Celiac disease mechanism and therapies (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Antigenpresenting cellLabelTolerance inductionMucus layerIntestinalepithelialcellInflammationTG2TAK-101GlutenIntestinal epithelialcellGluten-specificCD4 T cellGluten-specificCD4 TregGlutenpeptideDeaminatedglutenpeptideHLA-DQ2HLA-DQ8IL2IL21TNFAIFNGCD8 T cellLumenLamina propriaBlood streamCD4IFNGGZMBIL15KAN-101ZED1227GSK3915393AGYPTG-100LarazotideGlutenneutralizationTolerase GTAK-062LatiglutenaseGlutenasesTRATRBTeriflunomideCD4 T cell targetingPyrimidinesynthesisDHODHPRV-015CALY-002Anti-IL15 mAbLoss of toleranceEGFRPAR2ITGB7ITGA4Name: Celiac disease mechanism and therapiesOrganism: Homo sapiens


Description

No description

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Quality Tags

Image:UnderConstruction.pngUnder construction

Ontology Terms

Pathway Ontology : transcription pathway
 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
139368view10:10, 6 June 2025EweitzUpdate
139343view11:30, 3 June 2025EweitzClarify drug mechanism of inhibition loss of tolerance
139342view11:21, 3 June 2025EweitzAdd phenotype, zonulin receptors
139339view10:45, 3 June 2025EweitzAdd drugs, genes, refine interactions
139332view01:46, 3 June 2025EweitzAdd drugs
139331view23:15, 2 June 2025EweitzAdd interactions between APC and CD4 T cell
139330view22:20, 2 June 2025EweitzAdd more interactions, tissue labels
139329view11:32, 2 June 2025EweitzAdd catalysis, economize layout
139327view03:17, 2 June 2025EweitzAdd interactions, label microanatomy
139326view02:44, 2 June 2025EweitzAdd genes
139325view01:53, 2 June 2025EweitzAdd blood vessel, color tissues
139324view01:28, 2 June 2025EweitzAdd more cell types
139323view01:17, 2 June 2025EweitzColor, refine size in IECs
139322view01:12, 2 June 2025EweitzAdd villi, mucus layer, CD8 T cell
139319view20:17, 31 May 2025EweitzNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
AGYMetabolite
CALY-002Metabolite
CD4GeneProduct
DHODHGeneProduct
Deaminated

gluten

peptide		Metabolite
EGFRGeneProduct
GSK3915393Metabolite
GZMBGeneProduct
GlutenMetabolite
Gluten peptideMetabolite
HLA-DQ2GeneProduct
HLA-DQ8GeneProduct
IFNGGeneProduct
IL15GeneProduct
IL2GeneProduct
IL21GeneProduct
ITGA4GeneProduct
ITGB7GeneProduct
Inflammation
KAN-101Metabolite
LarazotideMetabolite
LatiglutenaseMetabolite
Loss of tolerance
PAR2GeneProduct
PRV-015Metabolite
PTG-100Metabolite
Pyrimidine synthesisPathway
TAK-062Metabolite
TAK-101Metabolite
TG2GeneProduct
TNFAGeneProduct
TRAGeneProduct
TRBGeneProduct
TeriflunomideMetabolite
Tolerase GMetabolite
ZED1227Metabolite

Annotated Interactions

No annotated interactions

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