProteinQ9D1A2 (Uniprot-TrEMBL)
L-phenylalanineMetabolite58095 (ChEBI)
Lac-PheMetabolite167456 (ChEBI)

Annotated Interactions

SourceTargetTypeDatabase referenceComment
(S)-lactateLac-Phemim-conversion66724 (Rhea)
Lac-PheLac-Phe66720 (Rhea)
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5240"
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