The production of fatty acids from acetyl-CoA and NADPH through the use of enzymes known as fatty acid synthases is referred to as fatty acid synthesis. This biological process occurs within the cytoplasm of cells. The majority of acetyl-CoA that is transformed into fatty acids originates from carbohydrates through the glycolytic pathway.
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Updated from original (Kam Dahlquist) by Magali Jaillard, Marijke Vermeer, Michiel Adrieans, Ron Schormans and Chris Evelo
de Renobales M, Blomquist GJ; ''Biosynthesis of medium chain fatty acids in Drosophila melanogaster.''; Arch Biochem Biophys, 1984 PubMedEurope PMCScholia
Keith AD; ''Fatty acid metabolism in Drosophila melanogaster: interaction between dietary fatty acids and de novo synthesis.''; Comp Biochem Physiol, 1967 PubMedEurope PMCScholia
Parvy JP, Napal L, Rubin T, Poidevin M, Perrin L, Wicker-Thomas C, Montagne J; ''Drosophila melanogaster Acetyl-CoA-carboxylase sustains a fatty acid-dependent remote signal to waterproof the respiratory system.''; PLoS Genet, 2012 PubMedEurope PMCScholia
Lowe PN, Rhodes S; ''Purification and characterization of [acyl-carrier-protein] acetyltransferase from Escherichia coli.''; Biochem J, 1988 PubMedEurope PMCScholia
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