Wnt/Beta-catenin signaling inhibitors in current and past clinical trials (Homo sapiens)
From WikiPathways
Description
Wnt/Beta-catenin signaling inhibitors in current and past clinical trials
Quality Tags
Ontology Terms
Pathway Ontology : cell cycle pathway, mitotic
Bibliography
- Jung YS, Park JI; ''Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex.''; Exp Mol Med, 2020 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name ![]() | Type ![]() | Database reference ![]() | Comment ![]() |
---|---|---|---|
APC | GeneProduct | ||
AXIN | GeneProduct | ||
CBP | GeneProduct | Q92793 (Uniprot-TrEMBL) ![]() | |
CGX-1321 | Metabolite | Q124448546 (Wikidata) ![]() | |
CK1 | GeneProduct | ||
CTNNB1 | GeneProduct | ENSG00000168036 (Ensembl) ![]() | |
DVL | GeneProduct | ||
ETC-1922159 | Metabolite | Q124448578 (Wikidata) ![]() | |
Frizzled | Protein | IPR000539 (InterPro) ![]() | |
GSK3 | GeneProduct | ||
LRP5 | GeneProduct | ENSG00000162337 (Ensembl) ![]() | |
LRP6 | GeneProduct | ENSG00000070018 (Ensembl) ![]() | |
OMP-18R5 | Metabolite | Q7915216 (Wikidata) ![]() | |
OMP-54f28 | Metabolite | Q124625115 (Wikidata) ![]() | |
OTSA101-DTPA-90Y | Metabolite | Q124449028 (Wikidata) ![]() | |
PORCN | GeneProduct | ENSG00000102312 (Ensembl) ![]() | |
PRI 724 | Metabolite | Q123515698 (Wikidata) ![]() | |
RXC004 | Metabolite | Q124439695 (Wikidata) ![]() | |
SM08502 | Metabolite | Q124448796 (Wikidata) ![]() | |
TCF | GeneProduct | ||
WNT-974 | Metabolite | 46926973 (PubChem-compound) ![]() | |
WNT | GeneProduct | IPR005817 (InterPro) ![]() |
Annotated Interactions
No annotated interactions