STING pathway in Kawasaki-like disease and COVID-19 (Homo sapiens)

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Viral DNAIVIgFCGR2AVitamin D3ATP2B2Aspirinangiotensin IIcalciumDNA polymerase IIIPOLR2EPOLR3GLPOLR3FPOLR3GPOLR3HPOLR2KPOLR2HPOLR3EcGAMPPOLR3KPOLR2FPOLR2LPOLR3APOLR1CPOLR3CPOLR3DPOLR3BPOLR1DTBK1IKBKENLRX1MAVSSTING1TRADDFADDRIPK1CASP8CASP10IRF3IRF7IRF3IRF7Type I interferonsIFNA10IFNA8IFNA16IFNA2IFNA7IFNA21IFNA17IFNA14IFNA4IFNA1IFNA13IFNA5IFNA6IFNB1CGAScalcium


Description

STING pathway relevant to KAwasaki-like disease in COVID-19

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Quality Tags

Ontology Terms

 

Bibliography

  1. Berthelot JM, Drouet L, Lioté F; ''Kawasaki-like diseases and thrombotic coagulopathy in COVID-19: delayed over-activation of the STING pathway?''; Emerg Microbes Infect, 2020 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
129327view14:05, 26 March 2024MkutmonOntology Term : 'disease pathway' added !
123345view09:50, 17 July 2022EgonwAdded two more identifiers
120610view02:18, 18 December 2021EweitzRefine graphics
120609view00:17, 18 December 2021EweitzTighten graphics, refine case
118842view09:21, 2 June 2021EweitzOntology Term : 'COVID-19' added !
118841view09:21, 2 June 2021EweitzOntology Term : 'DOID:934' removed !
115144view18:43, 28 January 2021Khanspersupdated node to label
114103view18:35, 22 December 2020EgonwA class of gene products
114102view18:29, 22 December 2020EgonwConverted Labels to DataNodes
114038view17:53, 17 December 2020EgonwReplaced a ChEBI ID of a dizwitterion with the uncharged alternative with a Wikidata mapping.
113917view03:07, 9 December 2020KhanspersOntology Term : 'viral infectious disease' added !
113916view03:06, 9 December 2020KhanspersOntology Term : 'pattern recognition receptor mediated signaling pathway' added !
113915view22:23, 8 December 2020KhanspersOntology Term : 'Kawasaki disease' added !
113914view22:07, 8 December 2020KhanspersModified description
113913view22:02, 8 December 2020Khanspersadded F3 gene, removed calcium
113825view08:26, 30 November 2020FehrhartModified description
113665view22:48, 10 November 2020KhanspersWork on progress
113664view21:46, 10 November 2020Khansperswork in progress
111341view22:21, 28 July 2020Khansperswork in progress
111340view21:55, 28 July 2020KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATP2B2GeneProductENSG00000157087 (Ensembl)
AspirinMetaboliteCHEBI:15365 (ChEBI)
CASP10GeneProductENSG00000003400 (Ensembl)
CASP8GeneProductENSG00000064012 (Ensembl)
CGASGeneProductENSG00000164430 (Ensembl)
FADDGeneProductENSG00000168040 (Ensembl)
FCGR2AGeneProductENSG00000143226 (Ensembl)
IFNA10GeneProduct3446 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA13GeneProduct3447 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA1GeneProduct3439 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA14GeneProduct3448 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA16GeneProduct3449 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA17GeneProduct3451 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA21GeneProduct3452 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA2GeneProduct3440 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA4GeneProduct3441 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA5GeneProduct3442 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA6GeneProduct3443 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA7GeneProduct3444 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA8GeneProduct3445 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNB1GeneProduct3456 (Entrez Gene) Original kegg element: gene;1;hsa:3456
IKBKEGeneProductENSG00000263528 (Ensembl)
IRF3GeneProductENSG00000126456 (Ensembl)
IRF7GeneProductENSG00000185507 (Ensembl)
MAVSGeneProductENSG00000088888 (Ensembl)
NLRX1GeneProductENSG00000160703 (Ensembl)
POLR1CGeneProductENSG00000171453 (Ensembl)
POLR1DGeneProductENSG00000186184 (Ensembl)
POLR2EGeneProductENSG00000099817 (Ensembl)
POLR2FGeneProductENSG00000100142 (Ensembl)
POLR2HGeneProductENSG00000163882 (Ensembl)
POLR2KGeneProductENSG00000147669 (Ensembl)
POLR2LGeneProductENSG00000177700 (Ensembl)
POLR3AGeneProductENSG00000148606 (Ensembl)
POLR3BGeneProductENSG00000013503 (Ensembl)
POLR3CGeneProductENSG00000186141 (Ensembl)
POLR3DGeneProductENSG00000168495 (Ensembl)
POLR3EGeneProductENSG00000058600 (Ensembl)
POLR3FGeneProductENSG00000132664 (Ensembl)
POLR3GGeneProductENSG00000113356 (Ensembl)
POLR3GLGeneProductENSG00000121851 (Ensembl)
POLR3HGeneProductENSG00000100413 (Ensembl)
POLR3KGeneProductENSG00000161980 (Ensembl)
RIPK1GeneProductENSG00000137275 (Ensembl)
STING1GeneProductENSG00000184584 (Ensembl)
TBK1GeneProductENSG00000183735 (Ensembl)
TRADDGeneProductENSG00000102871 (Ensembl)
Vitamin D3MetaboliteCHEBI:28940 (ChEBI)
angiotensin IIMetaboliteCHEBI:58506 (ChEBI)
cGAMPMetaboliteCHEBI:71580 (ChEBI)
calciumMetaboliteCHEBI:22984 (ChEBI)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP4961"
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