Triacylglyceride synthesis (Gallus gallus)

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Fatty Acid Synthesis pathwayOnly 1 of these enzymes is neededDegradationPathOnly 1 of these enzymes is neededGPAMMOGAT3Dihydroxyacetone phosphatePhosphatidic acidAGPAT1GK2GlycerolGlycerol-3-phosphateMonoacylglycerolAGPAT2AGPAT4Fatty acyl CoADGAT1PNPLA2LIPEAcyl dihydroxyacetone phosphateDGAT2Fatty acyl CoAGNPATPPAP2CPPAP2ATriacylglycerolAGPAT3PPAP2BMOGAT1AYR1AGPAT5LPLLysophosphatidic acidLIPFLIPCDiacylglycerolMOGAT2AGPSGPD1Dihydroxyacetone phosphateFatty acyl CoAGK


Description

Triacylglyceride (or triglyceride) is a major component of skin oils, animal and vegetable fats, and supports the transfer of adipose and glucose between the liver and circulatory system. Triacylglyceride is synthesized from glycerol and three fatty acids. The terminal step of synthesis is performed by Diglyceride acyltransferase (DGAT).

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP325(r21363) with a 62% conversion rate.

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Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
123954view20:07, 7 September 2022AlexanderPicoadd description
118597view15:38, 28 May 2021EweitzModified title
118596view15:38, 28 May 2021EweitzOntology Term : 'triacylglycerol biosynthetic pathway' added !
107108view14:18, 17 September 2019MaintBotChEBI identifier normalization
106116view12:02, 16 August 2019MaintBotHMDB identifier normalization
74252view14:42, 11 April 2014EgonwAdded two missing metabolite identifiers.
74173view15:11, 2 April 2014EgonwUpdated the PubChem-compound and KEGG Compound data sources.
68823view17:17, 8 July 2013MaintBotUpdated to 2013 gpml schema
40959view22:53, 1 March 2011MaintBotRemoved redundant pathway information and comments
33886view17:55, 9 December 2009MaintBotAutomatic update of empty xrefs
33462view15:03, 30 November 2009MaintBotRemoved group label
31513view21:37, 13 August 2009MaintBotFixed text labels
30351view20:53, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AGPAT1GeneProduct419941 (Entrez Gene)
AGPAT2GeneProduct772114 (Entrez Gene)
AGPAT3GeneProduct418550 (Entrez Gene)
AGPAT4GeneProduct421578 (Entrez Gene)
AGPAT5GeneProduct421898 (Entrez Gene)
AGPSGeneProduct424135 (Entrez Gene)
AYR1GeneProductYeast
Acyl dihydroxyacetone phosphateMetaboliteC03372 (KEGG Compound)
DGAT1GeneProduct
DGAT2GeneProduct421309 (Entrez Gene)
DiacylglycerolMetaboliteC00165 (KEGG Compound)
Dihydroxyacetone phosphateMetaboliteCHEBI:16108 (ChEBI)
Dihydroxyacetone phosphateMetaboliteHMDB0001473 (HMDB)
Fatty acyl CoAMetaboliteCHEBI:37554 (ChEBI)
GK2GeneProduct
GKGeneProduct418589 (Entrez Gene)
GNPATGeneProduct421548 (Entrez Gene)
GPAMGeneProduct423895 (Entrez Gene)
GPD1GeneProduct424263 (Entrez Gene)
Glycerol-3-phosphateMetaboliteC00093 (KEGG Compound)
GlycerolMetaboliteCHEBI:17754 (ChEBI)
LIPCGeneProduct427495 (Entrez Gene)
LIPEGeneProduct
LIPFGeneProduct
LPLGeneProduct396219 (Entrez Gene)
Lysophosphatidic acidMetabolite5497152 (PubChem-compound)
MOGAT1GeneProduct424811 (Entrez Gene)
MOGAT2GeneProduct426437 (Entrez Gene)
MOGAT3GeneProduct
MonoacylglycerolMetaboliteC01885 (KEGG Compound)
PNPLA2GeneProduct431066 (Entrez Gene)
PPAP2AGeneProduct427138 (Entrez Gene)
PPAP2BGeneProduct424666 (Entrez Gene)
PPAP2CGeneProduct
Phosphatidic acidMetabolite5460104 (PubChem-compound)
TriacylglycerolMetaboliteC00422 (KEGG Compound)

Annotated Interactions

No annotated interactions
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