Cirgarette Smoke Induced Lung Fibrosis (Homo sapiens)

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Collagen biosynthesisand modifying enzymesIncrease of ROSRegenerationandnormal lung functionGrowth factor releaseOverview ofinflammatory mediatorsLung epthelial cellsOxidative stress and ROSNF-kB pathwayIncreased activation of Nuclear factor kappa B (NF-kB)FibrosisCigarette smoke exposureRelease ofpro-inflammatory mediatorsCollagen accumulation


Description

Chronic cigarette smoke exposure induced lung fibrosis

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History

CompareRevisionActionTimeUserComment
129158view09:53, 13 March 2024BurritacoNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
Cigarette smoke exposure
Collagen accumulation68 (Other)
Collagen biosynthesis

and

modifying enzymes
PathwayWP2725 (WikiPathways)
Fibrosis1276 (Other)
Growth factor release
Increase of ROS
Increased activation

of

Nuclear factor kappa B 
(NF-kB)
Complex1172 (Other)
Lung epthelial cells
NF-kB pathwayPathwayWP4562 (WikiPathways)
Overview of

inflammatory

mediators
PathwayWP5095 (WikiPathways)
Oxidative stress

and

ROS
PathwayWP554 (WikiPathways)
Regeneration

and

normal lung function
Release of

pro-inflammatory

mediators
1469 (Other)

Annotated Interactions

No annotated interactions

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