Ebstein-Barr virus LMP1 signaling (Gallus gallus)

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2, 3PPPS32-PUPS36-PPS36-PTES1TES2UUS32-PNFKB2_CHICKp65NFKB1_CHICKNFKB2_CHICKIRAK1TRADDTRAF6SFC complexIKKA_CHICKI-Kappa-BMAP3K7NFKB1_CHICKp65NFKB1_CHICKIKBKBp65MAP3K3IFNBHSP90TRAF1NP_989481.1MAPK8RCJMB04_19h23p65MAP3K7I-Kappa-Bp65IL8TNFNFKB1_CHICKLMP1NP_989769.1NP_001026098.1IKK-gammap65CCL4_CHICK1, 4


Description

based on science-slides...

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP262(r29609) with a 58% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Battaglia F, Delfino S, Merello E, Puppo M, Piva R, Varesio L, Bosco MC; ''Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB.''; J Leukoc Biol, 2008 PubMed Europe PMC Scholia
  2. Song YJ, Jen KY, Soni V, Kieff E, Cahir-McFarland E; ''IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation.''; Proc Natl Acad Sci U S A, 2006 PubMed Europe PMC Scholia
  3. Uemura N, Kajino T, Sanjo H, Sato S, Akira S, Matsumoto K, Ninomiya-Tsuji J; ''TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.''; J Biol Chem, 2006 PubMed Europe PMC Scholia
  4. Lee JS, Lee JY, Son JW, Oh JH, Shin DM, Yuk JM, Song CH, Paik TH, Jo EK; ''Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis.''; Scand J Immunol, 2008 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118087view10:46, 24 May 2021EweitzModified title
109453view10:25, 18 March 2020L DupuisConverted interaction lines to graphical lines where applicable
87918view12:59, 25 July 2016SusanOntology Term : 'signaling pathway' added !
68855view17:20, 8 July 2013MaintBotUpdated to 2013 gpml schema
58780view22:16, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
40993view22:55, 1 March 2011MaintBotRemoved redundant pathway information and comments
33915view18:05, 9 December 2009MaintBotAutomatic update of empty xrefs
33443view14:58, 30 November 2009MaintBotRemoved group label
30327view20:45, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CCL4_CHICKGeneProductENSGALG00000000951 (Ensembl)
HSP90GeneProduct
I-Kappa-BGeneProduct
IFNBGeneProductENSGALG00000015062 (Ensembl)
IKBKBGeneProductENSGALG00000003740 (Ensembl)
IKK-gammaGeneProduct
IKKA_CHICKGeneProductENSGALG00000003289 (Ensembl)
IL8GeneProduct396495 (Entrez Gene)
IRAK1GeneProduct
LMP1GeneProduct
MAP3K3GeneProductENSGALG00000000525 (Ensembl)
MAP3K7GeneProductENSGALG00000015596 (Ensembl)
MAPK8GeneProductENSGALG00000006109 (Ensembl)
NFKB1_CHICKGeneProductENSGALG00000012304 (Ensembl)
NFKB2_CHICKGeneProductENSGALG00000005653 (Ensembl)
NP_001026098.1GeneProductENSGALG00000000685 (Ensembl)
NP_989481.1GeneProductENSGALG00000001501 (Ensembl)
NP_989769.1GeneProductENSGALG00000003003 (Ensembl)
RCJMB04_19h23GeneProduct423669 (Entrez Gene)
SFC complexGeneProduct
TNFGeneProduct
TRADDGeneProductENSGALG00000003195 (Ensembl)
TRAF1GeneProductENSGALG00000001583 (Ensembl)
TRAF6GeneProductENSGALG00000007932 (Ensembl)
p65GeneProduct

Annotated Interactions

No annotated interactions
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