Small ligand GPCRs (Pan troglodytes)

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Platelet ActivatingMelatoninGi PathwayCannabinoidGq/G11 PathwayGq/G11 PathwayLysophosphatidicAcidProstanoidsEDG5PTAFRMTNR1BPTGER4LPAR1CNR1PTGFRPTGER2Mel-1CTBXA2RPTGIRMTNR1AS1PR1PTGDRPTGER1S1PR4S1PR3PTGER3CNR2


Description

G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: Wikipedia These small ligand receptors are part of the Rhodopsin-like family of GPCRs. Source: Wikipedia

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP247(r21199) with a 84% conversion rate.

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Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
117409view10:39, 21 May 2021EweitzModified title
109475view11:11, 18 March 2020L DupuisConnected line
96075view18:43, 15 February 2018KhanspersModified description
96070view18:41, 15 February 2018KhanspersModified description
87676view08:55, 25 July 2016LindarieswijkOntology Term : 'G protein mediated signaling pathway' added !
71658view19:39, 17 October 2013MaintBotAutomated update of data sources
69223view18:33, 8 July 2013MaintBotUpdated to 2013 gpml schema
62735view03:33, 2 May 2013MaintBotUpdated UniProt data source
41526view01:57, 2 March 2011MaintBotRemoved redundant pathway information and comments
33523view09:32, 1 December 2009MaintBotRemoved group label
31560view21:55, 13 August 2009MaintBotFixed text labels
30422view21:16, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
CNR1GeneProduct472066 (Entrez Gene)
CNR2GeneProduct456625 (Entrez Gene)
EDG5GeneProduct
LPAR1GeneProduct464655 (Entrez Gene)
MTNR1AGeneProduct471417 (Entrez Gene)
MTNR1BGeneProduct466747 (Entrez Gene)
Mel-1CGeneProduct
PTAFRGeneProduct469249 (Entrez Gene)
PTGDRGeneProduct452906 (Entrez Gene)
PTGER1GeneProduct747643 (Entrez Gene)
PTGER2GeneProduct467459 (Entrez Gene)
PTGER3GeneProduct456940 (Entrez Gene)
PTGER4GeneProduct450195 (Entrez Gene)
PTGFRGeneProduct456970 (Entrez Gene)
PTGIRGeneProduct
S1PR1GeneProduct457063 (Entrez Gene)
S1PR3GeneProduct464580 (Entrez Gene)
S1PR4GeneProduct455581 (Entrez Gene)
TBXA2RGeneProduct468667 (Entrez Gene)

Annotated Interactions

No annotated interactions
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