Dual hijack model of Vif in HIV infection (Homo sapiens)
From WikiPathways
Description
By hijacking CBF-b, Vif (Viral infectivity factor, HIV protein) is manipulating the ubquitination machinery and adversely effecting host transcriptional regulation.
This pathways was adapted from figure 3 in Fraser et al.
Quality Tags
Ontology Terms
Bibliography
- Fraser JS, Gross JD, Krogan NJ; ''From systems to structure: bridging networks and mechanism.''; Mol Cell, 2013 PubMed Europe PMC Scholia
History
View all... |
External references
DataNodes
View all... |
Name | Type | Database reference | Comment |
---|---|---|---|
A3G | GeneProduct | ENSG00000239713 (Ensembl) | |
CBFB | GeneProduct | ENSG00000067955 (Ensembl) | |
CUL5 | GeneProduct | ENSG00000166266 (Ensembl) | |
E2 | GeneProduct | ENSG00000067955 (Ensembl) | |
ELOB | GeneProduct | ENSG00000103363 (Ensembl) | |
ELOC | GeneProduct | ENSG00000154582 (Ensembl) | |
RBX1 | GeneProduct | ENSG00000100387 (Ensembl) | |
RUNX1 | GeneProduct | ENSG00000159216 (Ensembl) | |
UBB | GeneProduct | ENSG00000170315 (Ensembl) | |
Vif | GeneProduct |
Annotated Interactions
No annotated interactions