Fatty acid biosynthesis (Caenorhabditis elegans)
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1
TCA Cycle
Long-Chain fatty acid
Palmitoyl-ACP
Acyl-CoA (n+2)
6 iterations
Crotonoyl-ACP
Acetyl-synthase
Fatty acyl CoA
Mitochondrion
Cytosol
Triacylglyceride Synthesis
Malonyl-ACP
less than 6 iterations
Acetyl-ACP
Butyryl-ACP
Acetoacetyl-ACP
pyruvate
ACSL5
F54C8.1
ACACB
acs-17
Thiolases
F32H2.5
Palmitate
W09H1.5
3-L-Hydroxyacyl-CoA
oxaloacetate
ACACA
F53C11.3
F32H2.5
F32H2.5
F37C12.7
PECR
F32H2.5
C32E8.9
fat-5
Acetyl-CoA
F32H2.5
beta-hydroxybutyryl
C36A4.9
3-ketoacyl-CoA
ECHDC2
F32H2.5
Malonyl-CoA
D1005.1
trans-delta2-enoyl-CoA
F32H2.5
ACSL6
ech-2
Y25C1A.13
pyc-1
Y65B4BL.5
ech-6
citrate
F32H2.5
Description
No description
Comments
GenMAPP notes
Updated from Kam Dahlquists original by Magali Jaillard, Marijke Vermeer, Michiel Adrieans, Ron Schormans and Chris Evelo
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Quality Tags
Ontology Terms
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Bibliography
Watts JL; ''Fat synthesis and adiposityregulation in Caenorhabditis elegans.''; Trends Endocrinol Metab, 2009
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
125346
view
19:40, 3 February 2023
AlexanderPico
removed old genmapp comments
118560
view
11:57, 28 May 2021
DeSl
Modified description
118559
view
11:54, 28 May 2021
DeSl
Reconnected some proteins
118558
view
11:53, 28 May 2021
DeSl
Added lit. ref., cleaned up comments in description
118557
view
11:51, 28 May 2021
DeSl
Added PW DataNode IDs, converted textlabels to metabolites
118450
view
14:54, 27 May 2021
Fehrhart
connected line, added metabolite identifiers and proper catalysis and anchors
118126
view
10:33, 25 May 2021
Eweitz
Modified title
109400
view
16:44, 16 March 2020
L Dupuis
Fixed interactions
73759
view
00:09, 22 February 2014
MaintBot
updating schema
67240
view
10:25, 26 June 2013
Christine Chichester
Ontology Term : 'fatty acid biosynthetic pathway' added !
53642
view
10:54, 10 November 2012
Egonw
Connected more dots
53592
view
20:58, 9 November 2012
Egonw
Connecting dots...
53591
view
20:56, 9 November 2012
Egonw
Replaced multiple general nodes by Metabolite DataNode's.
40643
view
19:58, 1 March 2011
MaintBot
Removed redundant pathway information and comments
20757
view
11:29, 14 November 2008
MaintBot
[[Pathway:Caenorhabditis elegans:Fatty Acid Synthesis BiGCaT]] moved to [[Pathway:WP38]]: Moved to stable identifier
8564
view
14:03, 7 January 2008
MaintBot
Added to category $category
19458
view
14:03, 7 January 2008
Evelo
Uploaded new pathway
8562
view
14:03, 7 January 2008
Kdahlquist
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
3-L-Hydroxyacyl-CoA
Metabolite
3-ketoacyl-CoA
Metabolite
CHEBI:57347 (ChEBI)
ACACA
GeneProduct
ACACB
GeneProduct
ACSL5
GeneProduct
ACSL6
GeneProduct
Acetoacetyl-ACP
Metabolite
Acetyl-ACP
Metabolite
Acetyl-CoA
Metabolite
HMDB01206 (HMDB)
Acetyl-synthase
Metabolite
Acyl-CoA (n+2)
Metabolite
Butyryl-ACP
Metabolite
C32E8.9
GeneProduct
171951 (Entrez Gene)
C36A4.9
GeneProduct
175500 (Entrez Gene)
Crotonoyl-ACP
Metabolite
D1005.1
GeneProduct
180485 (Entrez Gene)
ECHDC2
GeneProduct
F32H2.5
GeneProduct
172715 (Entrez Gene)
F37C12.7
GeneProduct
176005 (Entrez Gene)
F53C11.3
GeneProduct
179872 (Entrez Gene)
F54C8.1
GeneProduct
186222 (Entrez Gene)
Fatty acyl CoA
Metabolite
Long-Chain fatty acid
Metabolite
Malonyl-ACP
Metabolite
Malonyl-CoA
Metabolite
HMDB01175 (HMDB)
PECR
GeneProduct
Palmitate
Metabolite
CHEBI:15756 (ChEBI)
Palmitoyl-ACP
Metabolite
TCA Cycle
Pathway
WP76 (WikiPathways)
Thiolases
GeneProduct
176756 (Entrez Gene)
Triacylglyceride Synthesis
Pathway
WP212 (WikiPathways)
W09H1.5
GeneProduct
174963 (Entrez Gene)
Y25C1A.13
GeneProduct
173657 (Entrez Gene)
Y65B4BL.5
GeneProduct
171643 (Entrez Gene)
acs-17
GeneProduct
180859 (Entrez Gene)
beta-hydroxybutyryl
Metabolite
citrate
Metabolite
CHEBI:133748 (ChEBI)
ech-2
GeneProduct
3564942 (Entrez Gene)
ech-6
GeneProduct
176376 (Entrez Gene)
fat-5
GeneProduct
180162 (Entrez Gene)
oxaloacetate
Metabolite
CHEBI:16452 (ChEBI)
pyc-1
GeneProduct
179616 (Entrez Gene)
pyruvate
Metabolite
CHEBI:15361 (ChEBI)
trans-delta2-enoyl-CoA
Metabolite
Annotated Interactions
No annotated interactions
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DataNodes
Annotated Interactions
No annotated interactions