Insulin-like Growth Factor-2 mRNA Binding Proteins binding to RNA (Homo sapiens)

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<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Insulin-like Growth Factor-2 mRNA Binding Proteins binding to RNA" Organism="Homo sapiens"> <Comment Source="WikiPathways-description">Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs) bind specific sets of RNA and regulate their translation, stability, and subcellular localization. IGF2BP1, IGF2BP2, and IGF2BP3 bind about 8400 protein-coding transcripts. The target RNAs contain the sequence motif CAUH (where H is A, U, or, C) and binding of IGFBPs increases the stability of the target RNAs. View original pathway at [http://www.reactome.org/PathwayBrowser/#DIAGRAM=428359 Reactome].</Comment> <Comment Source="Reactome-Converter">Pathway is converted from Reactome ID: 428359</Comment> <Comment Source="Reactome-version">Reactome version: 75</Comment> <Comment Source="Reactome Author">Reactome Author: May, Bruce</Comment> <BiopaxRef>bc9</BiopaxRef> <BiopaxRef>f0c</BiopaxRef> <BiopaxRef>a56</BiopaxRef> <BiopaxRef>e3b</BiopaxRef> <BiopaxRef>a18</BiopaxRef> <BiopaxRef>c2c</BiopaxRef> <Attribute Key="reactome_id" Value="428359"/> <Graphics BoardWidth="1110.0" BoardHeight="1235.0"/> <DataNode TextLabel="IGF2-002 mRNA " GraphId="a5077" Type="Protein" GroupRef="baf4b"> <Attribute Key="cellular_location" Value="cytosol"/> <Attribute Key="complex_id" Value="R-HSA-428310"/> <Attribute Key="copies_num" Value="1"/> <Graphics CenterX="240.0" CenterY="1195.0" Width="100.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENST00000337883"/> 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<bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="cd0"> <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">16306994</bp:ID> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1.</bp:TITLE> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hüttelmaier S, Zenklusen D, Lederer M, Dictenberg J, Lorenz M, Meng X, Bassell GJ, Condeelis J, Singer RH.</bp:AUTHORS> </bp:PublicationXref> <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="bc9"> <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">11713986</bp:ID> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE 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rdf:id="d09"> <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">12024010</bp:ID> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Regulation of c-myc mRNA decay by translational pausing in a coding region instability determinant.</bp:TITLE> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Lemm I, Ross J.</bp:AUTHORS> </bp:PublicationXref> <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="e3b"> <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">17652133</bp:ID> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VICKZ proteins mediate cell migration via their RNA binding activity.</bp:TITLE> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Oberman F, Rand 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Return to Insulin-like Growth Factor-2 mRNA Binding Proteins binding to RNA (Homo sapiens).