From WikiPathways
ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Class I: EGFR EGFR ERBB2 ERBB3 ERBB4 Class II: Insulin R INSR IGFR Class III: PDGFR PDGFRA PDGFRB M-CSFR KIT Class IV: VEGFR VEGFR1 VEGFR2 VEGFR3 Class V: FGFR FGFR1 FGFR2 FGFR3 FGFR4 Class VI: CCK CCK4 Class VII: NGFR TRKA TRKB TRKC Class VIII: HGFR MET RON FLT3L Class IX: FGFR EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHB1 EPHB2 EPHB3 EPHB4 EPHB5 EPHB6 Class XI: TIE TIE TEK Class XII: RYK RYK Class XIII: DDR DDR1 DDR2 Class XIV: RET RET Class XV: ROS ROS Class XVI: LTK LTK ALK Class XVII: ROR ROR1 ROR2 Class XVIII: MUSK MUSK Class XX: MET RON MET RON Class XIX: LMR Class X: AXL EGFR ERBB2 ERBB3 AATYK1 AATYK2 AATYK3 Name: Receptor tyrosine kinase (RTK) family Organism: Homo sapiens
Description
An annotated list of receptor tyrosine kinase (RTK) genes
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Quality Tags
Approved version The current version of this pathway was approved for data analysis by Eric Weitz .
Annotated lists Annotated lists of gene products are considered useful for analysis and for stimulating future pathway curation.
Ontology Terms
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Bibliography
Ségaliny AI, Tellez-Gabriel M, Heymann MF, Heymann D; ''Receptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancers.''; J Bone Oncol, 2015 PubMed Europe PMC Scholia
History
External references
DataNodes
Name Type Database reference Comment AATYK1 GeneProduct AATYK2 GeneProduct AATYK3 GeneProduct ALK GeneProduct CCK4 GeneProduct DDR1 GeneProduct DDR2 GeneProduct EGFR GeneProduct EPHA1 GeneProduct EPHA2 GeneProduct EPHA3 GeneProduct EPHA4 GeneProduct EPHA5 GeneProduct EPHA6 GeneProduct EPHB1 GeneProduct EPHB2 GeneProduct EPHB3 GeneProduct EPHB4 GeneProduct EPHB5 GeneProduct EPHB6 GeneProduct ERBB2 GeneProduct ERBB3 GeneProduct ERBB4 GeneProduct FGFR1 GeneProduct FGFR2 GeneProduct FGFR3 GeneProduct FGFR4 GeneProduct FLT3L GeneProduct IGFR GeneProduct INSR GeneProduct KIT GeneProduct LTK GeneProduct M-CSFR GeneProduct MET GeneProduct MUSK GeneProduct PDGFRA GeneProduct PDGFRB GeneProduct RET GeneProduct RON GeneProduct ROR1 GeneProduct ROR2 GeneProduct ROS GeneProduct RYK GeneProduct TEK GeneProduct TIE GeneProduct TRKA GeneProduct TRKB GeneProduct TRKC GeneProduct VEGFR1 GeneProduct VEGFR2 GeneProduct VEGFR3 GeneProduct
Annotated Interactions
No annotated interactions