NOTCH1 regulation of endothelial cell calcification (Homo sapiens)

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1Flow / Shear stressValve endotheliumInterstitial CellExtracellular MatrixSAT1VEGFMGPALPLSOX6CALUGJA5NOTCH1FGFR3PAR1ITGA1Secreted proteinsPLATCalcificationPTHrPDLL1DLL3DLL4JAG1JAG2


Description

Model of NOTCH1 regulation of human endothelial cell calcification. This pathway is part the CPTAC Assay Portal.

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Ontology Terms

 

Bibliography

  1. White MP, Theodoris CV, Liu L, Collins WJ, Blue KW, Lee JH, Meng X, Robbins RC, Ivey KN, Srivastava D; ''NOTCH1 regulates matrix gla protein and calcificationgene networks in human valve endothelium.''; J Mol Cell Cardiol, 2015 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
116601view09:29, 9 May 2021EweitzModified title
106657view21:17, 12 September 2019KhanspersModified description
105658view05:15, 10 August 2019KhanspersModified description
87953view13:07, 25 July 2016ElisaOntology Term : 'regulatory pathway' added !
87385view11:05, 22 July 2016MaintBotadded missing graphids
82217view20:45, 15 September 2015Khanspersupdates
81814view06:06, 1 September 2015KhanspersModified description
81813view06:04, 1 September 2015KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ALPLGeneProductENSG00000162551 (Ensembl)
CALUGeneProductENSG00000128595 (Ensembl)
DLL1GeneProductENSG00000198719 (Ensembl)
DLL3GeneProductENSG00000090932 (Ensembl)
DLL4GeneProductENSG00000128917 (Ensembl)
FGFR3GeneProductENSG00000068078 (Ensembl)
GJA5GeneProduct2702 (Entrez Gene)
ITGA1GeneProductENSG00000213949 (Ensembl)
JAG1GeneProductENSG00000101384 (Ensembl)
JAG2GeneProductENSG00000184916 (Ensembl)
MGPProteinENSG00000111341 (Ensembl)
NOTCH1GeneProductENSG00000148400 (Ensembl)
PAR1GeneProductENSG00000198121 (Ensembl)
PLATProteinENSG00000104368 (Ensembl)
PTHrPProteinENSG00000104368 (Ensembl)
SAT1GeneProductENSG00000130066 (Ensembl)
SOX6GeneProductENSG00000110693 (Ensembl)
VEGFGeneProductENSG00000112715 (Ensembl)

Annotated Interactions

No annotated interactions

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