Complement activation - classical pathway (Rattus norvegicus)
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Plasma
Membrane
Membrane
attack complex
Complex
Formation
Prevents Complement Attack
aggregated IgG,
IgM-antigen complex,
polyanions, RNA, DNA
lipopolysaccharides
antigen/antibody
complex
Proteolytic Cleavage
Cytoplasm
Ions
C1 complex
C3
MASP1
C1qb
C1s
C4A
H2O
C2
C1r
C5
C1qa
C7
C8a
Cd55
C4B
C6
C8b
C1qc
C9
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP545(r21826)
with a 82% conversion rate.
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Quality Tags
Ontology Terms
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Bibliography
No bibliography
History
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Compare
Revision
Action
Time
User
Comment
116948
view
10:05, 16 May 2021
Eweitz
Modified title
107006
view
13:46, 17 September 2019
MaintBot
HMDB identifier normalization
69440
view
19:05, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67123
view
10:09, 26 June 2013
Christine Chichester
Ontology Term : 'classical complement pathway' added !
41764
view
02:41, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34132
view
19:30, 9 December 2009
MaintBot
Automatic update of empty xrefs
33483
view
15:08, 30 November 2009
MaintBot
Removed group label
31533
view
21:45, 13 August 2009
MaintBot
Fixed text labels
30925
view
00:35, 30 July 2009
MaintBot
Converted from Homo sapiens
20849
view
11:30, 14 November 2008
MaintBot
[[Pathway:Rattus norvegicus:Complement Activation Classical]] moved to [[Pathway:WP81]]: Moved to stable identifier
7970
view
13:46, 7 January 2008
MaintBot
[[Pathway:Rat:Complement Activation Classical]] moved to [[Pathway:Rattus norvegicus:Complement Activation Classical]]: Renaming species
7609
view
16:03, 18 December 2007
MaintBot
fixed category names
7466
view
12:42, 4 November 2007
MaintBot
Added categories to GPML
19409
view
22:19, 22 May 2007
M.Ramirez
gpml file for [[Rat:Complement_Activation_Classical]]
6527
view
22:19, 22 May 2007
Nsalomonis
gpml file for [[Rat:Complement_Activation_Classical]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
C1qa
GeneProduct
298566 (Entrez Gene)
update: C1QA HUMAN
C1qb
GeneProduct
29687 (Entrez Gene)
C1qc
GeneProduct
362634 (Entrez Gene)
update C1QC HUMAN
C1r
GeneProduct
312705 (Entrez Gene)
C1s
GeneProduct
192262 (Entrez Gene)
C2
GeneProduct
24231 (Entrez Gene)
C3
GeneProduct
24232 (Entrez Gene)
C4A
GeneProduct
C4B
GeneProduct
24233 (Entrez Gene)
C5
GeneProduct
362119 (Entrez Gene)
C6
GeneProduct
24237 (Entrez Gene)
C7
GeneProduct
117517 (Entrez Gene)
C8a
GeneProduct
298288 (Entrez Gene)
C8b
GeneProduct
313421 (Entrez Gene)
C9
GeneProduct
117512 (Entrez Gene)
Cd55
GeneProduct
64036 (Entrez Gene)
H2O
Metabolite
HMDB0002111 (HMDB)
MASP1
GeneProduct
64023 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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Annotated Interactions
No annotated interactions