17q12 copy number variation syndrome (Homo sapiens)

From WikiPathways

Jump to: navigation, search
chr17: 33,500,001Centromerechr17: 39,800,000Deleted Genes on 17q12 Microdeletion SyndromePlexin domain-containing protein 1 Ras-like proteinfamily member 10BProtein HEATR9PIP4K2BClass I peroxisomal membrane protein importTAF15CCL14Cyclin-dependent kinase 12 C-C motif chemokine 860S ribosomal protein L23DHRS11Peroxisomallipid metabolismC17orf78 39S ribosomal protein L45, mitochondrialIKZF3FamilialHyperlipidemiatype 1TBC1D3LRho GTPase-activating protein 23MED1RDM1MIEN1Receptortyrosine-protein kinase erbB-2Mitochondrial protein importPLXDC1TADA2ATMEM132E-DTTBC1D3KCWC25LIM and SH3 domain protein 1 RFFLSLFN13TBC1D3GPeroxisomal protein import CCL7Zinc finger protein Aiolos GPR179TBC1D3HC-C motif chemokine 15ACACAGAS2-like protein 2Schlafen family member 11Acid-sensing ion channel 2FBXL20CCL5E3 ubiquitin-protein ligase rififylinMRM1GAS2L2Matrix metalloproteinase-28TBC1D3ITECCCL16Synergin gammaTransmembrane protein 132ESLFN5Hepatocyte growth factor receptor signalingPCGF2Post-GPI attachment to proteins factor 3 Dehydrogenase/reductase SDR family member 11Zinc finger protein 830 HEATR9Notchless protein homolog 1 MYO19Zinc finger HIT domain-containing protein 3AP2B1NLE1Uncharacterized protein C17orf50STAC2STARD3TBC1 domain family member 3CMitochondrial iron-sulfur cluster biogenesis Familial Hyperlipidemia type 3 Elongin BC and Polycomb repressive complex 2-associated proteinEGFR tyrosine kinase inhibitor resistanceC-C motif chemokine 7TBC1D3SRCIN1CACNB1 SLFN14GRB7AATFInteractome of polycomb repressive complex 2 (PRC2)G-protein betagamma signalingSH3 and cysteine-rich domain-containing protein 2 F-box only protein 47DNA repair protein RAD51 homolog 4ZNF830DUSP14C-C motif chemokine 2C-C motif chemokine 5 SYNRGDNA ligase 3 Brain-derived neurotrophic factor (BDNF) signaling pathwayC-C motif chemokine 4-like PNMTDNA ReplicationMMP28TMEM132ERAD52 motif-containing protein 1C17orf50CCL8CDK12SLC35G3CCL3L1Presynaptic depolarizationand calciumchannel openingC-C motif chemokine 1Phosphatidylinositol-glycan biosynthesis class W proteinGrowth factor receptor-bound protein 7 Protein AF-17PGAP3HNF1BTBC1 domain family member 3G TATA-binding protein-associated factor 2NSuppressor of cytokine signaling 7 EotaxinProtein FoldingPEX12Putative ADP-ribosylation factor-like protein 5CCCL18RNA Polymerase II TranscriptionDNA Repair PathwaysARL5CASIC2 FBXO47ERBB2GeneC-C motif chemokine 18Mediator of RNA polymerase II transcription subunit 1 Nuclear receptorsNeurogenic differentiation factor 2Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signalingARHGAP23Tyrosine-protein kinase Tec Lysozyme-like protein 6 PIGWFibronectin type III domain-containing protein 8Probable G-protein coupled receptor 179RAD51D ProteinDual specificity protein phosphatase 14Voltage-dependent L-type calcium channel subunit beta-1C-C motif chemokine 3Migration and invasion enhancer 1RASL10BProtein phosphatase 1 regulatory subunit 1BTranscriptional adapter 2-alphaGGNBP2FNDC8MRPL45RPL23Peroxisome assembly protein 12Gamma-glutamyl cycle for the biosynthesis and degradation of glutathione, including diseasesp53 transcriptional gene networkC17orf98CCL11 LYZL6Brain-derived neurotrophic factor (BDNF) signaling pathwayGametogenetin-binding protein 2TBC1 domain family member 3LT-complex protein 1 subunit zeta-2 PPP1R1BTBC1D3BHepatitis B infectionC-C motif chemokine 3-like 1Prolactin receptor signalingC-C motif chemokine 14CISD3EPOPAcetyl-CoA carboxylase 1 StAR-related lipid transfer protein 3 SLFN12Schlafen familymember 13F-box/LRR-repeat protein 20TBC1 domain family member 3HC-C motif chemokine 13TBC1 domain family member 3KTBC1 domain family member 3IPhenylethanolamine N-methyltransferase TMEM132E-DTPolycomb group RING finger protein 2PathwayG protein signaling pathwaysProbable ATP-dependentRNA helicase DDX52Uncharacterized protein C17orf78 TBC1 domain family member 3BSolute carrier family 35 member G3CCL15rRNA modification in the mitochondrionCCL13rRNA methyltransferase1, mitochondrial Unconventional myosin-XIXSOCS7LIM/homeobox protein Lhx1 Protein unc-45 homolog BRibonuclease SLFN12CDGSH iron-sulfur domain-containing protein 3, mitochondrial Pre-mRNA-splicing factor CWC25 homolog CCT6BC-C motif chemokine 4CCL1LASP1Phosphatidylinositol 5-phosphate 4-kinase type-2 betaMLLT6Costimulation by the CD28 familyCCL4L2Protein SLFN14Schlafen family member 5C-C motif chemokine 16 CCL3AP-2 complex subunit betaSLFN11LIG3NRF2 pathway Degradation of beta-catenin by the destruction complex Telethonin NEUROD2TCAPCCL4UNC45BHepatocyte nuclearfactor 1-betaLHX1RAF/MAP kinase cascadeSRC kinase signaling inhibitor 1TBC1D3CIon ChannelTransport DDX52Uncharacterized protein C17orf98ZNHIT3Protein AATF HostInteractions of HIV factorsTBC1 domain family member 3Methionine metabolism leading to sulfur aminoacids and related disorders88174712251721459560105734612045714112954, 1191737102197661794, 11059, 1781381262614831101302779, 9156, 63, 127, 169177107301545080148120, 12313187715413758, 10665, 71143171166264, 16417TLK2P1 7390362618715, 521411682614839, 111, 11514836371481487512515637227211573576, 11286, 103172133513269, 71714812741037881716314810075314717015030, 10993, 99281111410118713011829, 32, 4915288, 121, 171448175258170148148745, 6112420, 458929315191086416126826, 8322, 674771531123, 55, 14013910479148166, 17443, 13842, 1468, 38577421621477851516913815813677126, 1352116010117692754019, 14216714868, 1491677944165172385777, 113334614865, 71, 15594849612813241173525134, 1447CCL298Chemokine Signaling Pathway159Chemokine Signaling Pathway159Chemokine Signaling Pathway159Chemokine Signaling Pathway159Chemokine Signaling PathwayChemokine Signaling Pathway159159E3 ubiquitin ligases ubiquitinate target proteinsProtein Folding34175Costimulation by the CD28 family104Protein Folding175Costimulation by the CD28 family104Protein Folding175Protein Folding175FamilialHyperlipidemiatype 1Protein Folding161175Costimulation by the CD28 family104Costimulation by the CD28 family104Protein Folding175Protein Folding175Costimulation by the CD28 family104Protein Folding175G protein signaling pathways168Protein Folding175FamilialHyperlipidemiatype 1161G protein signaling pathways168Costimulation by the CD28 family104Protein Folding175Protein Folding175Protein Folding175Brain-derived neurotrophic factor (BDNF) signaling pathwayProtein Folding175Protein Folding175FamilialHyperlipidemiatype 1Protein Folding161175FamilialHyperlipidemiatype 1161Protein Folding175Protein Folding175RNA Polymerase II Transcription85RAF/MAP kinase cascade92Protein Folding175Brain-derived neurotrophic factor (BDNF) signaling pathwayRAF/MAP kinase cascade92FamilialHyperlipidemiatype 1161Protein Folding175


Description

Overview of the 17q12 copy number variation syndrome, showing the involved genes, their pathways, and downstream events.

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

View all...
  1. F. Marti, A. Krause, N. H. Post, C. Lyddane, B. Dupont, M. Sadelain, P. D. King; ''Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6.''; , 2001 PubMed Europe PMC Scholia
  2. F. Pitel, V. Fillon, C. Heimel, N. Le Fur, C. el Khadir-Mounier, M. Douaire, J. Gellin, A. Vignal; ''Mapping of FASN and ACACA on two chicken microchromosomes disrupts the human 17q syntenic group well conserved in mammals.''; , 1998 PubMed Europe PMC Scholia
  3. Samia Hamimes, Hiroshi Arakawa, Alicja Z. Stasiak, Andrzej M. Kierzek, Seiki Hirano, Yun-Gui Yang, Minoru Takata, Andrzej Stasiak, Jean-Marie Buerstedde, Eric Van Dyck; ''RDM1, a novel RNA recognition motif (RRM)-containing protein involved in the cell response to cisplatin in vertebrates.''; , 2005 PubMed Europe PMC Scholia
  4. Drane P., Barel M., Balbo M., Frade R.; ''Identification of RB18A, a 205 kDa new p53 regulatory protein which shares antigenic and functional properties with p53.''; UniProt, 1997 PubMed Europe PMC Scholia
  5. Ponnambalam S., Robinson M.S.K, Jackson A.P., Peiperl L., Parham P.; ''Conservation and diversity in families of coated vesicle adaptins.''; UniProt, 1990 PubMed Europe PMC Scholia
  6. R. G. Gregg, P. A. Powers, K. Hogan; ''Assignment of the human gene for the beta subunit of the voltage-dependent calcium channel (CACNLB1) to chromosome 17 using somatic cell hybrids and linkage mapping.''; , 1993 PubMed Europe PMC Scholia
  7. Toshio Ota, Yutaka Suzuki, Tetsuo Nishikawa, Tetsuji Otsuki, Tomoyasu Sugiyama, Ryotaro Irie, Ai Wakamatsu, Koji Hayashi, Hiroyuki Sato, Keiichi Nagai, Kouichi Kimura, Hiroshi Makita, Mitsuo Sekine, Masaya Obayashi, Tatsunari Nishi, Toshikazu Shibahara, Toshihiro Tanaka, Shizuko Ishii, Jun-ichi Yamamoto, Kaoru Saito, Yuri Kawai, Yuko Isono, Yoshitaka Nakamura, Kenji Nagahari, Katsuhiko Murakami, Tomohiro Yasuda, Takao Iwayanagi, Masako Wagatsuma, Akiko Shiratori, Hiroaki Sudo, Takehiko Hosoiri, Yoshiko Kaku, Hiroyo Kodaira, Hiroshi Kondo, Masanori Sugawara, Makiko Takahashi, Katsuhiro Kanda, Takahide Yokoi, Takako Furuya, Emiko Kikkawa, Yuhi Omura, Kumi Abe, Kumiko Kamihara, Naoko Katsuta, Kazuomi Sato, Machiko Tanikawa, Makoto Yamazaki, Ken Ninomiya, Tadashi Ishibashi, Hiromichi Yamashita, Katsuji Murakawa, Kiyoshi Fujimori, Hiroyuki Tanai, Manabu Kimata, Motoji Watanabe, Susumu Hiraoka, Yoshiyuki Chiba, Shinichi Ishida, Yukio Ono, Sumiyo Taiguchi, Susumu Watanabe, Makoto Yosida, Tomoko Hotuta, Junko Kusano, Keiichi Kanehori, Asako Takahashi-Fujii, Hiroto Hara, Tomo-o Tanase, Yoshiko Nomura, Sakae Togiya, Fukuyo Komai, Reiko Hara, Kazuha Takeuchi, Miho Arita, Nobuyuki Imose, Kaoru Musashino, Hisatsugu Yuuki, Atsushi Oshima, Naokazu Sasaki, Satoshi Aotsuka, Yoko Yoshikawa, Hiroshi Matsunawa, Tatsuo Ichihara, Namiko Shiohata, Sanae Sano, Shogo Moriya, Hiroko Momiyama, Noriko Satoh, Sachiko Takami, Yuko Terashima, Osamu Suzuki, Satoshi Nakagawa, Akihiro Senoh, Hiroshi Mizoguchi, Yoshihiro Goto, Fumio Shimizu, Hirokazu Wakebe, Haretsug Hishigaki, Takeshi Watanabe, Akio Sugiyama, Makoto Takemoto, Bunsei Kawakami, Masaaki Yamazaki, Koji Watanabe, Ayako Kumagai,, Shoko Itakura, Yasuhito Fukuzumi, Yoshifumi Fujimori, Megumi Komiyama, Hiroyuki Tashiro, Akira Tanigami, Tsutomu Fujiwara, Toshihide Ono, Katsue Yamada, Yuka Fujii, Kouichi Ozaki, Maasa Hirao, Yoshihiro Ohmori, Ayako Kawabata, Takeshi Hikiji, Naoko Kobatake, Hiromi Inagaki, Yasuko Ikema, Sachiko Okamoto, Rie Okitani, Takuma Kawakami, Saori Noguchi, Tomoko Itoh, Keiko Shigeta, Tadashi Senba, Kyoka Matsumura, Yoshie Nakajima, Takae Mizuno, Misato Morinaga, Masahide Sasaki, Takushi Togashi, Masaaki Oyama, Hiroko Hata, Manabu Watanabe, Takami Komatsu, Junko Mizushima-Sugano, Tadashi Satoh, Yuko Shirai, Yukiko Takahashi, Kiyomi Nakagawa, Koji Okumura, Takahiro Nagase, Nobuo Nomura, Hisashi Kikuchi, Yasuhiko Masuho, Riu Yamashita, Kenta Nakai, Tetsushi Yada, Yusuke Nakamura, Osamu Ohara, Takao Isogai, Sumio Sugano; ''Complete sequencing and characterization of 21,243 full-length human cDNAs.''; , 2004 PubMed Europe PMC Scholia
  8. Benjamin T. Kile, Brenda A. Schulman, Warren S. Alexander, Nicos A. Nicola, Helene M. E. Martin, Douglas J. Hilton; ''The SOCS box: a tale of destruction and degradation ''; , 2002 PubMed Europe PMC Scholia
  9. W. F. Dong, H. H. Heng, R. Lowsky, Y. Xu, J. F. DeCoteau, X. M. Shi, L. C. Tsui, M. D. Minden; ''Cloning, expression, and chromosomal localization to 11p12-13 of a human LIM/HOMEOBOX gene, hLim-1.''; , 1997 PubMed Europe PMC Scholia
  10. D. L. Pittman, L. R. Weinberg, J. C. Schimenti; ''Identification, characterization, and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene.''; , 1998 PubMed Europe PMC Scholia
  11. E. Van Coillie, P. Fiten, H. Nomiyama, Y. Sakaki, R. Miura, O. Yoshie, J. Van Damme, G. Opdenakker; ''The human MCP-2 gene (SCYA8): cloning, sequence analysis, tissue expression, and assignment to the CC chemokine gene contig on chromosome 17q11.2.''; , 1997
  12. Hedrick J.A., Helms A., Vicari A., Zlotnik A.; ''Characterization of a novel CC chemokine, HCC-4, whose expression is increased by interleukin-10.''; UniProt9596672, 1998 PubMed Europe PMC Scholia
  13. Sarah J. Freemantle, Holly B. Portland, Katherine Ewings, Florence Dmitrovsky, Keith DiPetrillo, Michael J. Spinella, Ethan Dmitrovsky; ''Characterization and tissue-specific expression of human GSK-3-binding proteins FRAT1 and FRAT2''; WikiPathway, 2002 PubMed Europe PMC Scholia
  14. Cartwright R., Dunn A.M., Simpson P.J., Tambini C.E., Thacker J.; ''Isolation of novel human and mouse genes of the recA/RAD51 recombination- repair gene family.''; UniProt, 1998 PubMed Europe PMC Scholia
  15. F. Morohoshi, K. Arai, E. I. Takahashi, A. Tanigami, M. Ohki; ''Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins.''; , 1996 PubMed Europe PMC Scholia
  16. Furutani Y., Nomura H., Notake M., Oyamada Y., Fukui T., Yamada M., Larsen C.G., Oppenheim J.J., Matsushima K.; ''Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF)''; UniProt, 1989 PubMed Europe PMC Scholia
  17. Y. Hérault, D. Michel, G. Chatelain, G. Brun; ''cDNA and predicted amino acid sequences of the human ribosomal protein genes rpS12 and rpL17.''; , 1991 PubMed Europe PMC Scholia
  18. Dmitri Goriounov, Conrad L. Leung, Ronald K. H. Liem; ''Protein products of human Gas2-related genes on chromosomes 17 and 22 (hGAR17 and hGAR22) associate with both microfilaments and microtubules.''; , 2003 PubMed Europe PMC Scholia
  19. G. N. Marchenko, A. Y. Strongin; ''MMP-28, a new human matrix metalloproteinase with an unusual cysteine-switch sequence is widely expressed in tumors.''; , 2001 PubMed Europe PMC Scholia
  20. Sarah J. Fletcher, Vera P. Pisareva, Abdullah O. Khan, Andrew Tcherepanov, Neil V. Morgan, Andrey V. Pisarev; ''Role of the novel endoribonuclease SLFN14 and its disease-causing mutations in ribosomal degradation''; , 2018 PubMed Europe PMC Scholia
  21. H. Nomiyama, S. Fukuda, M. Iio, S. Tanase, R. Miura, O. Yoshie; ''Organization of the chemokine gene cluster on human chromosome 17q11.2 containing the genes for CC chemokine MPIF-1, HCC-2, HCC-1, LEC, and RANTES.''; , 1999 PubMed Europe PMC Scholia
  22. E. C. Koc, W. Burkhart, K. Blackburn, M. B. Moyer, D. M. Schlatzer, A. Moseley, L. L. Spremulli; ''The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.''; , 2001 PubMed Europe PMC Scholia
  23. Morihisa Fujita, Mariko Umemura, Takehiko Yoko-o, Yoshifumi Jigami; ''PER1 is required for GPI-phospholipase A2 activity and involved in lipid remodeling of GPI-anchored proteins.''; , 2006 PubMed Europe PMC Scholia
  24. Sato K., Mano H., Ariyama T., Inazawa J., Yazaki Y., Hirai H.; ''Molecular cloning and analysis of the human Tec protein-tyrosine kinase.''; UniProt, 1994 PubMed Europe PMC Scholia
  25. Schall T.J., Jongstra J., Dyer B.J., Jorgensen J., Clayberger C., Davis M.M., Krensky A.M.; ''A human T cell-specific molecule is a member of a new gene family.''; Uniprot, 1988 PubMed Europe PMC Scholia
  26. K. Naruse, M. Ueno, T. Satoh, H. Nomiyama, H. Tei, M. Takeda, D. H. Ledbetter, E. V. Coillie, G. Opdenakker, N. Gunge, Y. Sakaki, M. Iio, R. Miura; ''A YAC contig of the human CC chemokine genes clustered on chromosome 17q11.2.''; , 1996 PubMed Europe PMC Scholia
  27. Shawna Leslie Organ, Ming-Sound Tsao; ''An overview of the c-MET signaling pathway''; WikiPathways, 2011 PubMed Europe PMC Scholia
  28. Yamamoto T., Ikawa S., Akiyama T., Semba K., Nomura N., Miyajima N., Saito T., Toyoshima K.; ''Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor.''; UniProt, 1986 PubMed Europe PMC Scholia
  29. T. K. Ko, E. Kelly, J. Pines; ''CrkRS: a novel conserved Cdc2-related protein kinase that colocalises with SC35 speckles.''; , 2001 PubMed Europe PMC Scholia
  30. C. Tomasetto, C. Régnier, C. Moog-Lutz, M. G. Mattei, M. P. Chenard, R. Lidereau, P. Basset, M. C. Rio; ''Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17.''; , 1995 PubMed Europe PMC Scholia
  31. Garcia-Zepeda E.A., Rothenberg M.E., Ownbey T.R., Leder P., Luster A.D.; ''Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia.''; UniProt, 1996
  32. Marcos Malumbres, Edward Harlow, Tim Hunt, Tony Hunter, Jill M. Lahti, Gerard Manning, David O. Morgan, Li-Huei Tsai, Debra J. Wolgemuth; ''Cyclin-dependent kinases: a family portrait''; , 2009 PubMed Europe PMC Scholia
  33. C. T. Kuan, C. J. Wikstrand, D. D. Bigner; ''EGF mutant receptor vIII as a molecular target in cancer therapy''; WikiPathway, 2001 PubMed Europe PMC Scholia
  34. Kanji Okumoto 1 , Hiromi Noda 2 , Yukio Fujiki 3; ''Distinct modes of ubiquitination of peroxisome-targeting signal type 1 (PTS1) receptor Pex5p regulate PTS1 protein import''; WikiPathway, 2014 PubMed Europe PMC Scholia
  35. Robert L. Strausberg, Elise A. Feingold, Lynette H. Grouse, Jeffery G. Derge, Richard D. Klausner, Francis S. Collins, Lukas Wagner, Carolyn M. Shenmen, Gregory D. Schuler, Stephen F. Altschul, Barry Zeeberg, Kenneth H. Buetow, Carl F. Schaefer, Narayan K. Bhat, Ralph F. Hopkins, Heather Jordan, Troy Moore, Steve I. Max, Jun Wang, Florence Hsieh, Luda Diatchenko, Kate Marusina, Andrew A. Farmer, Gerald M. Rubin, Ling Hong, Mark Stapleton, M. Bento Soares, Maria F. Bonaldo, Tom L. Casavant, Todd E Scheetz, Michael J. Brownstein, Ted B. Usdin, Shiraki Toshiyuki, Piero Carninci, Christa Prange, Sam S. Raha, Naomi A. Loquellano, Garrick J. Peters, Rick D. Abramson, Sara J. Mullahy, Stephanie A. Bosak, Paul J. McEwan, Kevin J. McKernan, Joel A. Malek, Preethi H. Gunaratne, Stephen Richards, Kim C. Worley, Sarah Hale, Angela M. Garcia, Laura J. Gay, Stephen W. Hulyk, Debbie K. Villalon, Donna M. Muzny, Erica J. Sodergren,, Xiuhua Lu, Richard A. Gibbs, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha Madan, Stephanie Rodrigues, Amy Sanchez, Michelle Whiting, Anup Madan, Alice C. Young, Yuriy Shevchenko, Gerard G. Bouffard, Robert W. Blakesley, Jeffrey W. Touchman, Eric D. Green, Mark C. Dickson, Alex C Rodriguez, Jane Grimwood, Jeremy Schmutz, Richard M. Myers, Yaron S. N. Butterfield, Martin I. Krzywinski, Ursula Skalska, Duane E. Smailus, Angelique Schnerch, Jacqueline E. Schein, Steven J. M. Jones, Marco A. Marra, Mammalian Gene Collection Program Team; ''Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.''; , 2002 PubMed Europe PMC Scholia
  36. C. C. Chang, W. H. Lee, H. Moser, D. Valle, S. J. Gould; ''Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogenesis disorders.''; , 1997
  37. L. J. Page, P. J. Sowerby, W. W. Lui, M. S. Robinson; ''Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin.''; , 1999 PubMed Europe PMC Scholia
  38. K. Matuoka, H. Miki, K. Takahashi, T. Takenawa; ''A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs.''; , 1997 PubMed Europe PMC Scholia
  39. Artyom A. Alekseyenko, Andrey A. Gorchakov, Peter V. Kharchenko, Mitzi I. Kuroda; ''Reciprocal interactions of human C10orf12 and C17orf96 with PRC2 revealed by BioTAP-XL cross-linking and affinity purification.''; , 2014 PubMed Europe PMC Scholia
  40. Price M.P., Snyder P.M., Welsh M.J.; ''Cloning and expression of a novel human brain Na+ channel.''; , 1996 PubMed Europe PMC Scholia
  41. Martina Biermanns, Jutta von Laar, Ute Brosius, Jutta Gärtner; ''The peroxisomal membrane targeting elements of human peroxin 2 (PEX2)''; WikiPathway, 2003 PubMed Europe PMC Scholia
  42. Hilary F. Clark, Austin L. Gurney, Evangeline Abaya, Kevin Baker, Daryl Baldwin, Jennifer Brush, Jian Chen, Bernard Chow, Clarissa Chui, Craig Crowley, Bridget Currell, Bethanne Deuel, Patrick Dowd, Dan Eaton, Jessica Foster, Christopher Grimaldi, Qimin Gu, Philip E. Hass, Sherry Heldens, Arthur Huang, Hok Seon Kim, Laura Klimowski, Yisheng Jin, Stephanie Johnson, James Lee, Lhney Lewis, Dongzhou Liao, Melanie Mark, Edward Robbie, Celina Sanchez, Jill Schoenfeld, Somasekar Seshagiri, Laura Simmons, Jennifer Singh, Victoria Smith, Jeremy Stinson, Alicia Vagts, Richard Vandlen, Colin Watanab, David Wieand, Kathryn Woods, Ming-Hong Xie, Daniel Yansura, Sothy Yi, Guoying Yu, Jean Yuan, Min Zhang, Zemin Zhang, Audrey Goddard, William I Wood, Paul Godowski, Alane Gray; ''The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.''; , 2003 PubMed Europe PMC Scholia
  43. M. Hirashima, T. Ono, M. Nakao, H. Nishi, A. Kimura, H. Nomiyama, F. Hamada, M. C. Yoshida, K. Shimada; ''Nucleotide sequence of the third cytokine LD78 gene and mapping of all three LD78 gene loci to human chromosome 17.''; , 1992 PubMed Europe PMC Scholia
  44. S. Diriong, P. Lory, M. E. William, S. B. Ellis, M. M. Harpold, S. Taviaux; ''Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits''; WikiPathways, 1995 PubMed Europe PMC Scholia
  45. D. A. Schwarz, C. D. Katayama, S. M. Hedrick; ''Schlafen, a new family of growth regulatory genes that affect thymocyte development''; , 1998 PubMed Europe PMC Scholia
  46. Y. F. Wei, P. Robins, K. Carter, K. Caldecott, D. J. Pappin, G. L. Yu, R. P. Wang, B. K. Shell, R. A. Nash, P. Schär, et al.; ''Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination.''; , 1995 PubMed Europe PMC Scholia
  47. Alyssa M. Kaiser, Laura D. Attardi; ''Deconstructing networks of p53-mediated tumor suppression in vivo''; WikiPathway, 2018 PubMed Europe PMC Scholia
  48. Scott T. R. Walsh, Anthony A. Kossiakoff; ''Crystal structure and site 1 binding energetics of human placental lactogen''; WikiPathways, 2006 PubMed Europe PMC Scholia
  49. T. Nagase, K. Ishikawa, M. Suyama, R. Kikuno, M. Hirosawa, N. Miyajima, A. Tanaka, H. Kotani, N. Nomura, O. Ohara; ''Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.''; , 1998 PubMed Europe PMC Scholia
  50. Cameron P Bracken 1 , Steven J Wall, Benjamin Barré, Kostya I Panov, Paul M Ajuh, Neil D Perkins; ''Regulation of cyclin D1 RNA stability by SNIP1''; WikiPathway, 2008 PubMed Europe PMC Scholia
  51. Greg Kabachinski, Thomas U. Schwartz; ''The nuclear pore complex--structure and function at a glance''; WikiPathway, 2015 PubMed Europe PMC Scholia
  52. F. Morohoshi, Y. Ootsuka, K. Arai, H. Ichikawa, S. Mitani, N. Munakata, M. Ohki; ''Genomic structure of the human RBP56/hTAFII68 and FUS/TLS genes.''; , 1998 PubMed Europe PMC Scholia
  53. Price M.G., Landsverk M.L., Barral J.M., Epstein H.F.; ''Two mammalian UNC-45 isoforms are related to distinct cytoskeletal and muscle-specific functions.''; UniProt, 2002 PubMed Europe PMC Scholia
  54. Y. Zhu, C. Qi, S. Jain, M. S. Rao, J. K. Reddy; ''Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor.''; , 1997 PubMed Europe PMC Scholia
  55. Yusuke Maeda, Yuko Tashima, Toshiaki Houjou, Morihisa Fujita, Takehiko Yoko-o, Yoshifumi Jigami, Ryo Taguchi, Taroh Kinoshita; ''Fatty acid remodeling of GPI-anchored proteins is required for their raft association.''; , 2007 PubMed Europe PMC Scholia
  56. Alexander Dikiy, Sergey V. Novoselov, Dmitri E. Fomenko, Aniruddha Sengupta, Bradley A. Carlson, Ronald L. Cerny, Krzysztof Ginalski, Nick V. Grishin, Dolph L. Hatfield, Vadim N. Gladyshev; ''SelT, SelW, SelH, and Rdx12: genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family.''; , 2007 PubMed Europe PMC Scholia
  57. R. Candau, P. A. Moore, L. Wang, N. Barlev, C. Y. Ying, C. A. Rosen, S. L. Berger; ''Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5.''; , 1996 PubMed Europe PMC Scholia
  58. B. St. Croix, C. Rago, V. Velculescu, G. Traverso, K. E. Romans, E. Montgomery, A. Lal, G. J. Riggins, C. Lengauer, B. Vogelstein, K. W. Kinzler; ''Genes expressed in human tumor endothelium.''; , 2000 PubMed Europe PMC Scholia
  59. Jiangxia Li, Xiaohan Zhao, Qian Xin, Shan Shan, Baichun Jiang, Yecheng Jin, Huijun Yuan, Pu Dai, Ruo Xiao, Qingyan Zhang, Jingjing Xiao, Changshun Shao, Yaoqin Gong, Qiji Liu; ''''; , PubMed Europe PMC Scholia
  60. Hideru Obinata, Andrew Kuo, Yukata Wada, Steven Swendeman, Catherine H Liu, Victoria A Blaho, Rieko Nagumo, Kenichi Satoh, Takashi Izumi, Timothy Hla; ''Identification of ApoA4 as a sphingosine 1-phosphate chaperone in ApoM- and albumin-deficient mice''; WikiPathway, 2019 PubMed Europe PMC Scholia
  61. Jin-Yu Yang, Xiang-Yu Deng, Yi-Sheng Li, Xian-Cai Ma, Jian-Xiong Feng, Bing Yu, Yang Chen, Yi-Ling Luo, Xi Wang, Mei-Ling Chen, Zhi-Xin Fang, Fu-Xiang Zheng, Yi-Ping Li, Qian Zhong, Tie-Bang Kang, Li-Bing Song, Rui-Hua Xu, Mu-Sheng Zeng, Wei Chen, Hui Zhang, Wei Xie, Song Gao; ''Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control''; , 2018 PubMed Europe PMC Scholia
  62. Abu-Elheiga L., Jayakumar A., Baldini A., Chirala S.S., Wakil S.J.; ''Human acetyl-CoA carboxylase: characterization, molecular cloning, and evidence for two isoforms.''; UniProt, 1995 PubMed Europe PMC Scholia
  63. Masuko Katoh, Masaru Katoh; ''MGC9753 gene, located within PPP1R1B-STARD3-ERBB2-GRB7 amplicon on human chromosome 17q12, encodes the seven-transmembrane receptor with extracellular six-cystein domain.''; , 2003 PubMed Europe PMC Scholia
  64. Y. Hosokawa, Y. Maeda, E. i. Takahashi, M. Suzuki, M. Seto; ''Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping''; , 1999 PubMed Europe PMC Scholia
  65. Lin Pei, Yue Peng, Ying Yang, Xuefeng Bruce Ling, Winfried G Van Eyndhoven, Ken C Q Nguyen, Mark Rubin, Timothy Hoey, Scott Powers, Jing Li; ''PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer. ''; , 2002 PubMed Europe PMC Scholia
  66. Kishi T., Sasaki H., Akiyama N.,, Ishizuka T., Sakamoto H., Aizawa S., Sugimura T., Terada M.; ''Molecular cloning of human GRB-7 co-amplified with CAB1 and c-ERBB-2 in primary gastric cancer.''; UniProt, 1997 PubMed Europe PMC Scholia
  67. Zhaolei Zhang, Mark Gerstein; ''Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome.''; , 2003 PubMed Europe PMC Scholia
  68. Florian Odronitz, Martin Kollmar; ''Drawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 species''; , 2007 PubMed Europe PMC Scholia
  69. Lin Pei, Yue Peng, Ying Yang, Xuefeng Bruce Ling, Winfried G. Van Eyndhoven, Ken C. Q. Nguyen, Mark Rubin, Timothy Hoey, Scott Powers, Jing Li; ''PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.''; , 2002 PubMed Europe PMC Scholia
  70. Huafei Zou, Lide Hu, Jixi Li, Shuxuan Zhan, Kaiming Cao; ''Cloning and characterization of a novel small monomeric GTPase, RasL10B, with tumor suppressor potential.''; , 2006 PubMed Europe PMC Scholia
  71. Didier Hodzic, Chen Kong, Marisa J. Wainszelbaum, Audra J. Charron, Xiong Su, Philip D. Stahl; ''TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.''; , 2006 PubMed Europe PMC Scholia
  72. The MGC Project Team; ''The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).''; UniProt, 2004 PubMed Europe PMC Scholia
  73. Stefano Schiaffino, Cristina Mammucari; ''Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models''; WikiPathways, 2011 PubMed Europe PMC Scholia
  74. Youn B.-S., Zhang S.M., Lee E.K., Park D.H., Broxmeyer H.E., Murphy P.M., Locati M., Pease J.E., Kim K.K.[...], Kwon B.S.; ''Molecular cloning of leukotactin-1: a novel human beta-chemokine, a chemoattractant for neutrophils, monocytes, and lymphocytes, and a potent agonist at CC chemokine receptors 1 and 3.''; UniProt, 1997 PubMed Europe PMC Scholia
  75. G. Opdenakker, G. Froyen, P. Fiten, P. Proost, J. Van Damme; ''Human monocyte chemotactic protein-3 (MCP-3): molecular cloning of the cDNA and comparison with other chemokines.''; , 1993 PubMed Europe PMC Scholia
  76. Jiaxing Chen, Leslie A. Kuhn; ''Deciphering the three-domain architecture in schlafens and the structures and roles of human schlafen12 and serpinB12 in transcriptional regulation.''; , 2019 PubMed Europe PMC Scholia
  77. T. Nagase, R. Kikuno, K. Ishikawa, M. Hirosawa, O. Ohara; ''Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.''; , 2000 PubMed Europe PMC Scholia
  78. Stéphane Schmucker, Alain Martelli, Florent Colin, Adeline Page, Mari, Wattenhofer-Donzé, Laurence Reutenauer, Hélène Puccio; ''Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex''; WikiPathways, 2011 PubMed Europe PMC Scholia
  79. K. Hieshima, T. Imai, M. Baba, K. Shoudai, K. Ishizuka, T. Nakagawa, J. Tsuruta, M. Takeya, Y. Sakaki, K. Takatsuki, R. Miura, G. Opdenakker, J. Van Damme, O. Yoshie, H. Nomiyama; ''A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes.''; , 1997 PubMed Europe PMC Scholia
  80. Carsten Brock, Michael Schaefer, H. Peter Reusch, Cornelia Czupalla, Manuela Michalke, Karsten Spicher, Günter Schultz, Bernd Nürnberg; ''Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma''; WikiPathways, 2003 PubMed Europe PMC Scholia
  81. Juan Xiao, Tao Zhang, Daichao Xu, Huibing Wang, Yu Cai, Taijie Jin, Min Liu, Mingzhi Jin, Kejia Wu, Junying Yuan; ''FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation.''; , 2015 PubMed Europe PMC Scholia
  82. Ken-Wing Lee, Cynthia Okot-Kotber, Joseph F. LaComb, Daniel F. Bogenhagen; ''Mitochondrial ribosomal RNA (rRNA) methyltransferase family members are positioned to modify nascent rRNA in foci near the mitochondrial DNA nucleoid.''; , 2013 PubMed Europe PMC Scholia
  83. D. E. Iles, B. Segers, R. C. Sengers, K. Monsieurs, L. Heytens, P. J. Halsall, P. M. Hopkins, F. R. Ellis, J. L. Hall-Curran, A. D. Stewart, et al.; ''Genetic mapping of the beta 1- and gamma-subunits of the human skeletal muscle L-type voltage-dependent calcium channel on chromosome 17q and exclusion as candidate genes for malignant hyperthermia susceptibility''; , 1993 PubMed Europe PMC Scholia
  84. Iwahashi H., Yamagata K., Yoshiuchi I., Terasaki J., Yang Q., Fukui K., Ihara A., Zhu Q., Asakura T.[...],, Matsuzawa Y.; ''Thyroid hormone receptor interacting protein 3 (trip3) is a novel coactivator of hepatocyte nuclear factor-4alpha.''; UniProt, 2002 PubMed Europe PMC Scholia
  85. E. Martinez, H. Ge, Y. Tao, C. X. Yuan, V. Palhan, R. G. Roeder; ''Novel cofactors and TFIIA mediate functional core promoter selectivity by the human TAFII150-containing TFIID complex''; WikiPathways, 1998 PubMed Europe PMC Scholia
  86. C. C. Gregorio, K. Trombitás, T. Centner, B. Kolmerer, G. Stier, K. Kunke, K. Suzuki, F. Obermayr, B. Herrmann, H. Granzier, H. Sorimachi, S. Labeit; ''The NH2 terminus of titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity''; , 1998 PubMed Europe PMC Scholia
  87. Franck Coumailleau, Vincent Das, Andres Alcover, Graça Raposo, Sandrine Vandormael-Pournin, Stéphanie Le Bras, Patricia Baldacci, Alice Dautry-Varsat, Charles Babinet, Michel Cohen-Tannoudji; ''Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment.''; , 2004 PubMed Europe PMC Scholia
  88. A. M. Castellino, G. J. Parker, I. V. Boronenkov, R. A. Anderson, M. V. Chao; ''A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase''; , 1997 PubMed Europe PMC Scholia
  89. A. Ishida, H. Asano, M. Hasegawa, H. Koseki, T. Ono, M. C. Yoshida, M Taniguchi, M Kanno; ''Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif.''; , 1993 PubMed Europe PMC Scholia
  90. Bailey S.D., Xie C., Do R., Montpetit A., Diaz R., Mohan V., Keavney B., Yusuf S., Gerstein H.C.[...], Anand S.; ''Variation at the NFATC2 locus increases the risk of thiazolidinedione- induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.''; UniProt, 2010 PubMed Europe PMC Scholia
  91. Y. Tasaki, S. Fukuda, M. Iio, R. Miura, T. Imai, S. Sugano, O. Yoshie, A. L. Hughes, H. Nomiyama; ''Chemokine PARC gene (SCYA18) generated by fusion of two MIP-1alpha/LD78alpha-like genes.''; , 1999 PubMed Europe PMC Scholia
  92. C. S. Mason, C. J. Springer, G. Cooper, G. Superti-Furga, C. J. Marshall, R. Marais; ''Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation''; WikiPathways, 1999 PubMed Europe PMC Scholia
  93. Sandra E. Wiley, Mark L. Paddock, Edward C. Abresch, Larry Gross, Peter van der Geer, Rachel Nechushtai, Anne N. Murphy, Patricia A. Jennings, Jack E. Dixon; ''The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster.''; , 2007 PubMed Europe PMC Scholia
  94. K. Ozaki, T. Kuroki, S. Hayashi, Y. Nakamura; ''Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA display method.''; , 1996 PubMed Europe PMC Scholia
  95. F. Stanchi, E. Bertocco, S. Toppo, R. Dioguardi, B. Simionati, N. Cannata, R. Zimbello, G. Lanfranchi, G. Valle; ''Characterization of 16 novel human genes showing high similarity to yeast sequences.''; , 2001 PubMed Europe PMC Scholia
  96. J. W. Lee, H. S. Choi, J. Gyuris, R. Brent, D. D. Moore; ''''; ,
  97. M. Therrien, H. C. Chang, N. M. Solomon, F. D. Karim, D. A. Wassarman, G. M. Rubin; ''KSR, a novel protein kinase required for RAS signal transduction''; , 1995 PubMed Europe PMC Scholia
  98. M. Mehrabian, R. S. Sparkes, T. Mohandas, A. M. Fogelman, A: J. Lusis; ''Localization of monocyte chemotactic protein-1 gene (SCYA2) to human chromosome 17q11.2-q21.1.''; ,
  99. Sandra E. Wiley, Anne N. Murphy, Stuart A. Ross, Peter van der Geer, Jack E. Dixon; ''MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity.''; , 2007 PubMed Europe PMC Scholia
  100. T. Nagase, R. Kikuno, A. Hattori, Y. Kondo, K. Okumura, O. Ohara; ''Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.''; , 2000 PubMed Europe PMC Scholia
  101. Barbara Simon-Kayser, Catherine Scoul, Karine Renaudin, Pascal Jezequel, Olivier Bouchot, Jérôme Rigaud, Stéphane Bezieau; ''Molecular cloning and characterization of FBXO47, a novel gene containing an F-box domain, located in the 17q12 band deleted in papillary renal cell carcinoma.''; , 2005 PubMed Europe PMC Scholia
  102. Lipes M.A., Napolitano M., Jeang K.-T., Chang N.T., Leonard W.J.; ''Identification, cloning, and characterization of an immune activation gene.''; UniProt, 1988 PubMed Europe PMC Scholia
  103. G. Valle, G. Faulkner, A. De Antoni, B. Pacchioni, A. Pallavicini, D. Pandolfo, N. Tiso, S. Toppo, S. Trevisan, G. Lanfranchi; ''Telethonin, a novel sarcomeric protein of heart and skeletal muscle.''; , 1997 PubMed Europe PMC Scholia
  104. M. Streuli, L. R. Hall, Y. Saga, S. F. Schlossman, H. Saito; ''Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens''; WikiPathway, 1987 PubMed Europe PMC Scholia
  105. T. Ohbayashi, K. Oikawa, R. Iwata, A. Kameta, K. Evine, T. Isobe, Y. Matsuda, J. Mimura, Y. Fujii-Kuriyama, M. Kuroda, K. Mukai; ''Dioxin induces a novel nuclear factor, DIF-3, that is implicated in spermatogenesis.''; , 2001 PubMed Europe PMC Scholia
  106. E. B. Carson-Walter, D. N. Watkins, A. Nanda, B. Vogelstein, K. W. Kinzler, B. St. Croix; ''Cell surface tumor endothelial markers are conserved in mice and humans''; , 2001 PubMed Europe PMC Scholia
  107. Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H.[...], Sugano S.; ''Complete sequencing and characterization of 21,243 full-length human cDNAs.''; , 2004
  108. J. D. Schulman, S. I. Goodman, J. W. Mace, A. D. Patrick, F. Tietze, E. J. Butler; ''Glutathionuria: inborn error of metabolism due to tissue deficiency of gamma-glutamyl transpeptidase''; WikiPathway, 1975 PubMed Europe PMC Scholia
  109. Martin F. Orth, Alex Cazes, Elke Butt, Thomas G. P. Grunewald; '' An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein''; , 2015 PubMed Europe PMC Scholia
  110. H. Kubota, G. M. Hynes, S. M. Kerr, K. R. Willison; ''Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1.''; , 1997 PubMed Europe PMC Scholia
  111. Robert Liefke, Violett Karwacki-Neisius, Yang Shi; ''EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape''; , 2016 PubMed Europe PMC Scholia
  112. Marc D. Basson, Qinggang Wang, Lakshmi S. Chaturvedi, Shyam More, Emilie E. Vomhof-DeKrey, Sarmad Al-Marsoummi, Kelian Sun, Leslie A. Kuhn, Pavlo Kovalenko, Matti Kiupel; ''Schlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation.''; , 2018 PubMed Europe PMC Scholia
  113. Masuko Katoh, Masaru Katoh; ''Identification and characterization of human ARHGAP23 gene in silico''; , 2004 PubMed Europe PMC Scholia
  114. Joanna Ciomborowsk, Wojciech Rosikiewicz, Damian Szklarczyk, Wojciech Makałowski, Izabela Makałowska; ''"Orphan" retrogenes in the human genome.''; , 2013 PubMed Europe PMC Scholia
  115. Paola Pisano, Valerio Di Carlo, Enrique Blanco, Paul Chammas, Pedro Vizán, Arantxa Gutiérrez, Sergi Aranda, Malte BeringerBernhard Payer, Michael Wierer, Luciano Di Croce; ''EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells''; , 2016 PubMed Europe PMC Scholia
  116. Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L.[...], Nusbaum C.; ''DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.''; UniProt, 2006 PubMed Europe PMC Scholia
  117. Laszlo Nagy, Roland Schüle, Hinrich Gronemeyer; ''Twenty years of nuclear receptors: Conference on Nuclear Receptors: from Chromatin to Disease''; WikiPathways, 2006 PubMed Europe PMC Scholia
  118. T. A. Donlon, A. M. Krensky, M. R. Wallace, F. S. Collins, M. Lovett, C. Clayberger; ''Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12.''; , 1990
  119. Y. Zhu, C. Qi, S. Jain, M. M. Le Beau, R. Espinosa, G. B. Atkins, M. A. Lazar, A. V. Yeldandi, M. S. Rao, J. K. Reddy; ''Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer.''; , 1999 PubMed Europe PMC Scholia
  120. Yoshiko Murakami, Uamporn Siripanyapiny, Yeongjin Hong, Ji Young Kang, Sonoko Ishihara, Hideki Nakakuma, Yusuke Maeda, Taroh Kinoshita; ''PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor.''; , 2003 PubMed Europe PMC Scholia
  121. L. E. Rameh, K. F. Tolias, B. C. Duckworth, L. C. Cantley; ''A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate.''; , 1997 PubMed Europe PMC Scholia
  122. Ishida A., Asano H., Hasegawa M., Koseki H., Ono T., Yoshida M.C., Taniguchi M., Kanno M.; ''Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif.''; UniProt, 1993 PubMed Europe PMC Scholia
  123. Mariko Umemura, Michiyo Okamoto, Ken-ichi Nakayama, Koji Sagane, Kappei Tsukahara, Katsura Hata, Yoshifumi Jigami; ''GWT1 gene is required for inositol acylation of glycosylphosphatidylinositol anchors in yeast.''; , 2003 PubMed Europe PMC Scholia
  124. Lindfors K., Halttunen T., Huotari P., Nupponen N., Vihinen M., Visakorpi T., Maki M., Kainulainen H.; ''Identification of novel transcription factor-like gene from human intestinal cells.''; UniProt, 2000 PubMed Europe PMC Scholia
  125. M. D. Miller, S. D. Wilson, M. E. Dorf, H. N. Seuanez, S. J. O'Brien, M. S. Krangel; ''Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines''; , 1990 PubMed Europe PMC Scholia
  126. I. Bach, M. G. Mattei, S. Cereghini, M. Yaniv; ''''; ,
  127. Subhamoy Dasgupta, Ian Cushman, Marilyne Kpetemey, Patrick J. Casey, Jamboor K. Vishwanatha; ''Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis''; , 2011 PubMed Europe PMC Scholia
  128. William S. Modi; ''CCL3L1 and CCL4L1 chemokine genes are located in a segmental duplication at chromosome 17q12.''; , 2004 PubMed Europe PMC Scholia
  129. W Schmitz 1 , C Albers, R Fingerhut, E Conzelmann; ''Purification and characterization of an alpha-methylacyl-CoA racemase from human liver''; WikiPathways, 1995 PubMed Europe PMC Scholia
  130. Schulz-Knappe P., Maegert H.-J., Dewald B., Meyer M., Cetin Y., Kubbies M., Tomeczkowski J., Kirchhoff K., Raida M.[...],, Forssmann W.-G.; ''HCC-1, a novel chemokine from human plasma.''; UniProt, 1996 PubMed Europe PMC Scholia
  131. Hans R. Waterham, Sacha Ferdinandusse, Ronald J. A. Wanders; ''Human disorders of peroxisome metabolism and biogenesis''; WikiPathway, 2016 PubMed Europe PMC Scholia
  132. Yelena Bykhovskaya, Emebet Mengesha, Dai Wang, Huiying Yang, Xavier Estivill, Mordechai Shohat, Nathan Fischel-Ghodsian; ''Human mitochondrial transcription factor B1 as a modifier gene for hearing loss associated with the mitochondrial A1555G mutation''; WikiPathway, 2004 PubMed Europe PMC Scholia
  133. R. Waldmann, N. Voilley, M. G. Mattéï, M. Lazdunski; ''The human degenerin MDEG, an amiloride-sensitive neuronal cation channel, is localized on chromosome 17q11.2-17q12 close to the microsatellite D17S798''; , 1996 PubMed Europe PMC Scholia
  134. T. Druck, Y. Gu, G. Prabhala, L. A. Cannizzaro, S. H. Park, K. Huebner, J. H. Keen; ''Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP''; , 1995
  135. T. H. Lindner, P. R. Njolstad, Y. Horikawa, L. Bostad, G. I. Bell, O. Sovik; ''A novel syndrome of diabetes mellitus, renal dysfunction and genital malformation associated with a partial deletion of the pseudo-POU domain of hepatocyte nuclear factor-1beta.''; , 1999 PubMed Europe PMC Scholia
  136. D. M. Cimbora, M. Groudine; ''The control of mammalian DNA replication: a brief history of space and timing''; WikiPathway, 2001 PubMed Europe PMC Scholia
  137. R. Jason Lamontagne, Sumedha Bagga, Michael J. Bouchard; ''Hepatitis B virus molecular biology and pathogenesis''; WikiPathway, 2016 PubMed Europe PMC Scholia
  138. S. G. Irving, P. F. Zipfel, J. Balke, O. W. McBride, C. C. Morton, P. R. Burd, U. Siebenlist, K. Kelly; ''Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q.''; , 1990 PubMed Europe PMC Scholia
  139. Lars Hansen, Sophie Comyn, Yuan Mang, Allan Lind-Thomsen, Layne Myhre, Francesca Jean, Hans Eiberg, Niels Tommerup, Thomas Rosenberg, David Pilgrim; ''The myosin chaperone UNC45B is involved in lens development and autosomal dominant juvenile cataract.''; , 2014 PubMed Europe PMC Scholia
  140. Masuko Katoh, Masaru Katoh; ''Evolutionary recombination hotspot around GSDML-GSDM locus is closely linked to the oncogenomic recombination hotspot around the PPP1R1B-ERBB2-GRB7 amplicon.''; , 2004 PubMed Europe PMC Scholia
  141. M. Linnebank, F. Lagler, A. C. Muntau,, W. Röschinger, B. Olgemöller, B. Fowler, H. G. Koch; ''Methionine adenosyltransferase (MAT) I/III deficiency with concurrent hyperhomocysteinaemia: two novel cases''; WikiPathways, 2005 PubMed Europe PMC Scholia
  142. J. Lohi, C. L. Wilson, J. D. Roby, W. C. Parks; ''Epilysin, a novel human matrix metalloproteinase (MMP-28) expressed in testis and keratinocytes and in response to injury.''; , 2001 PubMed Europe PMC Scholia
  143. R. M. Tamimi, E. Steingrimsson, K. Montgomery-Dye, N. G. Copeland, N. A. Jenkins, S. J. Tapscott; ''NEUROD2 and NEUROD3 genes map to human chromosomes 17q12 and 5q23-q31 and mouse chromosomes 11 and 13, respectively.''; , 1997 PubMed Europe PMC Scholia
  144. A. Gallusser, T. Kirchhausen; ''The beta 1 and beta 2 subunits of the AP complexes are the clathrin coat assembly components''; , 1993 PubMed Europe PMC Scholia
  145. Anabelle Decottignies; ''Alternative end-joining mechanisms: a historical perspective''; WikiPathway, 2013 PubMed Europe PMC Scholia
  146. Bengt Persson, Yvonne Kallberg, James E. Bray, Elspeth Bruford, Stephen L. Dellaporta, Angelo D. Favia, Roser Gonzalez Duarte, Hans Jörnvall, Kathryn L. Kavanagh, Natalia Kedishvili, Michael Kisiela, Edmund Maser, Rebekka Mindnich, Sandra Orchard, Trevor M. Penning, Janet M. Thornton, Jerzy Adamski, Udo Oppermann; ''The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.''; , 2009 PubMed Europe PMC Scholia
  147. Miller M.D., Hata S., Waal Malefyt R., Krangel M.S.; ''A novel polypeptide secreted by activated human T lymphocytes.''; UniProt, 1989 PubMed Europe PMC Scholia
  148. Michael C Zody et al.; ''DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.''; , 2006
  149. Omar A. Quintero, Melinda M. DiVito, Rebecca C. Adikes, Melisa B. Kortan, Lindsay B. Case, Audun J. Lier, Niki S. Panaretos, Stephanie Q. Slater, Michelle Rengarajan, Marianela Feliu, Richard E. Cheney; ''Human Myo19 is a novel myosin that associates with mitochondria.''; , 2009 PubMed Europe PMC Scholia
  150. Li Y., Chen Z.; ''Molecular cloning and characterization of LCRG1 a novel gene localized to the tumor suppressor locus D17S800-D17S930.''; UniProt, 2004 PubMed Europe PMC Scholia
  151. Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., Ansorge W., Boecher M., Bloecker H., Bauersachs S.[...], Poustka A.; ''Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.''; UniProt, 2001 PubMed Europe PMC Scholia
  152. E. A. Garcia-Zepeda, M. E. Rothenberg, S. Weremowicz, M. N. Sarafi, C. C. Morton, A. D. Luster; ''Genomic organization, complete sequence, and chromosomal location of the gene for human eotaxin (SCYA11), an eosinophil-specific CC chemokine.''; , 1997 PubMed Europe PMC Scholia
  153. McCormick M.B., Tamimi R.M., Snider L., Asakura A., Bergstrom D., Tapscott S.J.; ''NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family.''; UniProt, 1996 PubMed Europe PMC Scholia
  154. N. Kaneda, H. Ichinose, K. Kobayashi, K. Oka, F. Kishi, A. Nakazawa, Y. Kurosawa, K. Fujita, T. Nagatsu; ''Molecular cloning of cDNA and chromosomal assignment of the gene for human phenylethanolamine N-methyltransferase, the enzyme for epinephrine biosynthesis.''; , 1988 PubMed Europe PMC Scholia
  155. Charles A. Paulding, Maryellen Ruvolo, Daniel A. Haber; ''The Tre2 (USP6) oncogene is a hominoid-specific gene.''; , 2003 PubMed Europe PMC Scholia
  156. S. Bokkala, S. S. el-Daher, V. V. Kakkar, F. Wuytack, K. S. Authi; ''Localization and identification of Ca2+ATPases in highly purified human platelet plasma and intracellular membranes. Evidence that the monoclonal antibody PL/IM 430 recognizes the SERCA 3 Ca2+ATPase in human platelets''; WikiPathway, 1995 PubMed Europe PMC Scholia
  157. Obaru K., Fukuda M., Maeda S., Shimada K.; ''A cDNA clone used to study mRNA inducible in human tonsillar lymphocytes by a tumor promoter.''; UniProt, 1986 PubMed Europe PMC Scholia
  158. M. F. Sardinia, J. M. Hanesworth, F. Krishnan, J. W. Harding; ''AT4 receptor structure-binding relationship: N-terminal-modified angiotensin IV analogues''; , 1994 PubMed Europe PMC Scholia
  159. Wong MM, Fish EN; ''Chemokines: attractive mediators of the immune response.''; Pathway, 2003 PubMed Europe PMC Scholia
  160. M Fanciulli 1 , T Bruno, M Di Padova, R De Angelis, S Iezzi, C Iacobini, A Floridi, C Passananti; ''Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb.''; , 2000 PubMed Europe PMC Scholia
  161. Kenneth R. Feingold, et al.; ''Introduction to Lipids and Lipoproteins''; WikiPathway, 2000 PubMed Europe PMC Scholia
  162. Patrizia Fabrizio, Julia Dannenberg, Prakash Dube, Berthold Kastner, Holger Stark, Henning Urlaub, Reinhard Lührmann; ''The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome.''; , 2009 PubMed Europe PMC Scholia
  163. Evangelos Mavrommatis, Eleanor N. Fish, Leonidas C. Platanias; ''The schlafen family of proteins and their regulation by interferons.''; ,
  164. B Morgan, L Sun, N Avitahl, K. Andrikopoulos, T. Ikeda, E. Gonzales, P. Wu, S. Neben, K. Georgopoulos; ''Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation.''; , 1997 PubMed Europe PMC Scholia
  165. Colobran R., Adreani P., Ashhab Y., Llano A., Este J.A., Dominguez O., Pujol-Borrell R., Juan M.; ''Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIV+ patients.''; UniProt, 2005 PubMed Europe PMC Scholia
  166. Lihe Chen, Hongyu Wu, Oleh M. Pochynyuk, Mary Rose Reisenauer, Zhijing Zhang, Le Huang, Oleg Leonidovych Zaika, Mykola Mamenko, Weiru Zhang, Qiaoling Zhou, Mingyao Liu, Yang Xia, Wenzheng Zhang; ''Af17 deficiency increases sodium excretion and decreases blood pressure.''; , 2011 PubMed Europe PMC Scholia
  167. Martin van der Laan, Dana P. Hutu, Peter Rehling; ''On the mechanism of preprotein import by the mitochondrial presequence translocase''; WikiPathways, 2010 PubMed Europe PMC Scholia
  168. L. Stryer, H. R. Bourne; ''G proteins: a family of signal transducers''; WikiPathway, 1986 PubMed Europe PMC Scholia
  169. Elizabeth E. Evans, Alicia D. Henn, Alan Jonason, Mark J. Paris, Linda M. Schiffhauer, Melinda A. Borrello, Ernest S. Smith, Deepak M. Sahasrabudh, Maurice Zauderer; ''C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer''; , 2006 PubMed Europe PMC Scholia
  170. Karl Walter Bock; ''From differential induction of UDP-glucuronosyltransferases in rat liver to characterization of responsible ligand-activated transcription factors, and their multilevel crosstalk in humans''; WikiPathways, 2011 PubMed Europe PMC Scholia
  171. Shiuh-Wen Luoh, Natarajan Venkatesan, Reshimi Tripathi; ''Overexpression of the amplified Pip4k2beta gene from 17q11-12 in breast cancer cells confers proliferation advantage''; , 2004 PubMed Europe PMC Scholia
  172. S. Brené, N. Lindefors, M. Ehrlich, T. Taubes, A. Horiuchi, J. Kopp, H. Hall, G. Sedvall, P. Greengard, H. Persson; ''Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue.''; , 1994 PubMed Europe PMC Scholia
  173. Powers P.A., Liu S., Hogan K., Gregg R.G.; ''Skeletal muscle and brain isoforms of a beta-subunit of human voltage- dependent calcium channels are encoded by a single gene.''; UniProt, 1992 PubMed Europe PMC Scholia
  174. R. Prasad, D. Leshkowitz, Y. Gu, H. Alder, T. Nakamura, H. Saito, K. Huebner, R. Berger, C. M. Croce, E. Canaani; ''Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia.''; , 1994 PubMed Europe PMC Scholia
  175. Rebecca L. Plimpton, Jorge Cuéllar, Chun Wan J. Lai, Takuma Aoba, Aman Makaju, Sarah Franklin, Andrew D. Mathis, John T. Prince, José L. Carrascosa, José M. Valpuesta, Barry M. Willardson; ''Structures of the Gβ-CCT and PhLP1-Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly''; WikiPathway, 2015 PubMed Europe PMC Scholia
  176. Nezu M., Nishigaki M., Ishizuka T., Kuwahara Y., Tanabe C., Aoyagi K., Sakamoto H., Saito Y., Yoshida T.[...], Terada M.; ''Identification of the CAB2/hCOS16 gene required for the repair of DNA double-strand breaks on a core amplified region of the 17q12 locus in breast and gastric cancers.''; UniProt, 2002 PubMed Europe PMC Scholia
  177. Garcia-Zepeda E.A., Combadiere C., Rothenberg M.E., Sarafi M.N., Lavigne F., Hamid Q., Murphy P.M., Luster A.D.; ''Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3.''; Uniprot, 1996 PubMed Europe PMC Scholia
  178. Luis Sanchez-Pulido, Chris P. Ponting; ''TMEM132: an ancient architecture of cohesin and immunoglobulin domains define a new family of neural adhesion molecules.''; ,

History

View all...
CompareRevisionActionTimeUserComment
126824view11:19, 25 June 2023EgonwConverted graphical lines to be that in the GPML too
126823view11:11, 25 June 2023EgonwModified description
124559view16:10, 8 November 2022FehrhartOntology Term : 'disease pathway' added !
124461view07:51, 29 October 2022EgonwMade four more pathways clickable
124350view05:08, 19 October 2022EgonwRemoved whitespace in the pubmed id
124349view05:05, 19 October 2022EgonwMade many pathways clickable
124187view04:40, 26 September 2022EgonwUpdated the UniProt data sources
124184view12:25, 25 September 2022JulietaCostaNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
SLFN14GeneProductENSG00000236320 (Ensembl)
39S ribosomal

protein L45,

mitochondrial		ProteinQ9BRJ2 (Uniprot-TrEMBL)
60S ribosomal protein L23ProteinP62829 (Uniprot-TrEMBL)
AATFGeneProductENSG00000275700 (Ensembl)
ACACAGeneProductENSG00000278540 (Ensembl)
AP-2 complex subunit betaProteinP63010 (Uniprot-TrEMBL)
AP2B1GeneProductENSG00000006125 (Ensembl)
ARHGAP23GeneProductENSG00000275832 (Ensembl)
ARL5CGeneProductENSG00000141748 (Ensembl)
ASIC2 GeneProductENSG00000108684 (Ensembl) Chromosomal Location 17q11.2-q12
Acetyl-CoA carboxylase 1 ProteinQ13085 (Uniprot-TrEMBL)
Acid-sensing ion channel 2ProteinQ16515 (Uniprot-TrEMBL) Cation channel with high affinity for sodium
Brain-derived

neurotrophic factor (BDNF) signaling

pathway		PathwayWP2380 (WikiPathways)
Brain-derived

neurotrophic factor

(BDNF) signaling pathway		PathwayWP2380 (WikiPathways)
C-C motif chemokine 13ProteinQ99616 (Uniprot-TrEMBL)
C-C motif chemokine 14ProteinQ16627 (Uniprot-TrEMBL)
C-C motif chemokine 15ProteinQ16663 (Uniprot-TrEMBL)
C-C motif chemokine 16 ProteinO15467 (Uniprot-TrEMBL)
C-C motif chemokine 18ProteinP55774 (Uniprot-TrEMBL)
C-C motif chemokine 1ProteinP22362 (Uniprot-TrEMBL)
C-C motif chemokine 2ProteinP13500 (Uniprot-TrEMBL) Biological process: Inflammatory response & Chemotaxis
C-C motif chemokine 3-like 1ProteinP16619 (Uniprot-TrEMBL)
C-C motif chemokine 3ProteinP10147 (Uniprot-TrEMBL)
C-C motif chemokine 4-like ProteinQ8NHW4 (Uniprot-TrEMBL)
C-C motif chemokine 4ProteinP13236 (Uniprot-TrEMBL)
C-C motif chemokine 5 ProteinP13501 (Uniprot-TrEMBL)
C-C motif chemokine 7ProteinP80098 (Uniprot-TrEMBL)
C-C motif chemokine 8ProteinP80075 (Uniprot-TrEMBL)
C17orf50GeneProductENSG00000270806 (Ensembl)
C17orf78 GeneProductENSG00000278505 (Ensembl)
C17orf98GeneProductENSG00000275489 (Ensembl)
CACNB1GeneProductENSG00000067191 (Ensembl)
CCL11 GeneProductENSG00000172156 (Ensembl)
CCL13GeneProductENSG00000181374 (Ensembl)
CCL14GeneProductENSG00000276409 (Ensembl)
CCL15GeneProductENSG00000275718 (Ensembl)
CCL16GeneProductENSG00000275152 (Ensembl)
CCL18GeneProductENSG00000275385 (Ensembl)
CCL1GeneProductENSG00000108702 (Ensembl)
CCL2GeneProductENSG00000108691 (Ensembl)
CCL3GeneProductENSG00000277632 (Ensembl)
CCL3L1GeneProductENSG00000276085 (Ensembl)
CCL4GeneProductENSG00000275302 (Ensembl)
CCL4L2GeneProductENSG00000276070 (Ensembl)
CCL5GeneProductENSG00000271503 (Ensembl)
CCL7GeneProductENSG00000108688 (Ensembl)
CCL8GeneProductENSG00000108700 (Ensembl)
CCT6BGeneProductENSG00000132141 (Ensembl)
CDGSH iron-sulfur

domain-containing

protein 3, mitochondrial 		ProteinP0C7P0 (Uniprot-TrEMBL)
CDK12GeneProductENSG00000167258 (Ensembl)
CISD3GeneProductENSG00000277972 (Ensembl)
CWC25GeneProductENSG00000273559 (Ensembl)
Chemokine

Signaling

Pathway		PathwayWP3929 (WikiPathways)
Class I peroxisomal

membrane protein

import		PathwayWP4987 (WikiPathways)
Costimulation

by the

CD28 family		PathwayWP1799 (WikiPathways)
Cyclin-dependent kinase 12 ProteinQ9NYV4 (Uniprot-TrEMBL)
DDX52GeneProductENSG00000278053 (Ensembl)
DHRS11GeneProductENSG00000278535 (Ensembl)
DNA Repair PathwaysPathwayWP4946 (WikiPathways)
DNA ReplicationPathwayWP466 (WikiPathways)
DNA ligase 3 ProteinP49916 (Uniprot-TrEMBL)
DNA repair protein RAD51 homolog 4ProteinO75771 (Uniprot-TrEMBL)
DUSP14GeneProductENSG00000276023 (Ensembl)
Degradation of

beta-catenin by the destruction

complex 		PathwayWP2773 (WikiPathways)
Dehydrogenase/

reductase

SDR family member 11		ProteinQ6UWP2 (Uniprot-TrEMBL)
Dual specificity

protein

phosphatase 14		ProteinO95147 (Uniprot-TrEMBL)
E3 ubiquitin

ligases ubiquitinate

target proteins		PathwayWP4055 (WikiPathways)
E3 ubiquitin-protein ligase rififylinProteinQ8WZ73 (Uniprot-TrEMBL)
EGFR tyrosine

kinase inhibitor

resistance		PathwayWP4806 (WikiPathways)
EPOPGeneProductENSG00000273604 (Ensembl)
ERBB2GeneProductENSG00000141736 (Ensembl)
Elongin BC and Polycomb

repressive complex 2-associated

protein		ProteinA6NHQ4 (Uniprot-TrEMBL)
EotaxinProteinP51671 (Uniprot-TrEMBL)
F-box only protein 47ProteinQ5MNV8 (Uniprot-TrEMBL)
F-box/LRR- repeat protein 20ProteinQ96IG2 (Uniprot-TrEMBL)
FBXL20GeneProductENSG00000108306 (Ensembl)
FBXO47GeneProductENSG00000204952 (Ensembl)
FNDC8GeneProductENSG00000073598 (Ensembl)
Factors and pathways

affecting insulin-like growth factor (IGF1)-Akt

signaling		PathwayWP3850 (WikiPathways)
Familial

Hyperlipidemia

type 1		PathwayWP5108 (WikiPathways)
Familial

Hyperlipidemia

type 3 		PathwayWP5110 (WikiPathways)
Fibronectin type III

domain-containing

protein 8		ProteinQ8TC99 (Uniprot-TrEMBL)
G protein

signaling

pathways		PathwayWP35 (WikiPathways)
G-protein beta gamma signalingPathwayWP4428 (WikiPathways)
GAS2-like protein 2ProteinQ8NHY3 (Uniprot-TrEMBL)
GAS2L2GeneProductENSG00000270765 (Ensembl)
GGNBP2GeneProductENSG00000278311 (Ensembl)
GPR179GeneProductENSG00000277399 (Ensembl)
GRB7GeneProductENSG00000141738 (Ensembl)
Gametogenetin-binding protein 2ProteinQ9H3C7 (Uniprot-TrEMBL)
Gamma-glutamyl

cycle for the biosynthesis and degradation of glutathione,

including diseases		PathwayWP4518 (WikiPathways)
GeneGeneProduct
Growth factor receptor-bound protein 7 ProteinQ14451 (Uniprot-TrEMBL)
HEATR9GeneProductENSG00000270379 (Ensembl)
HNF1BGeneProductENSG00000275410 (Ensembl)
Hepatitis B infectionPathwayWP4666 (WikiPathways)
Hepatocyte growth factor receptor signalingPathwayWP313 (WikiPathways)
Hepatocyte nuclear factor 1-betaProteinP35680 (Uniprot-TrEMBL)
Host

Interactions

of HIV factors		PathwayWP2684 (WikiPathways)
IKZF3GeneProductENSG00000161405 (Ensembl)
Interactome of

polycomb repressive

complex 2 (PRC2)		PathwayWP2916 (WikiPathways)
Ion Channel Transport PathwayWP4098 (WikiPathways)
LASP1GeneProductENSG00000002834 (Ensembl)
LHX1GeneProductENSG00000273706 (Ensembl)
LIG3GeneProductENSG00000005156 (Ensembl)
LIM and SH3 domain protein 1 ProteinQ14847 (Uniprot-TrEMBL)
LIM/homeobox protein Lhx1 ProteinP48742 (Uniprot-TrEMBL)
LYZL6GeneProductENSG00000275722 (Ensembl)
Lysozyme-like protein 6 ProteinO75951 (Uniprot-TrEMBL)
MED1GeneProductENSG00000125686 (Ensembl)
MIEN1GeneProductENSG00000141741 (Ensembl)
MLLT6GeneProductENSG00000275023 (Ensembl)
MMP28GeneProductENSG00000271447 (Ensembl)
MRM1GeneProductENSG00000278619 (Ensembl)
MRPL45GeneProductENSG00000278845 (Ensembl)
MYO19GeneProductENSG00000278259 (Ensembl)
Matrix metalloproteinase-28ProteinQ9H239 (Uniprot-TrEMBL)
Mediator of RNA polymerase II transcription subunit 1 ProteinQ15648 (Uniprot-TrEMBL)
Methionine metabolism

leading to sulfur amino

acids and related disorders		PathwayWP4292 (WikiPathways)
Migration and invasion enhancer 1ProteinQ9BRT3 (Uniprot-TrEMBL)
Mitochondrial

iron-sulfur

cluster biogenesis 		PathwayWP2702 (WikiPathways)
Mitochondrial protein importPathwayWP2717 (WikiPathways)
NEUROD2GeneProductENSG00000171532 (Ensembl)
NLE1GeneProductENSG00000073536 (Ensembl)
NRF2 pathway PathwayWP2884 (WikiPathways)
Neurogenic differentiation factor 2ProteinQ15784 (Uniprot-TrEMBL)
Notchless protein homolog 1 ProteinQ9NVX2 (Uniprot-TrEMBL)
Nuclear receptorsPathwayWP170 (WikiPathways)
PCGF2GeneProductENSG00000277258 (Ensembl)
PEX12GeneProductENSG00000108733 (Ensembl)
PGAP3GeneProductENSG00000161395 (Ensembl)
PIGWGeneProductENSG00000277161 (Ensembl)
PIP4K2BGeneProductENSG00000276293 (Ensembl)
PLXDC1GeneProductENSG00000161381 (Ensembl)
PNMTGeneProductENSG00000141744 (Ensembl)
PPP1R1BGeneProductENSG00000131771 (Ensembl)
PathwayPathway
Peroxisomal lipid metabolismPathwayWP1878 (WikiPathways)
Peroxisomal protein import PathwayWP4442 (WikiPathways)
Peroxisome assembly protein 12ProteinO00623 (Uniprot-TrEMBL)
Phenylethanolamine N-methyltransferase ProteinP11086 (Uniprot-TrEMBL)
Phosphatidylinositol

5-phosphate 4-kinase

type-2 beta		ProteinP78356 (Uniprot-TrEMBL)
Phosphatidylinositol-glycan biosynthesis class W proteinProteinQ7Z7B1 (Uniprot-TrEMBL)
Plexin

domain-containing

protein 1 		ProteinQ8IUK5 (Uniprot-TrEMBL)
Polycomb group RING finger protein 2ProteinP35227 (Uniprot-TrEMBL)
Post-GPI attachment to proteins factor 3 ProteinQ96FM1 (Uniprot-TrEMBL)
Pre-mRNA-splicing factor CWC25 homolog ProteinQ9NXE8 (Uniprot-TrEMBL)
Presynaptic

depolarization and calcium

channel opening		PathwayWP1800 (WikiPathways)
Probable

ATP-dependent

RNA helicase DDX52		ProteinQ9Y2R4 (Uniprot-TrEMBL)
Probable G-protein coupled receptor 179ProteinQ6PRD1 (Uniprot-TrEMBL)
Prolactin receptor signalingPathwayWP2678 (WikiPathways)
ProteinProtein
Protein FoldingPathwayWP1892 (WikiPathways) Interact with molecular chaperones to attain their native conformation.
Protein AATF ProteinQ9NY61 (Uniprot-TrEMBL)
Protein AF-17ProteinP55198 (Uniprot-TrEMBL)
Protein HEATR9ProteinA2RTY3 (Uniprot-TrEMBL)
Protein SLFN14ProteinP0C7P3 (Uniprot-TrEMBL)
Protein phosphatase 1 regulatory subunit 1BProteinQ9UD71 (Uniprot-TrEMBL)
Protein unc-45 homolog BProteinQ8IWX7 (Uniprot-TrEMBL)
Putative

ADP-ribosylation

factor-like protein 5C		ProteinA6NH57 (Uniprot-TrEMBL)
RAD51D GeneProductENSG00000185379 (Ensembl)
RAD52

motif-containing

protein 1		ProteinQ8NG50 (Uniprot-TrEMBL)
RAF/MAP kinase cascadePathwayWP2735 (WikiPathways)
RASL10BGeneProductENSG00000270885 (Ensembl)
RDM1GeneProductENSG00000278023 (Ensembl)
RFFLGeneProductENSG00000092871 (Ensembl)
RNA Polymerase II TranscriptionPathwayWP1906 (WikiPathways)
RPL23GeneProductENSG00000125691 (Ensembl)
Ras-like protein family member 10BProteinQ96S79 (Uniprot-TrEMBL)
Receptor

tyrosine-protein

kinase erbB-2		ProteinP04626 (Uniprot-TrEMBL)
Rho GTPase-activating protein 23ProteinQ9P227 (Uniprot-TrEMBL)
Ribonuclease SLFN12ProteinQ8IYM2 (Uniprot-TrEMBL)
SH3 and cysteine-rich domain-containing protein 2 ProteinQ6ZMT1 (Uniprot-TrEMBL)
SLC35G3GeneProductENSG00000164729 (Ensembl)
SLFN11GeneProductENSG00000172716 (Ensembl)
SLFN12GeneProductENSG00000172123 (Ensembl)
SLFN13GeneProductENSG00000154760 (Ensembl)
SLFN5GeneProductENSG00000166750 (Ensembl)
SOCS7GeneProductENSG00000274211 (Ensembl)
SRC kinase signaling inhibitor 1ProteinQ9C0H9 (Uniprot-TrEMBL)
SRCIN1GeneProductENSG00000277363 (Ensembl)
STAC2GeneProductENSG00000141750 (Ensembl)
STARD3GeneProductENSG00000131748 (Ensembl)
SYNRGGeneProductENSG00000275066 (Ensembl)
Schlafen family member 13ProteinQ68D06 (Uniprot-TrEMBL)
Schlafen family member 11ProteinQ7Z7L1 (Uniprot-TrEMBL)
Schlafen family member 5ProteinQ08AF3 (Uniprot-TrEMBL)
Solute carrier family 35 member G3ProteinQ8N808 (Uniprot-TrEMBL)
StAR-related lipid transfer protein 3 ProteinQ14849 (Uniprot-TrEMBL)
Suppressor of cytokine signaling 7 ProteinO14512 (Uniprot-TrEMBL)
Synergin gammaProteinQ9UMZ2 (Uniprot-TrEMBL)
T-complex protein 1 subunit zeta-2 ProteinQ92526 (Uniprot-TrEMBL)
TADA2AGeneProductENSG00000276234 (Ensembl)
TAF15GeneProductENSG00000270647 (Ensembl)
TATA-binding

protein-associated

factor 2N		ProteinQ92804 (Uniprot-TrEMBL)
TBC1 domain family member 3BProteinA6NDS4 (Uniprot-TrEMBL)
TBC1 domain family member 3CProteinQ6IPX1 (Uniprot-TrEMBL)
TBC1 domain family member 3G ProteinQ6DHY5 (Uniprot-TrEMBL)
TBC1 domain family member 3HProteinP0C7X1 (Uniprot-TrEMBL)
TBC1 domain family member 3IProteinA0A087WXS9 (Uniprot-TrEMBL)
TBC1 domain family member 3KProteinA0A087X1G2 (Uniprot-TrEMBL)
TBC1 domain family member 3LProteinB9A6J9 (Uniprot-TrEMBL)
TBC1 domain family member 3ProteinQ8IZP1 (Uniprot-TrEMBL)
TBC1D3BGeneProductENSG00000274808 (Ensembl)
TBC1D3CGeneProductENSG00000278299 (Ensembl)
TBC1D3GeneProductENSG00000274611 (Ensembl)
TBC1D3GGeneProductENSG00000260287 (Ensembl)
TBC1D3HGeneProductENSG00000274226 (Ensembl)
TBC1D3IGeneProductENSG00000274933 (Ensembl)
TBC1D3KGeneProductENSG00000273513 (Ensembl)
TBC1D3LGeneProductENSG00000274512 (Ensembl)
TCAPGeneProductENSG00000173991 (Ensembl)
TECGeneProductENSG00000279119 (Ensembl)
  • This gene does not contain any transcripts
  • Type your comment here
TLK2P1 GeneProductENSG00000226049 (Ensembl) Also known as: HUAT, LGALS9A
TMEM132E-DTProteinA2RUQ5 (Uniprot-TrEMBL)
  • Uncharacterized protein
  • Type your comment here
TMEM132E-DTGeneProductENSG00000197322 (Ensembl)
TMEM132EGeneProductENSG00000181291 (Ensembl)
Telethonin ProteinO15273 (Uniprot-TrEMBL)
Transcriptional adapter 2-alphaProteinO75478 (Uniprot-TrEMBL)
Transmembrane protein 132EProteinQ6IEE7 (Uniprot-TrEMBL)
Tyrosine-protein kinase Tec ProteinP42680 (Uniprot-TrEMBL)
UNC45BGeneProductENSG00000141161 (Ensembl)
Uncharacterized protein C17orf50ProteinQ8WW18 (Uniprot-TrEMBL)
Uncharacterized protein C17orf78 ProteinQ8N4C9 (Uniprot-TrEMBL)
Uncharacterized protein C17orf98ProteinA8MV24 (Uniprot-TrEMBL)
Unconventional myosin-XIXProteinQ96H55 (Uniprot-TrEMBL)
Voltage-dependent

L-type calcium

channel subunit beta-1		ProteinQ02641 (Uniprot-TrEMBL)
ZNF830GeneProductENSG00000198783 (Ensembl)
ZNHIT3GeneProductENSG00000273611 (Ensembl)
Zinc finger protein 830 ProteinQ96NB3 (Uniprot-TrEMBL)
Zinc finger HIT

domain-containing

protein 3		ProteinQ15649 (Uniprot-TrEMBL)
Zinc finger protein Aiolos ProteinQ9UKT9 (Uniprot-TrEMBL)
p53 transcriptional gene networkPathwayWP4963 (WikiPathways)
rRNA

methyltransferase

1, mitochondrial 		ProteinQ6IN84 (Uniprot-TrEMBL)
rRNA modification in the mitochondrionPathwayWP4099 (WikiPathways)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5287"
Personal tools