Substance interaction with the pulmonary resident cell membrane components leading to pulmonary fibrosis - Carbon Nanotubes (Homo sapiens)

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Pulmonary fibrosisMetabolic pathways of fibroblastsIncreased, recruitment of inflammatory cells Increased, activation of T (T) helper (h) type 2 cellsIncreased, secretion of proinflammatory mediatorsActivation of Th2 cellsSubstance interaction with lung cells Increased, fibroblast proliferation and myofibroblast differentiation Loss of alveolar capillary membrane integrityAccumulation, CollagenInflammatory cytokines


Description

Pulmorary Fibrosis

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History

CompareRevisionActionTimeUserComment
129159view09:56, 13 March 2024SamBrussNew pathway

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DataNodes

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NameTypeDatabase referenceComment
Increased, activation of T (T) helper (h) type 2 cells
Increased, fibroblast proliferation and myofibroblast differentiation
Loss of alveolar capillary membrane integrity
Accumulation, Collagen
Activation of Th2 cellsPathwayWP1011 (WikiPathways)
Increased, recruitment of inflammatory cells
Increased, secretion of proinflammatory mediators
Inflammatory cytokinesPathwayWP5095 (WikiPathways)
Metabolic pathways of fibroblastsPathwayWP5312 (WikiPathways)
Pulmonary fibrosis
Substance interaction with lung cells

Annotated Interactions

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