Portal:IEM/CoveredPathways
From WikiPathways
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! Chapter ed. 5 || Title || Links WP || Chapter ed. 4 || Status || Diseases: x from ch. ed. 4 <br/> (+y) from other ch. | ! Chapter ed. 5 || Title || Links WP || Chapter ed. 4 || Status || Diseases: x from ch. ed. 4 <br/> (+y) from other ch. | ||
|- | |- | ||
| - | | 13 || Disorders of pyrimidine and purine metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4225 WP4225] and [https://www.wikipathways.org/index.php/Pathway:WP4224 WP4224] || 41 || style="font-style: italic; color: blue;" | Approved | + | | 13 || Disorders of pyrimidine and purine metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4225 WP4225] and [https://www.wikipathways.org/index.php/Pathway:WP4224 WP4224] || 41 || style="font-style: italic; color: blue;" | Approved (ed.5) |
| + | |- | ||
| + | | 14 || Disorders of Nucleotide Metabolism || || || style="font-style: italic; color: blue;" | | ||
|- | |- | ||
| 15 || Creatine disorders || [https://www.wikipathways.org/index.php/Pathway:WP5190 WP5190] || 32 || style="font-style: italic; color: blue;" | Approved | | 15 || Creatine disorders || [https://www.wikipathways.org/index.php/Pathway:WP5190 WP5190] || 32 || style="font-style: italic; color: blue;" | Approved | ||
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| 17 || Disorders of ammonia detoxification || style="font-style: italic; color: red;" | [https://www.wikipathways.org/index.php/Pathway:WP4595 WP4595] || 4 || style="font-style: italic; color: blue;" | Approved | | 17 || Disorders of ammonia detoxification || style="font-style: italic; color: red;" | [https://www.wikipathways.org/index.php/Pathway:WP4595 WP4595] || 4 || style="font-style: italic; color: blue;" | Approved | ||
|- | |- | ||
| - | | 18 || Disorders of amino acid transport || style="font-style: italic; color: red;" | [https://www.wikipathways.org/index.php/Pathway:WP5029 WP5029] || 6 || style="font-style: italic; color: | + | | 18 || Disorders of amino acid transport || style="font-style: italic; color: red;" | [https://www.wikipathways.org/index.php/Pathway:WP5029 WP5029] || 6 || style="font-style: italic; color: blue;" | Approved |
|- | |- | ||
| - | | 19 || Disorders of monoamine metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4220 WP4220] || 31|| style="font-style: italic; color: blue;" | Approved | + | | 19 || Disorders of monoamine metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4220 WP4220] || 31|| style="font-style: italic; color: blue;" | Approved (ed.5) || 6, non missing |
|- | |- | ||
| 20 || Disorders of phenylalanine and tetrahydrobiopterin metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4156 WP4156] || 1|| style="font-style: italic; color: blue;" | Approved (ed.5) || 8 (+2), non missing | | 20 || Disorders of phenylalanine and tetrahydrobiopterin metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4156 WP4156] || 1|| style="font-style: italic; color: blue;" | Approved (ed.5) || 8 (+2), non missing | ||
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| 23 || Disorders of branched-chain amino acid metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4686 WP4686] || 7|| style="font-style: italic; color: blue;" | Approved | | 23 || Disorders of branched-chain amino acid metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4686 WP4686] || 7|| style="font-style: italic; color: blue;" | Approved | ||
|- | |- | ||
| - | | 24 || Disorders of Beta and Gamma Amino Acids|| Fig.24.2: [https://www.wikipathways.org/index.php/Pathway:WP4157 WP4157] || 5 (Fig.5.3)|| style="font-style: italic; color: blue;" | Approved || 2, non missing | + | | 24 || Disorders of Beta and Gamma Amino Acids|| Fig.24.2: [https://www.wikipathways.org/index.php/Pathway:WP4157 WP4157] || 5 (Fig.5.3)|| style="font-style: italic; color: blue;" | Approved (ed.5)|| 2, non missing |
|- | |- | ||
| 26 || Disorders of glycine metabolism || Fig.5.1:[https://www.wikipathways.org/index.php/Pathway:WP5028 WP5028], <br/> Fig.5.4: [https://www.wikipathways.org/index.php/Pathway:WP5026 WP5026] || 5|| style="font-style: italic; color: orange;" | In Progress | | 26 || Disorders of glycine metabolism || Fig.5.1:[https://www.wikipathways.org/index.php/Pathway:WP5028 WP5028], <br/> Fig.5.4: [https://www.wikipathways.org/index.php/Pathway:WP5026 WP5026] || 5|| style="font-style: italic; color: orange;" | In Progress | ||
|- | |- | ||
| 26 || Disorders of glycine metabolism || Fig.5.2: [https://www.wikipathways.org/index.php/Pathway:WP4688 WP4688] || 5|| style="font-style: italic; color: blue;" | Approved | | 26 || Disorders of glycine metabolism || Fig.5.2: [https://www.wikipathways.org/index.php/Pathway:WP4688 WP4688] || 5|| style="font-style: italic; color: blue;" | Approved | ||
| + | |- | ||
| + | | 27 || Disorders of Lipoic Acid and Iron-Sulphur Protein Metabolism || || || style="font-style: italic; color: blue;" | | ||
|- | |- | ||
| 28 || Disorders of cobalamin metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4271 WP4271] || 13|| style="font-style: italic; color: blue;" | Approved | | 28 || Disorders of cobalamin metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4271 WP4271] || 13|| style="font-style: italic; color: blue;" | Approved | ||
|- | |- | ||
| - | | 29 || Disorders of folate metabolism|| [https://www.wikipathways.org/index.php/Pathway:WP4259 WP4259] and [https://www.wikipathways.org/index.php/Pathway:WP4288 WP4288] || 10|| style="font-style: italic; color: blue;" | Approved | + | | 29 || Disorders of folate metabolism|| [https://www.wikipathways.org/index.php/Pathway:WP4259 WP4259] and [https://www.wikipathways.org/index.php/Pathway:WP4288 WP4288] || 10|| style="font-style: italic; color: blue;" | Approved || 9 (+3), non missing |
| + | |- | ||
|- | |- | ||
| 30 || Disorders of biotin metabolism|| [https://www.wikipathways.org/index.php/Pathway:WP5031 WP5031] || 14|| style="font-style: italic; color: blue;" | Approved | | 30 || Disorders of biotin metabolism|| [https://www.wikipathways.org/index.php/Pathway:WP5031 WP5031] || 14|| style="font-style: italic; color: blue;" | Approved | ||
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| 32 || Disorders of riboflavin metabolism || [https://www.wikipathways.org/index.php/Pathway:WP5037 WP5037] || 16|| style="font-style: italic; color: blue;" | Approved | | 32 || Disorders of riboflavin metabolism || [https://www.wikipathways.org/index.php/Pathway:WP5037 WP5037] || 16|| style="font-style: italic; color: blue;" | Approved | ||
|- | |- | ||
| - | | 34 || Vitamin B6 -Dependent and Responsive Disorders || [https://www.wikipathways.org/index.php/Pathway:WP4228 WP4228] || 11|| style="font-style: italic; color: blue;" | Approved | + | | 33 || Disorders of Niacin, NAD, and Pantothenate Metabolism || || || style="font-style: italic; color: blue;" | |
| + | |- | ||
| + | | 34 || Vitamin B6 -Dependent and Responsive Disorders || [https://www.wikipathways.org/index.php/Pathway:WP4228 WP4228] || 11|| style="font-style: italic; color: blue;" | Approved (ed.5) || 5, non missing | ||
|- | |- | ||
| 35 || Disorders of molybdenum metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4507 WP4507] and [https://www.wikipathways.org/index.php/Pathway:WP4504 WP4504] || 12|| style="font-style: italic; color: blue;" | Approved | | 35 || Disorders of molybdenum metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4507 WP4507] and [https://www.wikipathways.org/index.php/Pathway:WP4504 WP4504] || 12|| style="font-style: italic; color: blue;" | Approved | ||
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|- | |- | ||
| 37 || Iron metabolism disorder || [https://www.wikipathways.org/index.php/Pathway:WP5172 WP5172] || 40 || style="font-style: italic; color: blue;" | Approved | | 37 || Iron metabolism disorder || [https://www.wikipathways.org/index.php/Pathway:WP5172 WP5172] || 40 || style="font-style: italic; color: blue;" | Approved | ||
| + | |- | ||
| + | | 38 || Disorders of Manganese Metabolism || || || style="font-style: italic; color: blue;" | | ||
|- | |- | ||
| 39 || Disorders of carbohydrate and glucose transport || Fig.18.3:[https://www.wikipathways.org/index.php/Pathway:WP5173 WP5173], <br/> Fig.18.4: [https://www.wikipathways.org/index.php/Pathway:WP5178 WP5178] || 18 || style="font-style: italic; color: blue;" | Approved | | 39 || Disorders of carbohydrate and glucose transport || Fig.18.3:[https://www.wikipathways.org/index.php/Pathway:WP5173 WP5173], <br/> Fig.18.4: [https://www.wikipathways.org/index.php/Pathway:WP5178 WP5178] || 18 || style="font-style: italic; color: blue;" | Approved | ||
| + | |- | ||
| + | | 40 || Disorders of Pentose Phosphate Pathway and Polyol Metabolism || || || style="font-style: italic; color: blue;" | | ||
| + | |- | ||
| + | | 41 || Disorders Congenital Hyperinsulinism || || || style="font-style: italic; color: blue;" | | ||
|- | |- | ||
| 42 || Disorders of pyruvate and Krebs cycle metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4236 WP4236] || 20|| style="font-style: italic; color: blue;" | Approved | | 42 || Disorders of pyruvate and Krebs cycle metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4236 WP4236] || 20|| style="font-style: italic; color: blue;" | Approved | ||
| + | |- | ||
| + | | 43 || Disorders of Mitochondrial Carriers || || || style="font-style: italic; color: blue;" | | ||
| + | |- | ||
| + | | 44 || Isolated Mitochondrial Complex Deficiencies || || || style="font-style: italic; color: blue;" | | ||
| + | |- | ||
| + | | 45 || Disorders of Replication, Transcription and Translation of Mitochondrial DNA || || || style="font-style: italic; color: blue;" | | ||
| + | |- | ||
| + | | 46 || Disorders of Mitochondrial Homeostatis, Dynamics, Protein Import, and Quality Control || || || style="font-style: italic; color: blue;" | | ||
|- | |- | ||
| 47 || Primary CoQ10 deficiencies || [https://www.wikipathways.org/index.php/Pathway:WP5037 WP5037] || 16|| style="font-style: italic; color: blue;" | Approved | | 47 || Primary CoQ10 deficiencies || [https://www.wikipathways.org/index.php/Pathway:WP5037 WP5037] || 16|| style="font-style: italic; color: blue;" | Approved | ||
|- | |- | ||
| 48 || Disorders of carnitine, fatty acid and fatty aldehyde metabolism || [https://www.wikipathways.org/index.php/Pathway:WP5123 WP5123] || 17 || style="font-style: italic; color: orange;" | In Progress | | 48 || Disorders of carnitine, fatty acid and fatty aldehyde metabolism || [https://www.wikipathways.org/index.php/Pathway:WP5123 WP5123] || 17 || style="font-style: italic; color: orange;" | In Progress | ||
| + | |- | ||
| + | | 49 || Disorders of Glycerol Metabolism || || || style="font-style: italic; color: blue;" | | ||
|- | |- | ||
| 50 || Disorders of ketone body metabolism || Fig.23.1 and 23.2:[https://www.wikipathways.org/index.php/Pathway:WP5175 WP5175], <br/> Fig.23.3: [https://www.wikipathways.org/index.php/Pathway:WP5195 WP5195] || 23|| style="font-style: italic; color: blue;" | Approved | | 50 || Disorders of ketone body metabolism || Fig.23.1 and 23.2:[https://www.wikipathways.org/index.php/Pathway:WP5175 WP5175], <br/> Fig.23.3: [https://www.wikipathways.org/index.php/Pathway:WP5195 WP5195] || 23|| style="font-style: italic; color: blue;" | Approved | ||
| + | |- | ||
| + | | 51 || Disorders of Complex Lipids || || || style="font-style: italic; color: blue;" | | ||
|- | |- | ||
| 52 || Disorders of eicosanoid metabolism (including leukotrienes) || [https://www.wikipathways.org/index.php/Pathway:WP5171 WP5171] || 38|| style="font-style: italic; color: blue;" | Approved | | 52 || Disorders of eicosanoid metabolism (including leukotrienes) || [https://www.wikipathways.org/index.php/Pathway:WP5171 WP5171] || 38|| style="font-style: italic; color: blue;" | Approved | ||
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|- | |- | ||
| 57 || Disorders of Heme metabolism || [https://www.wikipathways.org/index.php/Pathway:WP5169 WP5169] || 33 || style="font-style: italic; color: blue;" | Approved | | 57 || Disorders of Heme metabolism || [https://www.wikipathways.org/index.php/Pathway:WP5169 WP5169] || 33 || style="font-style: italic; color: blue;" | Approved | ||
| + | |- | ||
| + | | 58 || Inherited Disorders of Bilirubin Metabolite || || || style="font-style: italic; color: blue;" | | ||
| + | |- | ||
| + | | 59 || Disorders of Autophagy || || || style="font-style: italic; color: blue;" | | ||
|- | |- | ||
| 60 || Lysosomal storage disorders || [https://www.wikipathways.org/index.php/Pathway:WP4153 WP4153] || 25|| style="font-style: italic; color: blue;" | Approved (ed.5) || 8, 8 unconnected | | 60 || Lysosomal storage disorders || [https://www.wikipathways.org/index.php/Pathway:WP4153 WP4153] || 25|| style="font-style: italic; color: blue;" | Approved (ed.5) || 8, 8 unconnected | ||
| + | |- | ||
| + | | 61 || The Neuronal Ceroid Lipofuscinoses || || || || no pathway diagram | ||
| + | |- | ||
| + | | 62 || Mucolipidoses, Multiple Sulfatase Deficiency, and Cathepsin K and C Deficiency || || || style="font-style: italic; color: blue;" | | ||
| + | |- | ||
| + | | 63 || Oligosaccharidoses and Sialic Acid Disorders || || || style="font-style: italic; color: blue;" | | ||
| + | |- | ||
| + | | 64 || The Mucopolysaccharidoses || || || style="font-style: italic; color: blue;" | | ||
|- | |- | ||
| 65 || Disorders of oxalate metabolism || [https://www.wikipathways.org/index.php/Pathway:WP5166 WP5166] || 28 || style="font-style: italic; color: blue;" | Approved | | 65 || Disorders of oxalate metabolism || [https://www.wikipathways.org/index.php/Pathway:WP5166 WP5166] || 28 || style="font-style: italic; color: blue;" | Approved | ||
|- | |- | ||
| 66 || Congenital disorders of N-linked and O-linked glycosylation || [https://www.wikipathways.org/index.php/Pathway:WP4521 WP4521] || 30|| style="font-style: italic; color: blue;" | Approved | | 66 || Congenital disorders of N-linked and O-linked glycosylation || [https://www.wikipathways.org/index.php/Pathway:WP4521 WP4521] || 30|| style="font-style: italic; color: blue;" | Approved | ||
| + | |- | ||
| + | | 67 || Disorders of Oxalate Metabolism || || || style="font-style: italic; color: blue;" | | ||
| + | |- | ||
| + | | 68 || Congenital Disorders of Glycosylation || || || style="font-style: italic; color: blue;" | | ||
|- | |- | ||
| 69 || Cerebral organic acidurias || [https://www.wikipathways.org/index.php/Pathway:WP4519 WP4519] and [https://www.wikipathways.org/index.php/Pathway:WP5030 WP5030] || 8 & 9|| style="font-style: italic; color: blue;" | Approved | | 69 || Cerebral organic acidurias || [https://www.wikipathways.org/index.php/Pathway:WP4519 WP4519] and [https://www.wikipathways.org/index.php/Pathway:WP5030 WP5030] || 8 & 9|| style="font-style: italic; color: blue;" | Approved | ||
| + | |- | ||
| + | | 70 || 3-Methylglutaconic Acidurias || || || style="font-style: italic; color: blue;" | | ||
|- | |- | ||
| - || Disorders of phosphoinositide metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4971 WP4971] || NA || style="font-style: italic; color: blue;" | Approved | | - || Disorders of phosphoinositide metabolism || [https://www.wikipathways.org/index.php/Pathway:WP4971 WP4971] || NA || style="font-style: italic; color: blue;" | Approved | ||
Current revision
| Chapter ed. 5 | Title | Links WP | Chapter ed. 4 | Status | Diseases: x from ch. ed. 4 (+y) from other ch. |
|---|---|---|---|---|---|
| 13 | Disorders of pyrimidine and purine metabolism | WP4225 and WP4224 | 41 | Approved (ed.5) | |
| 14 | Disorders of Nucleotide Metabolism | ||||
| 15 | Creatine disorders | WP5190 | 32 | Approved | |
| 16 | Disorders of glutathione metabolism | WP4518 | 42 | Approved | |
| 17 | Disorders of ammonia detoxification | WP4595 | 4 | Approved | |
| 18 | Disorders of amino acid transport | WP5029 | 6 | Approved | |
| 19 | Disorders of monoamine metabolism | WP4220 | 31 | Approved (ed.5) | 6, non missing |
| 20 | Disorders of phenylalanine and tetrahydrobiopterin metabolism | WP4156 | 1 | Approved (ed.5) | 8 (+2), non missing |
| 21 | Disorders of tyrosine metabolism | WP4506 | 2 | Approved (ed.5) | 5, non missing |
| 22 | Disorders of sulfur amino acid and sulfide metabolism | WP4292 | 3 | Approved | 7, non missing |
| 23 | Disorders of branched-chain amino acid metabolism | WP4686 | 7 | Approved | |
| 24 | Disorders of Beta and Gamma Amino Acids | Fig.24.2: WP4157 | 5 (Fig.5.3) | Approved (ed.5) | 2, non missing |
| 26 | Disorders of glycine metabolism | Fig.5.1:WP5028, Fig.5.4: WP5026 | 5 | In Progress | |
| 26 | Disorders of glycine metabolism | Fig.5.2: WP4688 | 5 | Approved | |
| 27 | Disorders of Lipoic Acid and Iron-Sulphur Protein Metabolism | ||||
| 28 | Disorders of cobalamin metabolism | WP4271 | 13 | Approved | |
| 29 | Disorders of folate metabolism | WP4259 and WP4288 | 10 | Approved | 9 (+3), non missing |
| 30 | Disorders of biotin metabolism | WP5031 | 14 | Approved | |
| 31 | Disorders of thiamine metabolism | WP4297 | 15 | Approved | |
| 32 | Disorders of riboflavin metabolism | WP5037 | 16 | Approved | |
| 33 | Disorders of Niacin, NAD, and Pantothenate Metabolism | ||||
| 34 | Vitamin B6 -Dependent and Responsive Disorders | WP4228 | 11 | Approved (ed.5) | 5, non missing |
| 35 | Disorders of molybdenum metabolism | WP4507 and WP4504 | 12 | Approved | |
| 36 | Disorders of copper , zinc and selenium metabolism | WP5189 | 39 | Approved | |
| 37 | Iron metabolism disorder | WP5172 | 40 | Approved | |
| 38 | Disorders of Manganese Metabolism | ||||
| 39 | Disorders of carbohydrate and glucose transport | Fig.18.3:WP5173, Fig.18.4: WP5178 | 18 | Approved | |
| 40 | Disorders of Pentose Phosphate Pathway and Polyol Metabolism | ||||
| 41 | Disorders Congenital Hyperinsulinism | ||||
| 42 | Disorders of pyruvate and Krebs cycle metabolism | WP4236 | 20 | Approved | |
| 43 | Disorders of Mitochondrial Carriers | ||||
| 44 | Isolated Mitochondrial Complex Deficiencies | ||||
| 45 | Disorders of Replication, Transcription and Translation of Mitochondrial DNA | ||||
| 46 | Disorders of Mitochondrial Homeostatis, Dynamics, Protein Import, and Quality Control | ||||
| 47 | Primary CoQ10 deficiencies | WP5037 | 16 | Approved | |
| 48 | Disorders of carnitine, fatty acid and fatty aldehyde metabolism | WP5123 | 17 | In Progress | |
| 49 | Disorders of Glycerol Metabolism | ||||
| 50 | Disorders of ketone body metabolism | Fig.23.1 and 23.2:WP5175, Fig.23.3: WP5195 | 23 | Approved | |
| 51 | Disorders of Complex Lipids | ||||
| 52 | Disorders of eicosanoid metabolism (including leukotrienes) | WP5171 | 38 | Approved | |
| 53 | Disorders of lipoprotein metabolism | WP4522 | 43 | Approved | |
| 54 | Cholesterol synthesis disorders | WP5193 | 36 | Approved | |
| 55 | Disorders of steroid metabolism | WP4523 and WP4524 | 37 | Approved | |
| 56 | Disorders of Bile acid synthesis (and biliary transport) | WP5176 | 34 | Approved | |
| 57 | Disorders of Heme metabolism | WP5169 | 33 | Approved | |
| 58 | Inherited Disorders of Bilirubin Metabolite | ||||
| 59 | Disorders of Autophagy | ||||
| 60 | Lysosomal storage disorders | WP4153 | 25 | Approved (ed.5) | 8, 8 unconnected |
| 61 | The Neuronal Ceroid Lipofuscinoses | no pathway diagram | |||
| 62 | Mucolipidoses, Multiple Sulfatase Deficiency, and Cathepsin K and C Deficiency | ||||
| 63 | Oligosaccharidoses and Sialic Acid Disorders | ||||
| 64 | The Mucopolysaccharidoses | ||||
| 65 | Disorders of oxalate metabolism | WP5166 | 28 | Approved | |
| 66 | Congenital disorders of N-linked and O-linked glycosylation | WP4521 | 30 | Approved | |
| 67 | Disorders of Oxalate Metabolism | ||||
| 68 | Congenital Disorders of Glycosylation | ||||
| 69 | Cerebral organic acidurias | WP4519 and WP5030 | 8 & 9 | Approved | |
| 70 | 3-Methylglutaconic Acidurias | ||||
| - | Disorders of phosphoinositide metabolism | WP4971 | NA | Approved | |
| - | Oxysterols derived from cholesterol | WP4545 | NA | Approved | |
| - | Mitochondrial oxidative phosphorylation | 22 | In Progress |
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