Phosphoinositides metabolism (Homo sapiens)
From WikiPathways
Description
Signaling pathway of Resolvin for resolution of inflammation in Polymorphonuclear Neutrophils and Acinar Cells.
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Ontology Terms
Bibliography
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- Laporte J, Hu LJ, Kretz C, Mandel JL, Kioschis P, Coy JF, Klauck SM, Poustka A, Dahl N; ''A gene mutated in X-linked myotubular myopathy definesa new putative tyrosine phosphatase family conserved in yeast.''; Nat Genet, 1996 PubMed Europe PMC Scholia
- Ungewickell A, Hugge C, Kisseleva M, Chang SC, Zou J, Feng Y, Galyov EE, Wilson M, Majerus PW; ''''; , PubMed Europe PMC Scholia
- Rameh LE, Tolias KF, Duckworth BC, Cantley LC; ''A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate.''; Nature, 1997 PubMed Europe PMC Scholia
- Rohrschneider LR, Fuller JF, Wolf I, Liu Y, Lucas DM; ''Structure, function, and biology of SHIP proteins.''; Genes Dev, 2000 PubMed Europe PMC Scholia
- Li S, Tiab L, Jiao X, Munier FL, Zografos L, Frueh BE, Sergeev Y, Smith J, Rubin B, Meallet MA, Forster RK, Hejtmancik JF, Schorderet DF; ''Mutations in PIP5K3 are associated with François-Neetens mouchetée fleck corneal dystrophy.''; Am J Hum Genet, 2005 PubMed Europe PMC Scholia
- Bolino A, Muglia M, Conforti FL, LeGuern E, Salih MA, Georgiou DM, Christodoulou K, Hausmanowa-Petrusewicz I, Mandich P, Schenone A, Gambardella A, Bono F, Quattrone A, Devoto M, Monaco AP; ''Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2.''; Nat Genet, 2000 PubMed Europe PMC Scholia
- Rusten TE, Stenmark H; ''Analyzing phosphoinositides and their interacting proteins.''; Nat Methods, 2006 PubMed Europe PMC Scholia
- Malek M, Kielkowska A, Chessa T, Anderson KE, Barneda D, Pir P, Nakanishi H, Eguchi S, Koizumi A, Sasaki J, Juvin V, Kiselev VY, Niewczas I, Gray A, Valayer A, Spensberger D, Imbert M, Felisbino S, Habuchi T, Beinke S, Cosulich S, Le Novère N, Sasaki T, Clark J, Hawkins PT, Stephens LR; ''PTEN Regulates PI(3,4)P2Signaling Downstream of Class I PI3K.''; Mol Cell, 2017 PubMed Europe PMC Scholia
- Poli A, Zaurito AE, Abdul-Hamid S, Fiume R, Faenza I, Divecha N; ''Phosphatidylinositol 5 Phosphate (PI5P): From Behind the Scenes to the Front (Nuclear) Stage.''; Int J Mol Sci, 2019 PubMed Europe PMC Scholia
- Backer JM; ''The regulation and function of Class III PI3Ks:novel roles for Vps34.''; Biochem J, 2008 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
ADCY1 | Protein | ENSG00000164742 (Uniprot-TrEMBL) | |
AKT1 | GeneProduct | ENSG00000142208 (Ensembl) | |
ATP | Metabolite | CHEBI:30616 (ChEBI) | |
CMKLR1 | GeneProduct | ENSG00000174600 (Ensembl) | |
FPR2 | GeneProduct | ENSG00000171049 (Ensembl) | |
GRK1 | Protein | Q15835 (Uniprot-TrEMBL) | |
LTB4 | Metabolite | CHEBI:15647 (ChEBI) | |
LTB4R | GeneProduct | ENSG00000213903 (Ensembl) | |
MAPK1 | Protein | P28482 (Uniprot-TrEMBL) | |
MTORC2 | GeneProduct | MTOR (HGNC) | |
NFkB | Pathway | WP4562 (WikiPathways) | |
PDK1 | GeneProduct | ENSG00000152256 (Ensembl) | |
PI-3 kinase I | Protein | 2.7.1.137 (Enzyme Nomenclature) | |
PIK3CA | Protein | P42336 (Uniprot-TrEMBL) | |
PIK3CB | Protein | P42338 (Uniprot-TrEMBL) | |
PIK3CD | Protein | O00329 (Uniprot-TrEMBL) | |
PIK3CG | Protein | P48736 (Uniprot-TrEMBL) | |
RvD1 | Metabolite | CHEBI:81564 (ChEBI) | |
RvE1 | Metabolite | CHEBI:81559 (ChEBI) | |
TNF-α signaling | Pathway | WP231 (WikiPathways) | |
cAMP | Metabolite | CHEBI:17489 (ChEBI) |
Annotated Interactions
No annotated interactions