Mitochondrial long chain fatty acid beta-oxidation (Caenorhabditis elegans)

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12,4 Dienoyl-CoALong chain Acyl-CoAAcetyl-CoATrans-Δ²-Enoyl-CoACis-Δ³-Enoyl-CoAcytosolLong chain acyl-carnitinesaturatedAcyl-CoA (n-2)Long Chain Fatty AcidLong chain acyl-carnitineunsaturatedmitochondrial matrixAcyl-CoA dehydrogenases:Long chain Acyl-CoA3-Ketoacyl-CoA3-L-Hydroxyacyl-CoAT08B2.7Y57A10C.6PECRDCIcpt-2F37C12.7E04F6.5dif-1acs-17cpt-1EHHADHACADLT08G2.3Y65B4BL.5ACADSACSL2F54C8.1cytosolmitochondrial matrix


Description

Mitochondrial fatty acid β-oxidation (FAO) is crucial in the prodcution of energy, especially during fasting and metabolic stress. Fatty acids (FAs) are oxidized through 4 reaction mechanisms, and this pathway describes the mitochondrial beta-oxidation of dietary long chain fatty acids.

Comments

GenMAPP notes 
mitochondrial beta-oxidation of dietary long chain fatty acids
GenMAPP remarks 
Adapted from GenMAPP

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Quality Tags

Ontology Terms

 

Bibliography

  1. Elle IC, Rødkær SV, Fredens J, Færgeman NJ; ''A method for measuring fatty acid oxidation in C. elegans.''; Worm, 2012 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118575view12:26, 28 May 2021DeSlAdded two IDs for lipids
118574view12:24, 28 May 2021DeSlUpdated description
118572view12:23, 28 May 2021DeSlModified description
118571view12:20, 28 May 2021DeSlRemoved last modified item.
118570view12:20, 28 May 2021DeSlAdded lit ref
118569view12:19, 28 May 2021DeSlReconnected all proteins
118443view14:46, 27 May 2021ZiskaChanged D to Δ
118437view14:43, 27 May 2021ZiskaConnected lines, changed text labels into metabolites
118178view10:47, 25 May 2021EweitzModified title
71437view19:05, 17 October 2013MaintBotAutomated update of data sources
68479view20:44, 5 July 2013MaintBotUpdated to 2013 gpml schema
67483view11:07, 26 June 2013DdiglesOntology Term : 'fatty acid beta degradation pathway' added !
40632view19:57, 1 March 2011MaintBotRemoved redundant pathway information and comments
21622view11:32, 14 November 2008MaintBot[[Pathway:Caenorhabditis elegans:Mitochondrial fatty acid betaoxidation]] moved to [[Pathway:WP448]]: Moved to stable identifier
8573view14:03, 7 January 2008MaintBotAdded to category $category
8571view14:03, 7 January 2008N.ReyesUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
2,4 Dienoyl-CoAMetabolite
3-Ketoacyl-CoAMetabolite
3-L-Hydroxyacyl-CoAMetabolite
ACADLGeneProduct
ACADSGeneProduct
ACSL2GeneProduct
Acetyl-CoAMetabolite
Acyl-CoA (n-2)Metabolite
Cis-Δ³-Enoyl-CoAMetabolite
DCIGeneProduct
E04F6.5GeneProduct174180 (Entrez Gene)
EHHADHGeneProduct
F37C12.7GeneProduct176005 (Entrez Gene)
F54C8.1GeneProduct186222 (Entrez Gene)
Long Chain Fatty AcidMetabolite
Long chain Acyl-CoAMetabolite
Long chain acyl-carnitineMetabolite
PECRGeneProduct
T08B2.7GeneProduct172310 (Entrez Gene) similiar to: ECHA_RAT
T08G2.3GeneProduct181757 (Entrez Gene)
Trans-Δ²-Enoyl-CoAMetabolite
Y57A10C.6GeneProduct174881 (Entrez Gene)
Y65B4BL.5GeneProduct171643 (Entrez Gene)
acs-17GeneProduct180859 (Entrez Gene)
cpt-1GeneProduct174912 (Entrez Gene)
cpt-2GeneProduct178025 (Entrez Gene)
dif-1GeneProduct177530 (Entrez Gene)

Annotated Interactions

No annotated interactions
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