Help:WikiPathways Webservice

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{|style="clear:left, right" align="right"
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= Web Services for WikiPathways =
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|__TOC__
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= The WikiPathways web service =
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WikiPathways can be accessed programmatically through a REST web service. These services provide powerful means to query, access and interact with the pathway content at WikiPathways.  
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WikiPathways can be accessed through a [[wikipedia:SOAP|SOAP]] web service. This page provides documentation and examples of what you can do with the web service.
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|rowspan="2" valign="top"|__TOC__
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== Showcase ==
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Click on one of the images below for examples on what you can do with the WikiPathways web service.
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{|style="width:75%;" border="0" valign="top" cellspacing="5" cellpadding="1"
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|align="center"|<big>'''Search'''</big>{{#imgLink:WikiPathwaysSearch.png|125|center||Help|{{FULLPAGENAME}}/WikiPathwaysSearch|Search}}
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''Use the web service to search for pathways''
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|align="center"|<big>'''Integrate'''</big>{{#imgLink:AtlasMapper.png|125|center||Help|{{FULLPAGENAME}}/AtlasMapper|Integrate}}
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''Integrate pathway information with gene expression data''
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  |align="center"|<big>'''Query interactions'''</big>{{#imgLink:Cytoscape.png|125|center||Help|{{FULLPAGENAME}}/Cytoscape|Cytoscape}}
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''Load pathways as interaction networks in Cytoscape''
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|align="center"|<big>'''Build workflows'''</big>{{#imgLink:Taverna.png|125|center||Help|{{FULLPAGENAME}}/Taverna|Taverna}}
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''Use pathway information in your Taverna workflows''
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|}
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== Getting Started ==
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== API Reference ==
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The web service is described in a WSDL file that is located at:
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See the [https://webservice.wikipathways.org Swagger] page for a list of available web service functions and data structures.
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[http://www.wikipathways.org/wpi/webservice/webservice.php?wsdl http://www.wikipathways.org/wpi/webservice/webservice.php?wsdl]
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=== Java libraries ===
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You can try out the WikiPathways web service quickly, by loading this WSDL file in [http://www.soapui.org/ SoapUI], a tool for testing web services.
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You can get a high-level API to the WikiPathways web service here: [http://developers.pathvisio.org/browser/trunk/modules/org.wikipathways.client source] [http://developers.pathvisio.org/data/releases compiled binaries] (choose the most recent wikipathways_client_bin-*).
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== API Reference ==
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See the [[{{FULLPAGENAME}}/API|API reference]] page for a list of available web service functions and data structures.
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=== Java libraries for WikiPathways ===
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* [http://svn.bigcat.unimaas.nl/pathvisio/trunk/tools/wikipathways-client wikipathways-client]: A high-level API to the WikiPathways web service.
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* [http://svn.bigcat.unimaas.nl/pathvisio/trunk/ PathVisio libraries]: Libraries to process GPML and use the synonym databases.
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=== Working with GPML ===
=== Working with GPML ===
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The pathways on WikiPathways are stored in the GPML format. This is an XML format and can be processed in any programming language. See [http://www.pathvisio.org/EverythingGPML here] for the GPML specification. If you are developing in Java, we recommend using the [[#Java libraries for WikiPathways|PathVisio library]].
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The pathways on WikiPathways are stored in the GPML format. This is an XML format and can be processed in any programming language. See [http://developers.pathvisio.org/wiki/EverythingGpml here] for the GPML specification. If you are developing in Java, we recommend using our [[#Java libraries|Java libraries]].
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=== SOAP libraries ===
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For most programming languages, libraries exist to make working with SOAP web service easier. Below is a short list of SOAP libraries for popular programming languages that might help you work with the WikiPathways web service.
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* Java:
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** [http://ws.apache.org/axis/java/index.html Apache Axis]
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** See the [[#java|Java section]] for information on writing Java tools for the web service
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* Perl:
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** [http://www.soaplite.com/ SOAP::Lite]
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* Php:
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** [http://nl.php.net/soap SOAP] (official php soap library)
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** [http://phpsoaptoolkit.sourceforge.net/phpsoap/ PHP-SOAP]
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* Python:
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** [http://pywebsvcs.sourceforge.net/ SOAPpy]
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** [http://trac.optio.webfactional.com/ soaplib]
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* R
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** [http://www.omegahat.org/SSOAP/ SSOAP]
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== Examples ==
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Below you find some small example scripts in various languages that may help to get you started.
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=== Java ===
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Use the [[#Java libraries for WikiPathways|wikipathways-client and PathVisio libraries]] to access the WikiPathways web service from Java. Below is a short example program in Java.
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<pre>
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package org.pathvisio.wikipathways;
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import java.net.URL;
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import org.pathvisio.model.DataSource;
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import org.pathvisio.model.ObjectType;
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import org.pathvisio.model.Pathway;
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import org.pathvisio.model.PathwayElement;
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import org.pathvisio.model.Xref;
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import org.pathvisio.wikipathways.webservice.WSPathway;
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import org.pathvisio.wikipathways.webservice.WSPathwayInfo;
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import org.pathvisio.wikipathways.webservice.WSSearchResult;
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public class Example {
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public static void main(String[] args) {
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try {
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//Create a client to the WikiPathways web service
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WikiPathwaysClient client = new WikiPathwaysClient(
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new URL("http://www.wikipathways.org/wpi/webservice/webservice.php")
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);
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//Find a pathway by affymetrix probeset
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Xref affy = new Xref("at_1234", DataSource.AFFY);
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System.out.println("Searching for pathways with Affymetrix probeset " + affy);
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WSSearchResult[] result = client.findPathwaysByXref(affy);
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for(WSSearchResult r : result) {
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System.out.println("Found pathway: " + r.getName() + " (" + r.getSpecies() + ")");
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}
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//Download a pathway from WikiPathways
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WSPathway wsPathway = client.getPathway("WP274");
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System.out.println("Downloaded pathway " + wsPathway.getName() +
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", revision " + wsPathway.getRevision());
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//Create a pathway object
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Pathway pathway = WikiPathwaysClient.toPathway(wsPathway);
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//Get all genes, proteins and metabolites for a pathway
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for(PathwayElement pwElm : pathway.getDataObjects()) {
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//Only take elements with type DATANODE (genes, proteins, metabolites)
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if(pwElm.getObjectType() == ObjectType.DATANODE) {
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//Print information to the screen
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System.out.println(pwElm.getTextLabel());
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System.out.println("\t" + pwElm.getXref());
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System.out.println("\t" + pwElm.getDataNodeType());
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}
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}
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//Save the pathway locally
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pathway.writeToXml(new File(wsPathway.getName() + ".gpml"));
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//Print info for all WikiPathways pathways
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WSPathwayInfo[] pathwayList = client.listPathways();
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for(WSPathwayInfo pathwayInfo : pathwayList) {
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System.out.println("Pathway:");
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System.out.println("\tIdentifier:\t" + pathwayInfo.getId());
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System.out.println("\tName:\t" + pathwayInfo.getName());
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System.out.println("\tOrganism:\t" + pathwayInfo.getSpecies());
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}
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} catch(Exception e) {
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e.printStackTrace();
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}
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}
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}
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</pre>
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=== R ===
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Using the [http://www.omegahat.org/SSOAP/ SSOAP] package in [http://www.r-project.org R], you can retrieve pathway information from the WikiPathways web service and use it in your R scripts (e.g. for gene set enrichment or pathway statistics). Below are a few code snippets that show you how to use SSOAP with the WikiPathways web service.
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<pre><nowiki>
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## Install SSOAP from Bioconductor ##
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source("http://bioconductor.org/biocLite.R")
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biocLite("SSOAP")
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## Load the SSOAP library ##
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=== Libraries ===
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library(SSOAP)
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Below is a short list of libraries for popular programming languages that might help you work with the WikiPathways web service.
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## Create a SOAPServer instance for the web service ##
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* R: The rWikiPathways package with vignettes at [https://bioconductor.org/packages/release/bioc/html/rWikiPathways.html bioconductor].
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srv = SOAPServer("http://www.wikipathways.org/wpi/webservice/webservice.php");
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* Java: Java API client with code examples at [https://github.com/wikipathways/wikipathways-api-client-java github].
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* Perl: Perl API client with code examples at [https://github.com/wikipathways/wikipathways-api-client-perl github].
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* Php: Example scripts at [https://github.com/wikipathways/scripts/ github].
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* Python: Python API client with code examples at [https://github.com/wikipathways/wikipathways-api-client-py github].
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## List all organisms on WikiPathways ##
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== Other Examples ==
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reply = .SOAP(srv, "listOrganisms", action=I("listOrganisms"), handlers=NULL)
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doc = xmlParse(reply$content, asText=TRUE)
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organismNodes = xmlElementsByTagName(xmlRoot(doc), "organisms", TRUE)
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for(node in organismNodes) {
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=== Groovy ===
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print(xmlValue(node)) #Print the organism name to the screen
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}
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## Find all pathways for the 'apoptosis' keyword ##
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[http://www.helixsoft.nl/blog/?p=153 This blog post] contains an example of how to use the WikiPathways webservice in Groovy.
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reply = .SOAP(srv, "findPathwaysByText", query="apoptosis", species="", action=I("findPathwaysByText"), handlers=NULL)
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doc = xmlParse(reply$content, asText=TRUE)
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# Find the result nodes with an xpath query
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== How to cite ==
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resultNodes = getNodeSet(doc, "//*[local-name()='result']")
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Kelder T, Pico AR, Hanspers K, van Iersel MP, Evelo C, Conklin BR. (2009) '''Mining Biological Pathways Using WikiPathways Web Services.''' PLoS ONE 4(7): [http://www.plosone.org/article/info:doi/10.1371/journal.pone.0006447 doi:10.1371/journal.pone.0006447]
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# Print the pathway name, species and url for each result
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for(node in resultNodes) {
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children = xmlChildren(node, addNames= TRUE)
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url = xmlValue(children$url)
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name = xmlValue(children$name);
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species = xmlValue(children$species);
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print(paste(name, " (", species, "): ", url, sep=""))
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}
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</nowiki></pre>
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-----
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<p>[[:Help:Contents|Return to Help Contents]]</p>
<p>[[:Help:Contents|Return to Help Contents]]</p>
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<p>[[:Help:Frequently_Asked_Questions|Continue to FAQ]]</p>
 

Current revision

Web Services for WikiPathways

WikiPathways can be accessed programmatically through a REST web service. These services provide powerful means to query, access and interact with the pathway content at WikiPathways.

Contents

API Reference

See the Swagger page for a list of available web service functions and data structures.

Java libraries

You can get a high-level API to the WikiPathways web service here: source compiled binaries (choose the most recent wikipathways_client_bin-*).

Working with GPML

The pathways on WikiPathways are stored in the GPML format. This is an XML format and can be processed in any programming language. See here for the GPML specification. If you are developing in Java, we recommend using our Java libraries.

Libraries

Below is a short list of libraries for popular programming languages that might help you work with the WikiPathways web service.

  • R: The rWikiPathways package with vignettes at bioconductor.
  • Java: Java API client with code examples at github.
  • Perl: Perl API client with code examples at github.
  • Php: Example scripts at github.
  • Python: Python API client with code examples at github.

Other Examples

Groovy

This blog post contains an example of how to use the WikiPathways webservice in Groovy.

How to cite

Kelder T, Pico AR, Hanspers K, van Iersel MP, Evelo C, Conklin BR. (2009) Mining Biological Pathways Using WikiPathways Web Services. PLoS ONE 4(7): doi:10.1371/journal.pone.0006447

Return to Help Contents
Retrieved from "https://classic.wikipathways.org/index.php/Help:WikiPathways_Webservice"
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