Focal adhesion: PI3K-Akt-mTOR-signaling (Homo sapiens)

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<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Focal Adhesion-PI3K-Akt-mTOR-signaling pathway" Organism="Homo sapiens"> <Comment Source="WikiPathways-description">Cell-matrix adhesions play important roles in biological processes such as cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. Focal adhesions are structures formed at the cell-extracellular matrix contact points, consisting of bundles of actin filaments anchored to trans-membrane receptors of the integrin family through a complex of multiple proteins. In addition to participating in the structural link between membrane receptors and the actin cytoskeleton, focal adhesions also contain signaling molecules, such as protein kinases and phosphatases, their substrates, and various adapter proteins. Integrin signaling is dependent on the non-receptor tyrosine kinase activities of the FAK and src proteins and the adaptor protein functions of FAK, src and Shc to initiate downstream signaling events. These signaling events results in the reorganization of the actin cytoskeleton, which is essential for changes in cell shape and motility, and gene expression. Source: [https://www.genome.jp/dbget-bin/www_bget?pathway+map04510 KEGG] Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP3932 CPTAC Assay Portal]</Comment> <Comment Source="HomologyMapper">This pathway was inferred from Mus musculus pathway "Focal Adhesion-PI3K-Akt-mTOR-signaling pathway", WP2841 revision 89989, with a 94.0% conversion rate.</Comment> <BiopaxRef>b50</BiopaxRef> <BiopaxRef>c61</BiopaxRef> <BiopaxRef>d8a</BiopaxRef> <BiopaxRef>b72</BiopaxRef> <BiopaxRef>bd6</BiopaxRef> <BiopaxRef>c9e</BiopaxRef> <BiopaxRef>a08</BiopaxRef> <BiopaxRef>bff</BiopaxRef> <BiopaxRef>c3a</BiopaxRef> <BiopaxRef>c43</BiopaxRef> <BiopaxRef>be2</BiopaxRef> <BiopaxRef>d05</BiopaxRef> <BiopaxRef>b3d</BiopaxRef> <BiopaxRef>b73</BiopaxRef> <BiopaxRef>a93</BiopaxRef> <BiopaxRef>fed</BiopaxRef> <BiopaxRef>d31</BiopaxRef> <Graphics BoardWidth="2286.0" BoardHeight="1373.6241610738255"/> <DataNode TextLabel="NOS2" GraphId="e0405" Type="GeneProduct" GroupRef="ecf10"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18126</Comment> <Graphics CenterX="1565.9999999999986" CenterY="1296.9999999999927" Width="60.0" Height="20.0" ZOrder="-6" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000007171"/> </DataNode> <DataNode TextLabel="NOS3" GraphId="b8326" Type="GeneProduct" GroupRef="ecf10"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18127</Comment> <Graphics CenterX="1565.9999999999986" CenterY="1316.9999999999927" Width="60.0" Height="20.0" ZOrder="4137" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000164867"/> </DataNode> <DataNode TextLabel="ITGA5" GraphId="c09" Type="GeneProduct" 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Homo sapiens: Original ID = L:16775</Comment> <Graphics CenterX="130.66666666666669" CenterY="339.66666666666646" Width="60.0" Height="20.0" ZOrder="32876" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000112769"/> </DataNode> <DataNode TextLabel="ITGA8" GraphId="f95" Type="GeneProduct" GroupRef="c3526"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:241226</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGA8"/> <Graphics CenterX="510.6666666666681" CenterY="246.66666666666657" Width="60.0" Height="20.0" ZOrder="32878" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000077943"/> </DataNode> <DataNode TextLabel="COL4A1" GraphId="a17" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12826</Comment> <Graphics CenterX="58.000000000000014" CenterY="300.66666666666646" Width="60.0" Height="20.0" ZOrder="32880" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000187498"/> </DataNode> <DataNode TextLabel="LAMA3" GraphId="f71" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000024421</Comment> <Graphics CenterX="130.66666666666669" CenterY="319.66666666666646" Width="60.0" Height="20.0" ZOrder="32882" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000053747"/> </DataNode> <DataNode TextLabel="LAMC1" GraphId="f2b" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:226519</Comment> <Graphics CenterX="200.33333333333331" CenterY="418.66666666666646" Width="60.0" Height="20.0" ZOrder="32884" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000135862"/> </DataNode> <DataNode TextLabel="LAMB2" GraphId="f45" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16779</Comment> <Graphics CenterX="130.66666666666669" CenterY="399.66666666666646" Width="60.0" Height="20.0" ZOrder="32886" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000172037"/> </DataNode> <DataNode TextLabel="THBS4" GraphId="a71" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21828</Comment> <Graphics CenterX="200.33333333333331" CenterY="318.66666666666646" Width="60.0" Height="20.0" ZOrder="32888" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000113296"/> </DataNode> <DataNode TextLabel="COL2A1" GraphId="bda" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12824</Comment> <Graphics CenterX="58.000000000000014" CenterY="260.66666666666646" 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Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000051382"/> </DataNode> <DataNode TextLabel="THBS3" GraphId="bb9" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21827</Comment> <Graphics CenterX="200.33333333333331" CenterY="298.66666666666646" Width="60.0" Height="20.0" ZOrder="32896" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000169231"/> </DataNode> <DataNode TextLabel="ITGA10" GraphId="c57" Type="GeneProduct" GroupRef="c3526"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000090210</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGA10"/> <Graphics CenterX="510.6666666666681" CenterY="286.6666666666666" Width="60.0" Height="20.0" ZOrder="32898" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000143127"/> </DataNode> <DataNode TextLabel="ITGAV" GraphId="d34" Type="GeneProduct" GroupRef="c3526"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = M:MGI:96608</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Itgav"/> <Graphics CenterX="575.6666666666677" CenterY="307.33333333333303" Width="60.0" Height="20.0" ZOrder="32900" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000138448"/> </DataNode> <DataNode TextLabel="PRLR" GraphId="a83" Type="GeneProduct" GroupRef="d9c68"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19116</Comment> <Graphics CenterX="422.66666666666583" CenterY="1059.15673289183" Width="60.0" Height="20.0" ZOrder="32902" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000113494"/> </DataNode> <DataNode TextLabel="IL7R" GraphId="dd7" Type="GeneProduct" GroupRef="d9c68"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16197</Comment> <Graphics CenterX="494.66666666666515" CenterY="1059.15673289183" Width="60.0" Height="20.0" ZOrder="32904" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000168685"/> </DataNode> <DataNode TextLabel="ITGA6" GraphId="ccb" Type="GeneProduct" GroupRef="c3526"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16403</Comment> <Graphics CenterX="443.6666666666679" CenterY="325.66666666666663" Width="60.0" Height="20.0" ZOrder="32906" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000091409"/> </DataNode> <DataNode TextLabel="LAMA5" GraphId="c2b" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16776</Comment> <Graphics CenterX="130.66666666666669" CenterY="359.66666666666646" Width="60.0" Height="20.0" ZOrder="32908" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000130702"/> </DataNode> <DataNode TextLabel="IL6R" GraphId="f1e" Type="GeneProduct" GroupRef="d9c68"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16194</Comment> <Graphics CenterX="494.66666666666515" CenterY="1039.1567328918309" Width="60.0" Height="20.0" ZOrder="32910" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000160712"/> </DataNode> <DataNode TextLabel="ITGB1" GraphId="f94" Type="GeneProduct" GroupRef="b6026"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16412</Comment> <Graphics CenterX="443.33333333333303" CenterY="361.9999999999997" Width="60.0" Height="20.0" ZOrder="32912" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000150093"/> </DataNode> <DataNode TextLabel="IBSP" GraphId="b75" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15891</Comment> <Graphics CenterX="130.66666666666669" CenterY="259.66666666666646" Width="60.0" Height="20.0" ZOrder="32914" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000029559"/> </DataNode> <DataNode TextLabel="Insulin" GraphId="dba46" Type="Metabolite"> <Graphics CenterX="226.45290581162317" CenterY="862.7254509018035" Width="90.0" Height="25.0" ZOrder="32916" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:5931"/> </DataNode> <DataNode TextLabel="Itgam" GraphId="b4d" Type="GeneProduct" GroupRef="c3526"> <Comment Source="HomologyMapper">Multiple homologues found: En:ENSG00000169896;En:ENSG00000169896;</Comment> <Graphics CenterX="575.6666666666677" CenterY="287.33333333333303" Width="60.0" Height="20.0" ZOrder="32918" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="COL6A2" GraphId="faf" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12834</Comment> <Graphics CenterX="58.000000000000014" CenterY="400.66666666666646" Width="60.0" Height="20.0" ZOrder="32920" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000142173"/> </DataNode> <DataNode TextLabel="VWF" GraphId="d61" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22371</Comment> <Graphics CenterX="200.33333333333331" CenterY="398.66666666666646" Width="60.0" Height="20.0" ZOrder="32922" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000110799"/> </DataNode> <DataNode TextLabel="TNXB" GraphId="c91" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:81877</Comment> <Graphics CenterX="279.66666666666674" CenterY="279.66666666666646" Width="60.0" Height="20.0" ZOrder="32924" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000168477"/> </DataNode> <DataNode TextLabel="ITGB5" GraphId="fb0" Type="GeneProduct" GroupRef="b6026"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16419</Comment> <Graphics CenterX="510.33333333333303" CenterY="380.99999999999994" Width="60.0" Height="20.0" ZOrder="32926" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000082781"/> </DataNode> <DataNode TextLabel="TNN" GraphId="b02" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:329278</Comment> <Graphics CenterX="279.66666666666674" CenterY="239.66666666666677" Width="60.0" Height="20.0" ZOrder="32928" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000120332"/> </DataNode> <DataNode TextLabel="SPP1" GraphId="e45" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20750</Comment> <Graphics CenterX="200.33333333333331" CenterY="238.66666666666677" Width="60.0" Height="20.0" ZOrder="32930" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000118785"/> </DataNode> <DataNode TextLabel="PTEN" GraphId="f7f" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19211</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pten"/> <Graphics CenterX="1080.666666666666" CenterY="803.9999999999961" Width="60.0" Height="20.0" ZOrder="32932" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000171862"/> </DataNode> <DataNode TextLabel="LAMA2" GraphId="bcb" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16773</Comment> <Graphics CenterX="130.66666666666669" CenterY="299.66666666666646" Width="60.0" Height="20.0" ZOrder="32934" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000196569"/> </DataNode> <DataNode TextLabel="CSF3R" GraphId="daf" Type="GeneProduct" GroupRef="d9c68"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986</Comment> <Graphics CenterX="422.66666666666583" CenterY="939.1567328918311" Width="60.0" Height="20.0" ZOrder="32936" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000119535"/> </DataNode> <DataNode TextLabel="IL2RA" GraphId="f78" Type="GeneProduct" GroupRef="d9c68"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16184</Comment> <Graphics CenterX="494.66666666666515" CenterY="939.1567328918306" Width="60.0" Height="20.0" ZOrder="32938" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000134460"/> </DataNode> <DataNode TextLabel="EPOR" GraphId="b3b" Type="GeneProduct" GroupRef="d9c68"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13857</Comment> <Graphics CenterX="422.66666666666583" CenterY="959.1567328918311" Width="60.0" Height="20.0" ZOrder="32940" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000187266"/> </DataNode> <DataNode TextLabel="COL3A1" GraphId="d63" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12825</Comment> <Graphics CenterX="58.000000000000014" CenterY="280.66666666666646" Width="60.0" Height="20.0" ZOrder="32942" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000168542"/> </DataNode> <DataNode TextLabel="ITGAL" GraphId="fbf" Type="GeneProduct" GroupRef="c3526"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16408</Comment> <Graphics CenterX="575.6666666666677" CenterY="267.33333333333303" Width="60.0" Height="20.0" ZOrder="32944" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000005844"/> </DataNode> <DataNode TextLabel="IL4R" GraphId="d93" Type="GeneProduct" GroupRef="d9c68"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16190</Comment> <Graphics CenterX="494.66666666666515" CenterY="1019.1567328918305" Width="60.0" Height="20.0" ZOrder="32946" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000077238"/> </DataNode> <DataNode TextLabel="LAMA1" GraphId="d5a" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16772</Comment> <Graphics CenterX="130.66666666666669" CenterY="279.66666666666646" Width="60.0" Height="20.0" ZOrder="32948" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000101680"/> </DataNode> <DataNode TextLabel="SOS1" GraphId="a8c" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20662</Comment> <Graphics CenterX="701.9999999999982" CenterY="657.6666666666662" Width="60.0" Height="20.0" ZOrder="32950" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000115904"/> </DataNode> <DataNode TextLabel="ITGB3" GraphId="c1f" Type="GeneProduct" GroupRef="b6026"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16416</Comment> <Graphics CenterX="443.33333333333303" CenterY="401.99999999999983" Width="60.0" Height="20.0" ZOrder="32952" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000259207"/> </DataNode> <DataNode TextLabel="TSC2" GraphId="a32" Type="GeneProduct" GroupRef="c1fa1"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22084</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Actg1"/> <Graphics CenterX="1425.3333333333333" CenterY="474.0000000000013" Width="60.0" Height="20.0" ZOrder="32954" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000103197"/> </DataNode> <DataNode TextLabel="PIK3CD" GraphId="f1c" Type="GeneProduct" GroupRef="b6d19"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18707</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pik3cd"/> <Graphics CenterX="877.6666666666686" CenterY="898.9999999999984" Width="60.0" Height="20.0" ZOrder="32956" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000171608"/> </DataNode> <DataNode TextLabel="ITGB8" GraphId="c0e" Type="GeneProduct" GroupRef="b6026"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320910</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGB8"/> <Graphics CenterX="576.3333333333333" CenterY="380.9999999999999" 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GroupRef="dd71d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:23797</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Akt3"/> <Graphics CenterX="1213.3333333333326" CenterY="912.666666666664" Width="60.0" Height="20.0" ZOrder="32964" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000117020"/> </DataNode> <DataNode TextLabel="COL1A1" GraphId="cbe" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12842</Comment> <Graphics CenterX="58.000000000000014" CenterY="420.66666666666646" Width="60.0" Height="20.0" ZOrder="32966" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000108821"/> </DataNode> <DataNode TextLabel="COL11A1" GraphId="e8c" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12814</Comment> <Graphics CenterX="58.000000000000014" CenterY="220.66666666666677" Width="60.0" Height="20.0" ZOrder="32968" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000060718"/> </DataNode> <DataNode TextLabel="PIK3R4" GraphId="f8a" Type="GeneProduct" GroupRef="b6d19"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75669</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pik3r4"/> <Graphics CenterX="957.6666666666686" CenterY="898.333333333331" Width="60.0" Height="20.0" ZOrder="32970" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000196455"/> </DataNode> <DataNode TextLabel="COL5A3" GraphId="a60" Type="GeneProduct" GroupRef="d596d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867</Comment> <Graphics CenterX="279.66666666666674" CenterY="259.66666666666646" Width="60.0" Height="20.0" ZOrder="32972" FontSize="10" 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<Graphics CenterX="1213.3333333333326" CenterY="892.666666666664" Width="60.0" Height="20.0" ZOrder="32982" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000105221"/> </DataNode> <DataNode TextLabel="ITGA4" GraphId="e91" Type="GeneProduct" GroupRef="c3526"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16401</Comment> <Graphics CenterX="443.6666666666679" CenterY="285.6666666666666" Width="60.0" Height="20.0" ZOrder="32984" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000115232"/> </DataNode> <DataNode TextLabel="GHR" GraphId="f1d" Type="GeneProduct" GroupRef="d9c68"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14600</Comment> <Graphics CenterX="422.66666666666583" CenterY="979.1567328918311" Width="60.0" Height="20.0" ZOrder="32986" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000112964"/> </DataNode> <DataNode TextLabel="ITGA11" GraphId="ab9" Type="GeneProduct" GroupRef="c3526"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:319480</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGA11"/> <Graphics CenterX="510.6666666666681" CenterY="306.6666666666666" Width="60.0" Height="20.0" ZOrder="32988" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000137809"/> </DataNode> <DataNode TextLabel="PIK3R5" GraphId="cc476" Type="GeneProduct" GroupRef="ea9b1"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320207</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pik3r5"/> <Graphics CenterX="923.5408388520987" CenterY="1204.0375275938127" Width="60.0" Height="20.0" ZOrder="32990" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000141506"/> </DataNode> <DataNode TextLabel="EFNA1" GraphId="ad1ae" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13636</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfa"/> <Graphics CenterX="42.6666666666666" CenterY="598.6666666666666" Width="60.0" Height="20.0" ZOrder="32992" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000169242"/> </DataNode> <DataNode TextLabel="FGF1" GraphId="b6ea4" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14164</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="184.6666666666668" CenterY="519.9999999999993" Width="60.0" Height="20.0" ZOrder="32994" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000113578"/> </DataNode> <DataNode TextLabel="FGF11" GraphId="f1fe9" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14166</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="VEGFA"/> <Graphics CenterX="114.0000000000001" CenterY="559.9999999999993" Width="60.0" Height="20.0" ZOrder="32996" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000161958"/> </DataNode> <DataNode TextLabel="FGF10" GraphId="acd4b" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14165</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pgf"/> <Graphics CenterX="114.0000000000001" CenterY="539.9999999999994" Width="60.0" Height="20.0" ZOrder="32998" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000070193"/> </DataNode> <DataNode TextLabel="EFNA2" GraphId="dd7b3" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13637</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="42.6666666666666" CenterY="618.6666666666667" Width="60.0" Height="20.0" ZOrder="33000" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000099617"/> </DataNode> <DataNode TextLabel="EGF" GraphId="bdc01" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13645</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfc"/> <Graphics CenterX="114.0000000000001" CenterY="520.4217804667244" Width="60.0" Height="20.0" ZOrder="33002" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000138798"/> </DataNode> <DataNode TextLabel="FGF12" GraphId="d6e80" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14167</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Vegfb"/> <Graphics CenterX="114.0000000000001" CenterY="579.9999999999994" Width="60.0" Height="20.0" ZOrder="33004" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000114279"/> </DataNode> <DataNode TextLabel="CSF1" GraphId="c2f51" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12977</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Igf1"/> <Graphics CenterX="42.6666666666666" CenterY="578.6666666666669" Width="60.0" Height="20.0" ZOrder="33006" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000184371"/> </DataNode> <DataNode TextLabel="ANGPT4" GraphId="dd423" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11602</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hgf"/> <Graphics CenterX="42.6666666666666" CenterY="558.6666666666667" Width="60.0" Height="20.0" ZOrder="33008" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000101280"/> </DataNode> <DataNode TextLabel="ANGPT2" GraphId="cd1de" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11601</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Figf"/> <Graphics CenterX="42.6666666666666" CenterY="538.6666666666666" Width="60.0" Height="20.0" ZOrder="33010" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000091879"/> </DataNode> <DataNode TextLabel="ANGPT1" GraphId="f049b" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11600</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Egf"/> <Graphics CenterX="42.6666666666666" CenterY="518.6666666666667" Width="60.0" Height="20.0" ZOrder="33012" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000154188"/> </DataNode> <DataNode TextLabel="VEGFA" GraphId="e4767" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22339</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Vegfc"/> <Graphics CenterX="328.00000000000017" CenterY="579.3333333333375" Width="60.0" Height="20.0" ZOrder="33014" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000112715"/> </DataNode> <DataNode TextLabel="EFNA3" GraphId="d44cf" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13638</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="42.6666666666666" CenterY="638.6666666666667" Width="60.0" Height="20.0" ZOrder="33016" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000143590"/> </DataNode> <DataNode TextLabel="EFNA4" GraphId="cb5d4" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13639</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="42.6666666666666" CenterY="658.6666666666667" Width="60.0" Height="20.0" ZOrder="33018" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000243364"/> </DataNode> <DataNode TextLabel="EFNA5" GraphId="bc53c" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13640</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="42.6666666666666" CenterY="678.6666666666666" Width="60.0" Height="20.0" ZOrder="33020" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000184349"/> </DataNode> <DataNode TextLabel="FGF14" GraphId="f4ea9" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14169</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="VEGFA"/> <Graphics CenterX="114.0000000000001" CenterY="619.9999999999995" Width="60.0" Height="20.0" ZOrder="33022" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000102466"/> </DataNode> <DataNode TextLabel="FGF13" GraphId="e49f5" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14168</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pgf"/> <Graphics CenterX="114.0000000000001" CenterY="599.9999999999994" Width="60.0" Height="20.0" ZOrder="33024" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000129682"/> </DataNode> <DataNode TextLabel="FGF19" GraphId="e466c" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14170</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Vegfb"/> <Graphics CenterX="114.0000000000001" CenterY="639.9999999999995" Width="60.0" Height="20.0" ZOrder="33026" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000162344"/> </DataNode> <DataNode TextLabel="FGF17" GraphId="ddb18" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14171</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="VEGFA"/> <Graphics CenterX="114.0000000000001" CenterY="659.9999999999995" Width="60.0" Height="20.0" ZOrder="33028" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000158815"/> </DataNode> <DataNode TextLabel="FGF18" GraphId="ff5ba" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14172</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Vegfb"/> <Graphics CenterX="114.0000000000001" CenterY="679.9999999999994" Width="60.0" Height="20.0" ZOrder="33030" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000156427"/> </DataNode> <DataNode TextLabel="FGF2" GraphId="d16c1" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14173</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="184.6666666666668" CenterY="539.9999999999994" Width="60.0" Height="20.0" ZOrder="33032" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000138685"/> </DataNode> <DataNode TextLabel="FGF3" GraphId="bcee7" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14174</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="184.6666666666668" CenterY="559.9999999999993" Width="60.0" Height="20.0" ZOrder="33034" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000186895"/> </DataNode> <DataNode TextLabel="FGF4" GraphId="cb80c" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14175</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="184.6666666666668" CenterY="579.9999999999994" Width="60.0" Height="20.0" ZOrder="33036" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000075388"/> </DataNode> <DataNode TextLabel="FGF6" GraphId="d0ca1" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14177</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="184.6666666666668" CenterY="599.9999999999994" Width="60.0" Height="20.0" ZOrder="33038" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000111241"/> </DataNode> <DataNode TextLabel="FGF7" GraphId="a0277" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14178</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="184.6666666666668" CenterY="619.9999999999995" Width="60.0" Height="20.0" ZOrder="33040" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000140285"/> </DataNode> <DataNode TextLabel="FGF8" GraphId="d5bb9" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14179</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="184.6666666666668" CenterY="639.9999999999995" Width="60.0" Height="20.0" ZOrder="33042" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000107831"/> </DataNode> <DataNode TextLabel="FGF9" GraphId="f515d" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14180</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="184.6666666666668" CenterY="659.9999999999995" Width="60.0" Height="20.0" ZOrder="33044" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000102678"/> </DataNode> <DataNode TextLabel="VEGFD" GraphId="cad42" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14205</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="255.3333333333331" CenterY="516.0000000000036" Width="60.0" Height="20.0" ZOrder="33046" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000165197"/> </DataNode> <DataNode TextLabel="HGF" GraphId="d709c" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15234</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="255.33333333333286" CenterY="536.000000000004" Width="60.000000000000036" Height="20.0" ZOrder="33048" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000019991"/> </DataNode> <DataNode TextLabel="IGF1" GraphId="da9f8" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16000</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="255.33333333333292" CenterY="556.0000000000039" Width="60.000000000000036" Height="20.0" ZOrder="33050" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000017427"/> </DataNode> <DataNode TextLabel="INS" GraphId="e7137" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16333</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="255.33333333333292" CenterY="576.000000000004" Width="60.000000000000036" Height="20.0" ZOrder="33052" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000254647"/> </DataNode> <DataNode TextLabel="INS" GraphId="aa05c" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16334</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="255.33333333333297" CenterY="596.000000000004" Width="60.000000000000036" Height="20.0" ZOrder="33054" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000254647"/> </DataNode> <DataNode TextLabel="KITLG" GraphId="b2a23" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17311</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="328.00000000000017" CenterY="539.3333333333375" Width="60.0" Height="20.0" ZOrder="33056" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000049130"/> </DataNode> <DataNode TextLabel="Kik1b4" GraphId="a806f" Type="GeneProduct" GroupRef="c4502"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="255.33333333333297" CenterY="616.0000000000041" Width="60.000000000000036" Height="20.0" ZOrder="33058" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="Kik1b4" GraphId="f966e" Type="GeneProduct" GroupRef="c4502"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="328.00000000000017" CenterY="519.333333333336" Width="60.0" Height="20.0" ZOrder="33060" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="VEGFC" GraphId="c2182" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22341</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="328.00000000000017" CenterY="619.3333333333376" Width="60.0" Height="20.0" ZOrder="33062" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000150630"/> </DataNode> <DataNode TextLabel="VEGFB" GraphId="a98c3" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22340</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Vegfc"/> <Graphics CenterX="328.00000000000017" CenterY="599.3333333333375" Width="60.0" Height="20.0" ZOrder="33064" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000173511"/> </DataNode> <DataNode TextLabel="PDGFB" GraphId="af251" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18591</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="255.33333333333297" CenterY="656.0000000000041" Width="60.000000000000036" Height="20.0" ZOrder="33066" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000100311"/> </DataNode> <DataNode TextLabel="PGF" GraphId="def2d" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18654</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="185.99999999999906" CenterY="681.3333333333378" Width="60.0" Height="20.0" ZOrder="33068" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000119630"/> </DataNode> <DataNode TextLabel="PDGFA" GraphId="e9140" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18590</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="255.33333333333292" CenterY="636.0000000000041" Width="60.000000000000036" Height="20.0" ZOrder="33070" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000197461"/> </DataNode> <DataNode TextLabel="NGF" GraphId="a93db" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18049</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="328.00000000000017" CenterY="559.3333333333374" Width="60.0" Height="20.0" ZOrder="33072" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000134259"/> </DataNode> <DataNode TextLabel="PDGFC" GraphId="bc0fe" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:54635</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="255.33333333333297" CenterY="676.000000000004" Width="60.000000000000036" Height="20.0" ZOrder="33074" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000145431"/> </DataNode> <DataNode TextLabel="FGF21" GraphId="afc3f" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56636</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="328.00000000000017" CenterY="679.3333333333375" Width="60.0" Height="20.0" ZOrder="33076" FontWeight="Bold" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000105550"/> </DataNode> <DataNode TextLabel="Fgf23" GraphId="b15d6" Type="GeneProduct" GroupRef="c4502"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="328.00000000000017" CenterY="719.3333333333377" Width="60.0" Height="20.0" ZOrder="33078" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="FGF22" GraphId="e4119" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67112</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="328.00000000000017" CenterY="699.3333333333375" Width="60.0" Height="20.0" ZOrder="33080" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000070388"/> </DataNode> <DataNode TextLabel="PDGFD" GraphId="c4b1a" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:71785</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="255.33333333333297" CenterY="696.0000000000041" Width="60.000000000000036" Height="20.0" ZOrder="33082" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000170962"/> </DataNode> <DataNode TextLabel="FGF20" GraphId="fa4d8" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:80857</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="328.00000000000017" CenterY="659.3333333333376" Width="60.0" Height="20.0" ZOrder="33084" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000078579"/> </DataNode> <DataNode TextLabel="FGF16" GraphId="b854a" Type="GeneProduct" GroupRef="c4502"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:80903</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfd"/> <Graphics CenterX="328.00000000000017" CenterY="639.3333333333376" Width="60.0" Height="20.0" ZOrder="33086" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000196468"/> </DataNode> <DataNode TextLabel="FGFR2" GraphId="ff781" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14183</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfa"/> <Graphics CenterX="427.99999999999983" CenterY="616.666666666667" Width="60.0" Height="20.0" ZOrder="33090" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000066468"/> </DataNode> <DataNode TextLabel="KDR" GraphId="ac132" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16542</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="VEGFA"/> <Graphics CenterX="498.0000000000003" CenterY="578.0000000000002" Width="60.0" Height="20.0" ZOrder="33092" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000128052"/> </DataNode> <DataNode TextLabel="INSR" GraphId="efaff" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16337</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pgf"/> <Graphics CenterX="498.0000000000003" CenterY="558.0000000000002" Width="60.0" Height="20.0" ZOrder="33094" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000171105"/> </DataNode> <DataNode TextLabel="FGFR3" GraphId="ff7d5" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14184</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="427.99999999999983" CenterY="636.6666666666669" Width="60.0" Height="20.0" ZOrder="33096" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000068078"/> </DataNode> <DataNode TextLabel="IGF1R" GraphId="d58f8" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16001</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfc"/> <Graphics CenterX="498.0000000000003" CenterY="538.0000000000006" Width="60.0" Height="20.0" ZOrder="33098" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000140443"/> </DataNode> <DataNode TextLabel="KIT" GraphId="c838d" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16590</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Vegfb"/> <Graphics CenterX="498.0000000000003" CenterY="598.0000000000001" Width="60.0" Height="20.0" ZOrder="33100" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000157404"/> </DataNode> <DataNode TextLabel="FGFR1" GraphId="b239d" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14182</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Igf1"/> <Graphics CenterX="427.99999999999983" CenterY="596.6666666666673" Width="60.0" Height="20.0" ZOrder="33102" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000077782"/> </DataNode> <DataNode TextLabel="EPHA2" GraphId="ac62e" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13836</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Hgf"/> <Graphics CenterX="427.99999999999983" CenterY="576.6666666666672" Width="60.0" Height="20.0" ZOrder="33104" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000142627"/> </DataNode> <DataNode TextLabel="EGFR" GraphId="c8aa7" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13649</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Figf"/> <Graphics CenterX="427.99999999999983" CenterY="556.6666666666672" Width="60.0" Height="20.0" ZOrder="33106" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000146648"/> </DataNode> <DataNode TextLabel="CSF1R" GraphId="ead60" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12978</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Egf"/> <Graphics CenterX="427.99999999999983" CenterY="536.6666666666675" Width="60.0" Height="20.0" ZOrder="33108" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000182578"/> </DataNode> <DataNode TextLabel="FGFR4" GraphId="c0c98" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14186</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="427.99999999999983" CenterY="656.6666666666669" Width="60.0" Height="20.0" ZOrder="33110" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000160867"/> </DataNode> <DataNode TextLabel="FLT1" GraphId="dfe99" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14254</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="427.99999999999983" CenterY="676.6666666666673" Width="60.0" Height="20.0" ZOrder="33112" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000102755"/> </DataNode> <DataNode TextLabel="FLT4" GraphId="c7918" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14257</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="427.99999999999983" CenterY="696.6666666666674" Width="60.0" Height="20.0" ZOrder="33114" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000037280"/> </DataNode> <DataNode TextLabel="NGFR" GraphId="b08a6" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18053</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="VEGFA"/> <Graphics CenterX="498.0000000000003" CenterY="637.9999999999999" Width="60.0" Height="20.0" ZOrder="33116" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000064300"/> </DataNode> <DataNode TextLabel="MET" GraphId="ec150" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17295</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pgf"/> <Graphics CenterX="498.0000000000003" CenterY="618.0" Width="60.0" Height="20.0" ZOrder="33118" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000105976"/> </DataNode> <DataNode TextLabel="PDGFRA" GraphId="d1b04" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18595</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Vegfb"/> <Graphics CenterX="498.0000000000003" CenterY="657.9999999999998" Width="60.0" Height="20.0" ZOrder="33120" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000134853"/> </DataNode> <DataNode TextLabel="PDGFRB" GraphId="acb73" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18596</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="VEGFA"/> <Graphics CenterX="498.0000000000003" CenterY="678.0000000000003" Width="60.0" Height="20.0" ZOrder="33122" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000113721"/> </DataNode> <DataNode TextLabel="TEK" GraphId="ede2f" Type="GeneProduct" GroupRef="bd2e6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21687</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Vegfb"/> <Graphics CenterX="498.0000000000003" CenterY="698.0000000000005" Width="60.0" Height="20.0" ZOrder="33124" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000120156"/> </DataNode> <DataNode TextLabel="AKT1S1" GraphId="c2c18" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67605</Comment> <Graphics CenterX="1551.3333333333267" CenterY="630.9999999999969" Width="60.0" Height="20.0" ZOrder="33128" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000204673"/> </DataNode> <DataNode TextLabel="IFNA7" GraphId="d4d34" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15967</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="71.99999999999898" CenterY="988.0000000000014" Width="60.0" Height="20.0" ZOrder="33130" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000214042"/> </DataNode> <DataNode TextLabel="IFNA7" GraphId="d1cc7" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15968</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="71.99999999999898" CenterY="1008.0000000000009" Width="60.0" Height="20.0" ZOrder="33132" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000214042"/> </DataNode> <DataNode TextLabel="IFNA7" GraphId="e74ad" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15969</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="71.99999999999909" CenterY="1028.0000000000005" Width="60.0" Height="20.0" ZOrder="33134" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000214042"/> </DataNode> <DataNode TextLabel="IFNA7" GraphId="eef92" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15970</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="71.99999999999898" CenterY="1047.9999999999998" Width="60.0" Height="20.0" ZOrder="33136" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000214042"/> </DataNode> <DataNode TextLabel="IFNA7" GraphId="f196b" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15972</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="71.99999999999898" CenterY="1068.000000000001" Width="60.0" Height="20.0" ZOrder="33138" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000214042"/> </DataNode> <DataNode TextLabel="IFNA7" GraphId="aa284" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15974</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="217.33333333333258" CenterY="987.9999999999995" Width="60.0" Height="20.0" ZOrder="33140" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000214042"/> </DataNode> <DataNode TextLabel="IFNB1" GraphId="df635" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15977</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="217.33333333333246" CenterY="1007.9999999999991" Width="60.0" Height="20.0" ZOrder="33142" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000171855"/> </DataNode> <DataNode TextLabel="IL2" GraphId="f4382" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="143.33333333333144" CenterY="1008.6666666666679" Width="60.0" Height="20.0" ZOrder="33144" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000109471"/> </DataNode> <DataNode TextLabel="OSM" GraphId="c672f" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18413</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="143.33333333333144" CenterY="928.6666666666667" Width="60.0" Height="20.0" ZOrder="33146" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000099985"/> </DataNode> <DataNode TextLabel="PRL" GraphId="f8a47" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19109</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="143.33333333333144" CenterY="948.6666666666674" Width="60.0" Height="20.0" ZOrder="33148" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000172179"/> </DataNode> <DataNode TextLabel="IFNA7" GraphId="e4a76" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:230396</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="143.33333333333144" CenterY="968.6666666666681" Width="60.0" Height="20.0" ZOrder="33150" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000214042"/> </DataNode> <DataNode TextLabel="Gm12597" GraphId="bd005" Type="GeneProduct" GroupRef="ff272"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="143.33333333333144" CenterY="988.6666666666683" Width="60.0" Height="20.0" ZOrder="33152" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="Ifna12" GraphId="dbc67" Type="GeneProduct" GroupRef="ff272"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="143.33333333333144" CenterY="1028.6666666666679" Width="60.0" Height="20.0" ZOrder="33154" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="IFNA7" GraphId="ead01" Type="GeneProduct" GroupRef="ff272"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:404549</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="143.33333333333144" CenterY="1048.6666666666665" Width="60.0" Height="20.0" ZOrder="33156" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000214042"/> </DataNode> <DataNode TextLabel="CHRM1" GraphId="cfff9" Type="GeneProduct" GroupRef="a2ef6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12669</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Igf1"/> <Graphics CenterX="347.9999999999998" CenterY="1167.999999999998" Width="60.0" Height="20.0" ZOrder="33160" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000168539"/> </DataNode> <DataNode TextLabel="LPAR1" GraphId="f17d2" Type="GeneProduct" GroupRef="a2ef6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14745</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="418.6666666666666" CenterY="1166.6666666666656" Width="60.0" Height="20.0" ZOrder="33162" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000198121"/> </DataNode> <DataNode TextLabel="F2R" GraphId="b912f" Type="GeneProduct" GroupRef="a2ef6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14062</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfa"/> <Graphics CenterX="347.9999999999998" CenterY="1207.999999999998" Width="60.0" Height="20.0" ZOrder="33164" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000181104"/> </DataNode> <DataNode TextLabel="CHRM2" GraphId="d75cd" Type="GeneProduct" GroupRef="a2ef6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:243764</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="347.9999999999998" CenterY="1187.999999999998" Width="60.0" Height="20.0" ZOrder="33166" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000181072"/> </DataNode> <DataNode TextLabel="LPAR5" GraphId="d4d14" Type="GeneProduct" GroupRef="a2ef6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:381810</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="418.6666666666666" CenterY="1206.6666666666656" Width="60.0" Height="20.0" ZOrder="33168" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000184574"/> </DataNode> <DataNode TextLabel="LPAR2" GraphId="cbfe8" Type="GeneProduct" GroupRef="a2ef6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53978</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="418.6666666666666" CenterY="1226.6666666666656" Width="60.0" Height="20.0" ZOrder="33170" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000064547"/> </DataNode> <DataNode TextLabel="LPAR3" GraphId="b64c0" Type="GeneProduct" GroupRef="a2ef6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:65086</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="418.6666666666666" CenterY="1246.6666666666656" Width="60.0" Height="20.0" ZOrder="33172" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000171517"/> </DataNode> <DataNode TextLabel="LPAR6" GraphId="e745c" Type="GeneProduct" GroupRef="a2ef6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67168</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="418.6666666666666" CenterY="1266.6666666666656" Width="60.0" Height="20.0" ZOrder="33174" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000139679"/> </DataNode> <DataNode TextLabel="LPAR4" GraphId="abfbc" Type="GeneProduct" GroupRef="a2ef6"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:78134</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="418.6666666666666" CenterY="1186.6666666666656" Width="60.0" Height="20.0" ZOrder="33176" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000147145"/> </DataNode> <DataNode TextLabel="GNG5" GraphId="e08b3" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:100043507</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Igf1"/> <Graphics CenterX="500.66666666666555" CenterY="1119.333333333334" Width="60.0" Height="20.0" ZOrder="33180" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000174021"/> </DataNode> <DataNode TextLabel="GNB2" GraphId="b8539" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14693</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="500.66666666666555" CenterY="1179.333333333334" Width="60.0" Height="20.0" ZOrder="33182" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000172354"/> </DataNode> <DataNode TextLabel="GNB1" GraphId="ce36b" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14688</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfa"/> <Graphics CenterX="500.66666666666555" CenterY="1159.333333333334" Width="60.0" Height="20.0" ZOrder="33184" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000078369"/> </DataNode> <DataNode TextLabel="Gm5741" GraphId="e5bb9" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">No homologues found for original id L:100503710</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="500.66666666666555" CenterY="1139.333333333334" Width="60.0" Height="20.0" ZOrder="33186" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="GNB4" GraphId="ba74e" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14696</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="500.66666666666555" CenterY="1219.3333333333342" Width="60.0" Height="20.0" ZOrder="33188" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000114450"/> </DataNode> <DataNode TextLabel="GNGT1" GraphId="bca4e" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14699</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="500.66666666666555" CenterY="1239.3333333333342" Width="60.0" Height="20.0" ZOrder="33190" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000127928"/> </DataNode> <DataNode TextLabel="GNG10" GraphId="e8d31" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14700</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="570.6666666666673" CenterY="1258.6666666666688" Width="60.0" Height="20.0" ZOrder="33192" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000242616"/> </DataNode> <DataNode TextLabel="GNG12" GraphId="ca203" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14701</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="570.6666666666673" CenterY="1278.6666666666688" Width="60.0" Height="20.0" ZOrder="33194" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000172380"/> </DataNode> <DataNode TextLabel="GNB3" GraphId="be1a4" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14695</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="500.66666666666555" CenterY="1199.333333333334" Width="60.0" Height="20.0" ZOrder="33196" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000111664"/> </DataNode> <DataNode TextLabel="GNG2" GraphId="dc261" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14702</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="570.6666666666669" CenterY="1118.6666666666688" Width="60.0" Height="20.0" ZOrder="33200" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000186469"/> </DataNode> <DataNode TextLabel="GNG3" GraphId="d8fd9" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14704</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="570.6666666666673" CenterY="1138.6666666666688" Width="60.0" Height="20.0" ZOrder="33202" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000162188"/> </DataNode> <DataNode TextLabel="GNG4" GraphId="f810f" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14706</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="570.6666666666673" CenterY="1158.6666666666688" Width="60.0" Height="20.0" ZOrder="33204" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000168243"/> </DataNode> <DataNode TextLabel="GNG5" GraphId="b220c" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14707</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="570.6666666666669" CenterY="1178.6666666666688" Width="60.0" Height="20.0" ZOrder="33206" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000174021"/> </DataNode> <DataNode TextLabel="GNG7" GraphId="b6bfd" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14708</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="570.6666666666669" CenterY="1198.6666666666688" Width="60.0" Height="20.0" ZOrder="33208" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000176533"/> </DataNode> <DataNode TextLabel="GNG8" GraphId="d9fef" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14709</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="570.6666666666669" CenterY="1218.6666666666688" Width="60.0" Height="20.0" ZOrder="33210" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000167414"/> </DataNode> <DataNode TextLabel="GNGT2" GraphId="ea6cb" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14710</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="500.66666666666555" CenterY="1259.3333333333342" Width="60.0" Height="20.0" ZOrder="33212" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000167083"/> </DataNode> <DataNode TextLabel="GNG13" GraphId="ba78e" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:64337</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="570.6666666666673" CenterY="1298.6666666666688" Width="60.0" Height="20.0" ZOrder="33214" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000127588"/> </DataNode> <DataNode TextLabel="GNG11" GraphId="b58da" Type="GeneProduct" GroupRef="da50d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:66066</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="570.6666666666673" CenterY="1238.6666666666688" Width="60.0" Height="20.0" ZOrder="33216" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000127920"/> </DataNode> <DataNode TextLabel="PIK3CG" GraphId="dbbc7" Type="GeneProduct" GroupRef="ea9b1"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:30955</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pik3cg"/> <Graphics CenterX="922.874172185432" CenterY="1182.704194260481" Width="60.0" Height="20.0" ZOrder="33218" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000105851"/> </DataNode> <DataNode TextLabel="NRAS" GraphId="b92f4" Type="GeneProduct" GroupRef="cbf0b"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18176</Comment> <Graphics CenterX="833.9999999999983" CenterY="677.6666666666634" Width="60.0" Height="20.0" ZOrder="33220" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000213281"/> </DataNode> <DataNode TextLabel="KRAS" GraphId="bb732" Type="GeneProduct" GroupRef="cbf0b"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16653</Comment> <Graphics CenterX="833.9999999999983" CenterY="657.6666666666639" Width="60.0" Height="20.0" ZOrder="33222" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000133703"/> </DataNode> <DataNode TextLabel="HRAS" GraphId="e9337" Type="GeneProduct" GroupRef="cbf0b"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15461</Comment> <Graphics CenterX="833.9999999999983" CenterY="637.6666666666645" Width="60.0" Height="20.0" ZOrder="33224" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000174775"/> </DataNode> <DataNode TextLabel="STRADA" GraphId="e4a61" Type="GeneProduct" GroupRef="fe76d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72149</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Farp2"/> <Graphics CenterX="1144.131551106774" CenterY="381.6031392415372" Width="60.0" Height="20.0" ZOrder="33236" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000266173"/> </DataNode> <DataNode TextLabel="CAB39" GraphId="fb0f6" Type="GeneProduct" GroupRef="fe76d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12283</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Farp2"/> <Graphics CenterX="1144.131551106774" CenterY="401.60313924153735" Width="60.0" Height="20.0" ZOrder="33238" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000135932"/> </DataNode> <DataNode TextLabel="CAB39L" GraphId="dbf2e" Type="GeneProduct" GroupRef="fe76d"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:69008</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Farp2"/> <Graphics CenterX="1144.131551106774" CenterY="421.6031392415376" Width="60.0" Height="20.0" ZOrder="33240" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000102547"/> </DataNode> <DataNode TextLabel="PRKAA1" GraphId="f4d05" Type="GeneProduct" GroupRef="d3a6b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:105787</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Farp2"/> <Graphics CenterX="1328.6666666666704" CenterY="381.6666666666672" Width="60.0" Height="20.0" ZOrder="33242" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000132356"/> </DataNode> <DataNode TextLabel="PRKAA2" GraphId="b6b55" Type="GeneProduct" GroupRef="d3a6b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:108079</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Farp2"/> <Graphics CenterX="1328.6666666666704" CenterY="401.66666666666737" Width="60.0" Height="20.0" ZOrder="33244" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000162409"/> </DataNode> <DataNode TextLabel="MLST8" GraphId="dae61" Type="GeneProduct" GroupRef="df6f3"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56716</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1685.9999999999986" CenterY="376.00000000000034" Width="60.0" Height="20.0" ZOrder="33246" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000167965"/> </DataNode> <DataNode TextLabel="RHEB" GraphId="ca6a6" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19744</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1549.9999999999995" CenterY="430.000000000001" Width="60.0" Height="20.0" ZOrder="33248" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000106615"/> </DataNode> <DataNode TextLabel="MTOR" GraphId="a19e6" Type="GeneProduct" GroupRef="df6f3"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56717</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1685.9999999999986" CenterY="396.0000000000007" Width="60.0" Height="20.0" ZOrder="33250" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000198793"/> </DataNode> <DataNode TextLabel="RPTOR" GraphId="a0338" Type="GeneProduct" GroupRef="df6f3"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74370</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1685.9999999999984" CenterY="416.00000000000085" Width="60.0" Height="20.0" ZOrder="33252" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000141564"/> </DataNode> <DataNode TextLabel="HIF1A" GraphId="f5d36" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15251</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1868.3333333333328" CenterY="320.9999999999992" Width="60.0" Height="20.0" ZOrder="33258" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000100644"/> </DataNode> <DataNode TextLabel="ULK1" GraphId="e1a54" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22241</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1870.3333333333337" CenterY="551.6666666666673" Width="60.0" Height="20.0" ZOrder="33260" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000177169"/> </DataNode> <DataNode TextLabel="CRTC2" GraphId="d4738" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74343</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1048.6666666666715" CenterY="1097.3333333333358" Width="60.0" Height="20.0" ZOrder="33262" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000160741"/> </DataNode> <DataNode TextLabel="CDC37" GraphId="d9fc8" Type="GeneProduct" GroupRef="b67ff"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12539</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1100.6666666666708" CenterY="1216.3333333333378" Width="60.0" Height="20.0" ZOrder="33264" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000105401"/> </DataNode> <DataNode TextLabel="HSP90AB1" GraphId="ab902" Type="GeneProduct" GroupRef="b67ff"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15516</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1100.6666666666706" CenterY="1156.3333333333355" Width="60.0" Height="20.0" ZOrder="33266" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000096384"/> </DataNode> <DataNode TextLabel="PHLPP1" GraphId="bd572" Type="GeneProduct" GroupRef="ed4a3"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:98432</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1326.6666666666658" CenterY="1128.6666666666706" Width="60.0" Height="20.0" ZOrder="33268" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000081913"/> </DataNode> <DataNode TextLabel="TCL1A" GraphId="b68eb" Type="GeneProduct" GroupRef="ef235"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21432</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1220.0000000000034" CenterY="1183.3333333333383" Width="60.0" Height="20.0" ZOrder="33270" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000100721"/> </DataNode> <DataNode TextLabel="PDPK1" GraphId="f6ee6" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18607</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1168.666666666668" CenterY="804.6666666666642" Width="60.0" Height="20.0" ZOrder="33272" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000140992"/> </DataNode> <DataNode TextLabel="Gm2436" GraphId="f5e44" Type="GeneProduct" GroupRef="bb10e"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Igf1"/> <Graphics CenterX="1196.6666666666674" CenterY="556.6666666666689" Width="60.0" Height="20.0" ZOrder="33274" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PPP2CB" GraphId="ed985" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19053</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1196.6666666666674" CenterY="618.0000000000011" Width="60.0" Height="20.0" ZOrder="33276" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000104695"/> </DataNode> <DataNode TextLabel="PPP2CA" GraphId="af651" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19052</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfa"/> <Graphics CenterX="1196.6666666666674" CenterY="598.0000000000015" Width="60.0" Height="20.0" ZOrder="33278" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000113575"/> </DataNode> <DataNode TextLabel="Gm2446" GraphId="cad00" Type="GeneProduct" GroupRef="bb10e"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1196.6666666666674" CenterY="578.0000000000017" Width="60.0" Height="20.0" ZOrder="33280" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PPP2R5D" GraphId="f981c" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21770</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1196.6666666666674" CenterY="658.0000000000003" Width="60.0" Height="20.0" ZOrder="33282" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000112640"/> </DataNode> <DataNode TextLabel="PPP2R5B" GraphId="b6e4a" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:225849</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1196.6666666666674" CenterY="677.9999999999999" Width="60.0" Height="20.0" ZOrder="33284" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000068971"/> </DataNode> <DataNode TextLabel="PPP2R2B" GraphId="fbd78" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72930</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1266.6666666666708" CenterY="697.3333333333337" Width="60.0" Height="20.0" ZOrder="33286" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000156475"/> </DataNode> <DataNode TextLabel="PPP2R1B" GraphId="a7759" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:73699</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1266.6666666666708" CenterY="717.3333333333337" Width="60.0" Height="20.0" ZOrder="33288" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000137713"/> </DataNode> <DataNode TextLabel="Ppp2r3d" GraphId="d87e8" Type="GeneProduct" GroupRef="bb10e"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1196.6666666666674" CenterY="638.0000000000007" Width="60.0" Height="20.0" ZOrder="33290" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PPP2R3A" GraphId="abfea" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:235542</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1266.6666666666704" CenterY="557.3333333333369" Width="60.0" Height="20.0" ZOrder="33292" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000073711"/> </DataNode> <DataNode TextLabel="PPP2R5C" GraphId="ca7f0" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26931</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1266.6666666666708" CenterY="577.3333333333366" Width="60.0" Height="20.0" ZOrder="33294" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000078304"/> </DataNode> <DataNode TextLabel="PPP2R5E" GraphId="dd00e" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26932</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1266.6666666666708" CenterY="597.3333333333363" Width="60.0" Height="20.0" ZOrder="33296" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000154001"/> </DataNode> <DataNode TextLabel="PPP2R2C" GraphId="b73ed" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:269643</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1266.6666666666704" CenterY="617.333333333336" Width="60.0" Height="20.0" ZOrder="33298" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000074211"/> </DataNode> <DataNode TextLabel="PPP2R1A" GraphId="bceda" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:51792</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1266.6666666666704" CenterY="637.3333333333353" Width="60.0" Height="20.0" ZOrder="33300" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000105568"/> </DataNode> <DataNode TextLabel="PPP2R2D" GraphId="cdb6a" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:52432</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1266.6666666666704" CenterY="657.333333333335" Width="60.0" Height="20.0" ZOrder="33302" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000175470"/> </DataNode> <DataNode TextLabel="PPP2R5A" GraphId="a8820" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:226849</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1196.6666666666674" CenterY="697.9999999999995" Width="60.0" Height="20.0" ZOrder="33304" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000066027"/> </DataNode> <DataNode TextLabel="PPP2R3C" GraphId="e9655" Type="GeneProduct" GroupRef="bb10e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:59032</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1266.6666666666708" CenterY="677.3333333333345" Width="60.0" Height="20.0" ZOrder="33306" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000092020"/> </DataNode> <DataNode TextLabel="HSP90AA1" GraphId="eeb5b" Type="GeneProduct" GroupRef="b67ff"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15519</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1100.6666666666706" CenterY="1176.3333333333362" Width="60.0" Height="20.0" ZOrder="33308" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000080824"/> </DataNode> <DataNode TextLabel="HSP90B1" GraphId="a147e" Type="GeneProduct" GroupRef="b67ff"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22027</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1100.6666666666706" CenterY="1196.3333333333371" Width="60.0" Height="20.0" ZOrder="33310" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000166598"/> </DataNode> <DataNode TextLabel="PHLPP2" GraphId="bad6d" Type="GeneProduct" GroupRef="ed4a3"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:244650</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1326.6666666666658" CenterY="1148.666666666672" Width="60.0" Height="20.0" ZOrder="33312" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000040199"/> </DataNode> <DataNode TextLabel="Mtcp1" GraphId="e8864" Type="GeneProduct" GroupRef="ef235"> <Comment Source="HomologyMapper">Multiple homologues found: En:ENSG00000214827;En:ENSG00000182712;</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1220.0000000000034" CenterY="1163.3333333333374" Width="60.0" Height="20.0" ZOrder="33314" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="TCL1B" GraphId="bd0cd" Type="GeneProduct" GroupRef="ef235"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:27379</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1220.0000000000034" CenterY="1203.333333333339" Width="60.0" Height="20.0" ZOrder="33316" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000213231"/> </DataNode> <DataNode TextLabel="TCL1B" GraphId="ac643" Type="GeneProduct" GroupRef="ef235"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:27380</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1220.0000000000034" CenterY="1223.3333333333399" Width="60.0" Height="20.0" ZOrder="33318" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000213231"/> </DataNode> <DataNode TextLabel="RAF1" GraphId="f5e91" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:110157</Comment> <Graphics CenterX="947.9999999999984" CenterY="658.3333333333258" Width="60.0" Height="20.0" ZOrder="33322" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000132155"/> </DataNode> <DataNode TextLabel="MAP2K2" GraphId="e9083" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26396</Comment> <Graphics CenterX="1068.0000000000023" CenterY="638.3333333333296" Width="60.0" Height="20.0" ZOrder="33324" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000126934"/> </DataNode> <DataNode TextLabel="MAP2K1" GraphId="a43d4" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26395</Comment> <Graphics CenterX="1068.0000000000023" CenterY="618.33333333333" Width="60.0" Height="20.0" ZOrder="33326" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000169032"/> </DataNode> <DataNode TextLabel="MAPK1" GraphId="dec3d" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26413</Comment> <Graphics CenterX="1068.0000000000023" CenterY="658.3333333333289" Width="60.0" Height="20.0" ZOrder="33328" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000100030"/> </DataNode> <DataNode TextLabel="MAPK3" GraphId="b33cf" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26417</Comment> <Graphics CenterX="1068.0000000000023" CenterY="678.3333333333284" Width="60.0" Height="20.0" ZOrder="33330" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000102882"/> </DataNode> <DataNode TextLabel="GSK3B" GraphId="eb5e4" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56637</Comment> <Graphics CenterX="1557.9999999999973" CenterY="704.3333333333284" Width="60.0" Height="20.0" ZOrder="33332" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000082701"/> </DataNode> <DataNode TextLabel="FOXO3" GraphId="f7c06" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56484</Comment> <Graphics CenterX="1557.9999999999989" CenterY="850.9999999999928" Width="60.0" Height="20.0" ZOrder="33334" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000118689"/> </DataNode> <DataNode TextLabel="FOXO1" GraphId="bff6d" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56458</Comment> <Graphics CenterX="1557.9999999999986" CenterY="870.999999999993" Width="60.0" Height="20.0" ZOrder="33336" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000150907"/> </DataNode> <DataNode TextLabel="IKBKB" GraphId="f8605" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16150</Comment> <Graphics CenterX="1558.000000000001" CenterY="994.9999999999939" Width="60.0" Height="20.0" ZOrder="33338" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000104365"/> </DataNode> <DataNode TextLabel="BAD" GraphId="e96b9" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12015</Comment> <Graphics CenterX="1558.6666666666672" CenterY="906.3333333333276" Width="60.0" Height="20.0" ZOrder="33340" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000002330"/> </DataNode> <DataNode TextLabel="CASP9" GraphId="d27df" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12371</Comment> <Graphics CenterX="1559.333333333334" CenterY="946.9999999999934" Width="60.0" Height="20.0" ZOrder="33342" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000132906"/> </DataNode> <DataNode TextLabel="MDM2" GraphId="d56b8" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246</Comment> <Graphics CenterX="1560.0000000000018" CenterY="1056.9999999999934" Width="60.0" Height="20.0" ZOrder="33344" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000135679"/> </DataNode> <DataNode TextLabel="IKBKG" GraphId="df200" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16151</Comment> <Graphics CenterX="1558.000000000001" CenterY="1014.999999999994" Width="60.0" Height="20.0" ZOrder="33346" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000269335"/> </DataNode> <DataNode TextLabel="CDKN1B" GraphId="d204b" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12576</Comment> <Graphics CenterX="1555.9999999999993" CenterY="779.6666666666586" Width="60.0" Height="20.0" ZOrder="33348" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000111276"/> </DataNode> <DataNode TextLabel="CDKN1A" GraphId="e6674" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12575</Comment> <Graphics CenterX="1555.9999999999993" CenterY="759.6666666666586" Width="60.0" Height="20.0" ZOrder="33350" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000124762"/> </DataNode> <DataNode TextLabel="ATF2" GraphId="d7c23" Type="GeneProduct" GroupRef="d314b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11909</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Igf1"/> <Graphics CenterX="1561.9999999999982" CenterY="1109.333333333336" Width="60.0" Height="20.0" ZOrder="33352" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000115966"/> </DataNode> <DataNode TextLabel="CREB3" GraphId="aad90" Type="GeneProduct" GroupRef="d314b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12913</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1561.9999999999984" CenterY="1189.33333333334" Width="60.0" Height="20.0" ZOrder="33354" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000107175"/> </DataNode> <DataNode TextLabel="CREB1" GraphId="fda82" Type="GeneProduct" GroupRef="d314b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12912</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfa"/> <Graphics CenterX="1561.9999999999982" CenterY="1169.3333333333399" Width="60.0" Height="20.0" ZOrder="33356" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000118260"/> </DataNode> <DataNode TextLabel="ATF4" GraphId="ce84e" Type="GeneProduct" GroupRef="d314b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11911</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1561.9999999999982" CenterY="1129.3333333333367" Width="60.0" Height="20.0" ZOrder="33358" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000128272"/> </DataNode> <DataNode TextLabel="CREB3L2" GraphId="b1204" Type="GeneProduct" GroupRef="d314b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208647</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1632.0000000000014" CenterY="1150.000000000006" Width="60.0" Height="20.0" ZOrder="33360" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000182158"/> </DataNode> <DataNode TextLabel="CREB3L3" GraphId="a1ca2" Type="GeneProduct" GroupRef="d314b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208677</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1632.0000000000014" CenterY="1170.0000000000077" Width="60.0" Height="20.0" ZOrder="33362" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000060566"/> </DataNode> <DataNode TextLabel="ATF6B" GraphId="f4774" Type="GeneProduct" GroupRef="d314b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12915</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1561.9999999999984" CenterY="1149.3333333333376" Width="60.0" Height="20.0" ZOrder="33364" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000213676"/> </DataNode> <DataNode TextLabel="CREB3L1" GraphId="d01e0" Type="GeneProduct" GroupRef="d314b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26427</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1632.000000000001" CenterY="1110.0000000000043" Width="60.0" Height="20.0" ZOrder="33366" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000157613"/> </DataNode> <DataNode TextLabel="CREB3L4" GraphId="a06a2" Type="GeneProduct" GroupRef="d314b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:78284</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1632.0000000000011" CenterY="1130.0000000000052" Width="60.0" Height="20.0" ZOrder="33368" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000143578"/> </DataNode> <DataNode TextLabel="CREB5" GraphId="aab47" Type="GeneProduct" GroupRef="d314b"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:231991</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfb"/> <Graphics CenterX="1561.9999999999982" CenterY="1209.3333333333412" Width="60.0" Height="20.0" ZOrder="33370" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000146592"/> </DataNode> <DataNode TextLabel="TBC1D1" GraphId="f64f7" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:57915</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="931.3333333333368" CenterY="197.66666666666669" Width="60.0" Height="20.0" ZOrder="33401" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000065882"/> </DataNode> <DataNode TextLabel="RAB8A" GraphId="a74cf" Type="GeneProduct" GroupRef="ccd85"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17274</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="765.3333333333376" CenterY="158.0000000000001" Width="60.0" Height="20.0" ZOrder="33403" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000167461"/> </DataNode> <DataNode TextLabel="RAB2A" GraphId="b4965" Type="GeneProduct" GroupRef="ccd85"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:59021</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="765.3333333333376" CenterY="217.9999999999998" Width="60.0" Height="20.0" ZOrder="33405" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000104388"/> </DataNode> <DataNode TextLabel="RAB10" GraphId="f2243" Type="GeneProduct" GroupRef="ccd85"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19325</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="765.3333333333376" CenterY="178.0" Width="60.0" Height="20.0" ZOrder="33407" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000084733"/> </DataNode> <DataNode TextLabel="RAB11B" GraphId="ede66" Type="GeneProduct" GroupRef="ccd85"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19326</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="765.3333333333376" CenterY="197.99999999999991" Width="60.0" Height="20.0" ZOrder="33409" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000185236"/> </DataNode> <DataNode TextLabel="RAB14" GraphId="d1212" Type="GeneProduct" GroupRef="ccd85"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:68365</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="765.3333333333376" CenterY="237.99999999999972" Width="60.0" Height="20.0" ZOrder="33411" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000119396"/> </DataNode> <DataNode TextLabel="SLC2A4" GraphId="fa0f4" Type="GeneProduct" GroupRef="dff1c"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20528</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="463.3333333333376" CenterY="132.00000000000006" Width="60.0" Height="20.0" ZOrder="33413" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000181856"/> </DataNode> <DataNode TextLabel="SLC2A1" GraphId="b1f4d" Type="GeneProduct" GroupRef="dff1c"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20525</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="463.3333333333376" CenterY="72.00000000000006" Width="60.0" Height="20.0" ZOrder="33415" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000117394"/> </DataNode> <DataNode TextLabel="SLC2A3" GraphId="be884" Type="GeneProduct" GroupRef="dff1c"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20527</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="463.3333333333376" CenterY="112.00000000000006" Width="60.0" Height="20.0" ZOrder="33417" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000059804"/> </DataNode> <DataNode TextLabel="SLC2A2" GraphId="d70da" Type="GeneProduct" GroupRef="dff1c"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20526</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="463.3333333333376" CenterY="92.00000000000006" Width="60.0" Height="20.0" ZOrder="33419" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000163581"/> </DataNode> <DataNode TextLabel="PPARGC1A" GraphId="afb14" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19017</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="857.3333333333367" CenterY="78.00000000000023" Width="60.0" Height="20.0" ZOrder="33423" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000109819"/> </DataNode> <DataNode TextLabel="GYS1" GraphId="f0c13" Type="GeneProduct" GroupRef="d3a49"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14936</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1713.3333333333371" CenterY="132.33333333333348" Width="60.0" Height="20.0" ZOrder="33429" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000104812"/> </DataNode> <DataNode TextLabel="GYS2" GraphId="ad73e" Type="GeneProduct" GroupRef="d3a49"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:232493</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1713.3333333333371" CenterY="152.33333333333331" Width="60.0" Height="20.0" ZOrder="33431" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000111713"/> </DataNode> <DataNode TextLabel="PFKFB2" GraphId="a6eb7" Type="GeneProduct" GroupRef="bae3f"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18640</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1751.0000000000032" CenterY="234.9999999999998" Width="60.0" Height="20.0" ZOrder="33433" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000123836"/> </DataNode> <DataNode TextLabel="PFKFB1" GraphId="c3f0b" Type="GeneProduct" GroupRef="bae3f"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18639</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1751.0000000000032" CenterY="214.9999999999999" Width="60.0" Height="20.0" ZOrder="33435" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000158571"/> </DataNode> <DataNode TextLabel="PFKFB3" GraphId="d5b60" Type="GeneProduct" GroupRef="bae3f"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:170768</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1751.0000000000032" CenterY="255.0000000000001" Width="60.0" Height="20.0" ZOrder="33437" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000170525"/> </DataNode> <DataNode TextLabel="PFKFB4" GraphId="cc143" Type="GeneProduct" GroupRef="bae3f"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:270198</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1751.0000000000032" CenterY="275.0000000000005" Width="60.0" Height="20.0" ZOrder="33439" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000114268"/> </DataNode> <DataNode TextLabel="LIPE" GraphId="dc8a8" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16890</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1480.0000000000057" CenterY="91.6666666666667" Width="60.0" Height="20.0" ZOrder="33441" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000079435"/> </DataNode> <DataNode TextLabel="SREBF1" GraphId="ae5b6" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20787</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1407.0000000000055" CenterY="90.66666666666687" Width="60.0" Height="20.0" ZOrder="33443" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000072310"/> </DataNode> <DataNode TextLabel="FOXA1" GraphId="f8442" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15375</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1557.333333333339" CenterY="90.6666666666667" Width="60.0" Height="20.0" ZOrder="33445" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000129514"/> </DataNode> <DataNode TextLabel="ACACA" GraphId="d1026" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:107476</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1315.000000000005" CenterY="91.66666666666677" Width="60.0" Height="20.0" ZOrder="33447" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000278540"/> </DataNode> <DataNode TextLabel="ELAVL1" GraphId="cad44" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15568</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1632.333333333339" CenterY="90.6666666666667" Width="60.0" Height="20.0" ZOrder="33471" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000066044"/> </DataNode> <DataNode TextLabel="NOS1" GraphId="e3684" Type="GeneProduct" GroupRef="ecf10"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18125</Comment> <Graphics CenterX="1565.9999999999986" CenterY="1276.9999999999927" Width="60.0" Height="20.0" ZOrder="33473" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000089250"/> </DataNode> <DataNode TextLabel="EPAS1" GraphId="edc48" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13819</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1868.3333333333328" CenterY="340.9999999999992" Width="60.0" Height="20.0" ZOrder="33532" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000116016"/> </DataNode> <DataNode TextLabel="HIF3A" GraphId="dcf83" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53417</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1868.3333333333328" CenterY="360.9999999999992" Width="60.0" Height="20.0" ZOrder="33534" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000124440"/> </DataNode> <DataNode TextLabel="RPS6KB2" GraphId="cf118" Type="GeneProduct" GroupRef="f30ec"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:58988</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1866.6666666666667" CenterY="416.99999999999955" Width="60.0" Height="20.0" ZOrder="33542" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000175634"/> </DataNode> <DataNode TextLabel="EIF4EBP1" GraphId="db051" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13685</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1868.2727272727275" CenterY="478.7878787878791" Width="55.999999999999545" Height="20.0" ZOrder="33544" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000187840"/> </DataNode> <DataNode TextLabel="EIF4B" GraphId="d2416" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75705</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1973.0000000000005" CenterY="424.3333333333335" Width="60.0" Height="20.0" ZOrder="33546" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000063046"/> </DataNode> <DataNode TextLabel="RPS6KB1" GraphId="c93b6" Type="GeneProduct" GroupRef="f30ec"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72508</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1866.6666666666667" CenterY="396.99999999999955" Width="60.0" Height="20.0" ZOrder="33548" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000108443"/> </DataNode> <DataNode TextLabel="RPS6" GraphId="f5969" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20104</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1972.0000000000005" CenterY="392.3333333333335" Width="60.0" Height="20.0" ZOrder="33550" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000137154"/> </DataNode> <DataNode TextLabel="EIF4E" GraphId="a7b66" Type="GeneProduct" GroupRef="bcbcc"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13684</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1971.0000000000005" CenterY="458.3333333333335" Width="60.0" Height="20.0" ZOrder="33552" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000151247"/> </DataNode> <DataNode TextLabel="EIF4E2" GraphId="ad509" Type="GeneProduct" GroupRef="bcbcc"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26987</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1971.0000000000005" CenterY="478.3333333333335" Width="60.0" Height="20.0" ZOrder="33554" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000135930"/> </DataNode> <DataNode TextLabel="EIF4E1B" GraphId="e8eab" Type="GeneProduct" GroupRef="bcbcc"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:218268</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Arhgap5"/> <Graphics CenterX="1971.0000000000005" CenterY="498.3333333333335" Width="60.0" Height="20.0" ZOrder="33556" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000175766"/> </DataNode> <DataNode TextLabel="PIK3C2B" GraphId="b5331" Type="GeneProduct" GroupRef="d656f"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:240752</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pik3cg"/> <Graphics CenterX="916.6666666666682" CenterY="1041.38410596026" Width="60.0" Height="20.0" ZOrder="33560" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000133056"/> </DataNode> <DataNode TextLabel="PIK3C2A" GraphId="b062e" Type="GeneProduct" GroupRef="d656f"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18704</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pik3cg"/> <Graphics CenterX="916.6666666666682" CenterY="1021.3841059602601" Width="60.0" Height="20.0" ZOrder="33562" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000011405"/> </DataNode> <DataNode TextLabel="Pik3c2g" GraphId="d58d9" Type="GeneProduct" GroupRef="d656f"> <Comment Source="HomologyMapper">No homologues found for original id L:18705</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pik3cg"/> <Graphics CenterX="916.6666666666682" CenterY="1061.38410596026" Width="60.0" Height="20.0" ZOrder="33564" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="IRS1" GraphId="ad56c" Type="GeneProduct" GroupRef="a4c16"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16367</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfa"/> <Graphics CenterX="705.1176470588233" CenterY="807.8235294117627" Width="60.0" Height="20.0" ZOrder="33568" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000169047"/> </DataNode> <DataNode TextLabel="IRS4" GraphId="fd60d" Type="GeneProduct" GroupRef="a4c16"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16370</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfa"/> <Graphics CenterX="705.1176470588233" CenterY="867.8235294117627" Width="60.0" Height="20.0" ZOrder="33570" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000133124"/> </DataNode> <DataNode TextLabel="Irs3" GraphId="f1916" Type="GeneProduct" GroupRef="a4c16"> <Comment Source="HomologyMapper">No homologues found for original id L:16369</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfa"/> <Graphics CenterX="705.1176470588233" CenterY="847.8235294117627" Width="60.0" Height="20.0" ZOrder="33572" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="IRS2" GraphId="c5a8e" Type="GeneProduct" GroupRef="a4c16"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:384783</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Pdgfa"/> <Graphics CenterX="705.1176470588233" CenterY="827.8235294117627" Width="60.0" Height="20.0" ZOrder="33574" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000185950"/> </DataNode> <DataNode TextLabel="Insr" GraphId="a850b" Type="GeneProduct"> <Comment Source="GenMAPP remarks">GRB2; growth factor receptor-bound protein 2</Comment> <Graphics CenterX="464.3333333333321" CenterY="863.7254901960783" Width="60.0" Height="20.0" ZOrder="33580" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="Ins1" GraphId="d9444" Type="GeneProduct" GroupRef="bc4df"> <Comment Source="GenMAPP remarks">GRB2; growth factor receptor-bound protein 2</Comment> <Graphics CenterX="358.3333333333319" CenterY="853.2549019607843" Width="60.0" Height="20.0" ZOrder="33582" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="Ins2" GraphId="dd343" Type="GeneProduct" GroupRef="bc4df"> <Comment Source="GenMAPP remarks">GRB2; growth factor receptor-bound protein 2</Comment> <Graphics CenterX="358.333333333332" CenterY="873.2549019607843" Width="60.0" Height="20.0" ZOrder="33584" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <State GraphRef="e0405" TextLabel="P" GraphId="ca8ba"> <Graphics RelX="1.0" RelY="1.0" Width="15.0" Height="15.0" ShapeType="Oval"/> <Xref Database="" ID=""/> </State> <State GraphRef="b8326" TextLabel="P" GraphId="afdd5"> <Graphics RelX="1.0" RelY="1.0" Width="15.0" Height="15.0" ShapeType="Oval"/> <Xref Database="" ID=""/> </State> <State GraphRef="c2c18" TextLabel="P" GraphId="ba5f4"> <Graphics RelX="1.0" RelY="1.0" Width="15.0" Height="15.0" ShapeType="Oval"/> <Xref Database="" ID=""/> </State> <State GraphRef="eb5e4" TextLabel="P" GraphId="e0ac7"> <Graphics RelX="1.0" RelY="1.0" Width="15.0" Height="15.0" ShapeType="Oval"/> <Xref Database="" ID=""/> </State> <State GraphRef="f7c06" TextLabel="P" GraphId="fddba"> <Graphics RelX="1.0" RelY="1.0" Width="15.0" Height="15.0" ShapeType="Oval"/> <Xref Database="" ID=""/> </State> <State GraphRef="bff6d" TextLabel="P" GraphId="b54b3"> <Graphics RelX="1.0" RelY="1.0" Width="15.0" Height="15.0" ShapeType="Oval"/> <Xref Database="" ID=""/> </State> <State GraphRef="f8605" TextLabel="P" GraphId="ba30b"> <Graphics RelX="1.0" RelY="1.0" Width="15.0" Height="15.0" ShapeType="Oval"/> <Xref Database="" ID=""/> </State> <State GraphRef="e96b9" TextLabel="P" GraphId="e4842"> <Graphics RelX="1.0" RelY="1.0" Width="15.0" Height="15.0" ShapeType="Oval"/> <Xref Database="" ID=""/> </State> <State GraphRef="d27df" TextLabel="P" GraphId="a04af"> <Graphics RelX="1.0" RelY="1.0" Width="15.0" Height="15.0" ShapeType="Oval"/> <Xref 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