HSPB3 (Homo sapiens)

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Description

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Ontology Terms

Bibliography

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1. Suzuki A, Sugiyama Y, Hayashi Y, Nyu-i N, Yoshida M, Nonaka I, Ishiura S, Arahata K, Ohno S; ''MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase.''; J Cell Biol, 1998 PubMed Europe PMC Scholia
2. Gagan J, Dey BK, Layer R, Yan Z, Dutta A; ''Notch3 and Mef2c proteins are mutually antagonistic via Mkp1 protein and miR-1/206 microRNAs in differentiating myoblasts.''; J Biol Chem, 2012 PubMed Europe PMC Scholia
3. Fan JY, Rangasamy D, Luger K, Tremethick DJ; ''H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber folding.''; Mol Cell, 2004 PubMed Europe PMC Scholia
4. Hayashihara K, Uchiyama S, Shimamoto S, Kobayashi S, Tomschik M, Wakamatsu H, No D, Sugahara H, Hori N, Noda M, Ohkubo T, Zlatanova J, Matsunaga S, Fukui K; ''The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNA.''; J Biol Chem, 2010 PubMed Europe PMC Scholia
5. Solovei I, Wang AS, Thanisch K, Schmidt CS, Krebs S, Zwerger M, Cohen TV, Devys D, Foisner R, Peichl L, Herrmann H, Blum H, Engelkamp D, Stewart CL, Leonhardt H, Joffe B; ''LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation.''; Cell, 2013 PubMed Europe PMC Scholia
6. Ye Q, Worman HJ; ''Primary structure analysis and lamin B and DNA binding of human LBR, an integral protein of the nuclear envelope inner membrane.''; J Biol Chem, 1994 PubMed Europe PMC Scholia
7. Tiago T, Hummel B, Morelli FF, Basile V, Vinet J, Galli V, Mediani L, Antoniani F, Pomella S, Cassandri M, Garone MG, Silvestri B, Cimino M, Cenacchi G, Costa R, Mouly V, Poser I, Yeger-Lotem E, Rosa A, Alberti S, Rota R, Ben-Zvi A, Sawarkar R, Carra S; ''Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor.''; Cell Death Dis, 2021 PubMed Europe PMC Scholia
8. Sugiyama Y, Suzuki A, Kishikawa M, Akutsu R, Hirose T, Waye MM, Tsui SK, Yoshida S, Ohno S; ''Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation.''; J Biol Chem, 2000 PubMed Europe PMC Scholia
9. Ye Q, Callebaut I, Pezhman A, Courvalin JC, Worman HJ; ''Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR.''; J Biol Chem, 1997 PubMed Europe PMC Scholia

History

Compare	Revision	Action	Time	User	Comment
	138199	view	17:30, 24 March 2025	Oqbehm	Changed faulty HP1B3 protein name to HP1BP3
	138198	view	15:20, 24 March 2025	Oqbehm	MYOD directly increases NOTCH3 expression
	138164	view	15:08, 19 March 2025	Oqbehm	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
ACTA1	GeneProduct	P68133 (Uniprot-TrEMBL)
CBX5	Protein	P45973 (Uniprot-TrEMBL)	aka HP1 (heterochromatin protein 1)
DES	GeneProduct	P17661 (Uniprot-TrEMBL)
DMPK	Protein	Q09013 (Uniprot-TrEMBL)
H2AZ	Protein	P0C0S5 (Uniprot-TrEMBL)
HP1BP3	Protein	Q5SSJ5 (Uniprot-TrEMBL)	ad
HSPB2	Protein	Q16082 (Uniprot-TrEMBL)
HSPB3	Protein	Q12988 (Uniprot-TrEMBL)
LBR	Protein	Q14739 (Uniprot-TrEMBL)
LMNA	Protein	P02545 (Uniprot-TrEMBL)
LMNB1	Protein	P20700 (Uniprot-TrEMBL)
MEF2C	Protein	Q06413 (Uniprot-TrEMBL)
MYOD	Protein	P15172 (Uniprot-TrEMBL)
MYOG	GeneProduct	P15173 (Uniprot-TrEMBL)
NOTCH3	Protein	Q9UM47 (Uniprot-TrEMBL)
hsa-miR-1	Rna	ENSG00000199017 (Ensembl)
hsa-miR-206	Rna	ENSG00000207604 (Ensembl)

Annotated Interactions

No annotated interactions