Hepatocyte growth factor receptor signaling (Bos taurus)
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DeSl
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Trancription
AKT Pathway
Transcription
of Cox2
Cytoplasm
RAC1
pathway
Changes in Cytoskeleton
and Cell mobility
Actin
Right Click for Comments
AP-1
Extracellular
Transcription
Anoikis
RHO
pathway
CDC42
pathway
P
P
P
FOS
PTPN11
ELK1
MAP4K1
PXN
MAPK1
PIK3CA
PAK1
GRB2
PXN
MAPK8
C-MET
PTK2B
JUN
SRC
RAP1B
CRKL
GAB1
SRC
HRAS
STAT3
CRK
PTEN
MAP2K2
RAF1
PTK2
RAPGEF1
RASA1
MAPK3
RAP1A
MAP2K1
ITGB1
PTK2
DOCK1
HGF
PTK2B
ITGA1
SOS1
Description
No description
Comments
GenMAPP remarks
Converted to human by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP313(79946)
with a 100.0% conversion rate.
Try the New WikiPathways
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Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
Organ SL, Tsao MS; ''An overview of the c-MET signaling pathway.''; Ther Adv Med Oncol, 2011
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
118734
view
10:48, 1 June 2021
DeSl
Converted 2 lines to GraphicalLine
118733
view
10:47, 1 June 2021
DeSl
Added states iso textlabel P
118732
view
10:46, 1 June 2021
DeSl
Converted ReceptorSquare to MIMbinding with lit ref
118731
view
10:43, 1 June 2021
DeSl
Added description from WP313
117607
view
11:38, 21 May 2021
Eweitz
Modified title
80800
view
15:26, 30 June 2015
Mkutmon
homology conversion
63315
view
21:05, 9 May 2013
MaintBot
Updated to 2013 gpml schema
40496
view
19:28, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33740
view
23:55, 8 December 2009
MaintBot
Automatic update of empty xrefs
32511
view
12:52, 17 August 2009
MaintBot
Fixed text labels
32199
view
12:37, 15 August 2009
MaintBot
Fixed text labels
31681
view
11:44, 14 August 2009
MaintBot
Fixed group labels
31209
view
19:36, 13 August 2009
MaintBot
Fixed text labels
30615
view
22:20, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
C-MET
GeneProduct
ENSBTAG00000006161 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4233
CRK
GeneProduct
ENSBTAG00000005665 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1398
CRKL
GeneProduct
ENSBTAG00000045548 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1399
DOCK1
GeneProduct
ENSBTAG00000031890 (Ensembl)
Interim Symbol: Dock1 predicted and Name: dedicator of cyto-kinesis 1 (predicted)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1793
ELK1
GeneProduct
ENSBTAG00000015817 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2002
FOS
GeneProduct
ENSBTAG00000004322 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2353
GAB1
GeneProduct
ENSBTAG00000002813 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2549
GRB2
GeneProduct
ENSBTAG00000004736 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2885
HGF
GeneProduct
ENSBTAG00000017664 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3082
HRAS
GeneProduct
ENSBTAG00000046644 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3265
ITGA1
GeneProduct
ENSBTAG00000016525 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3672
ITGB1
GeneProduct
ENSBTAG00000015910 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3688
JUN
GeneProduct
ENSBTAG00000004037 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3725
MAP2K1
GeneProduct
ENSBTAG00000033983 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5604
MAP2K2
GeneProduct
ENSBTAG00000024450 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5605
MAP4K1
GeneProduct
ENSBTAG00000021145 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:11184
MAPK1
GeneProduct
ENSBTAG00000010312 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5594
MAPK3
GeneProduct
ENSBTAG00000016156 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5595
MAPK8
GeneProduct
ENSBTAG00000007876 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5599
PAK1
GeneProduct
ENSBTAG00000010191 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5058
PIK3CA
GeneProduct
ENSBTAG00000009232 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5290
PTEN
GeneProduct
ENSBTAG00000009498 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5728
PTK2B
GeneProduct
ENSBTAG00000005958 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2185
PTK2
GeneProduct
ENSBTAG00000009578 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5747
PTPN11
GeneProduct
ENSBTAG00000002048 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5781
PXN
GeneProduct
ENSBTAG00000018108 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5829
RAF1
GeneProduct
ENSBTAG00000045748 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5894
RAP1A
GeneProduct
ENSBTAG00000014710 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5906
RAP1B
GeneProduct
ENSBTAG00000008967 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5908
RAPGEF1
GeneProduct
ENSBTAG00000020791 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2889
RASA1
GeneProduct
ENSBTAG00000009565 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5921
SOS1
GeneProduct
ENSBTAG00000011643 (Ensembl)
Son of sevenless homolog 1 (Drosophila) (predicted)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6654
SRC
GeneProduct
ENSBTAG00000008938 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6714
STAT3
GeneProduct
ENSBTAG00000021523 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6774
Annotated Interactions
No annotated interactions
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