Wnt/Beta-catenin signaling inhibitors in current and past clinical trials (Homo sapiens)

Revision as of 08:54, 7 February 2024 by Andra (Talk | contribs)

Description

Wnt/β-catenin signaling inhibitors in current and past clinical trials

View approved pathways at the new wikipathways.org.

Jung YS, Park JI; ''Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex.''; Exp Mol Med, 2020 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
134411	view	20:48, 21 July 2024	Eweitz	Fix organelle z-index, standardize case, economize layout
128747	view	07:45, 21 February 2024	Egonw	Added a missing Wikidata identifier
128746	view	07:38, 21 February 2024	Egonw	Replaced an replaced Wikidata identifier
128745	view	07:35, 21 February 2024	Egonw	Updated the Ensembl data sources
128744	view	06:51, 21 February 2024	Egonw	Updated the UniProt data source
128652	view	21:07, 17 February 2024	AlexanderPico	Added phosphorylation of LRP6
128651	view	21:03, 17 February 2024	AlexanderPico	added LRP5/6; fixed interactions; economized layout
128650	view	20:40, 17 February 2024	AlexanderPico	fixed WNT, labelled Ac, removed states; will add LRP5/6 and new states
128649	view	20:26, 17 February 2024	AlexanderPico	Ontology Term : 'Wnt signaling pathway' added !
128648	view	20:26, 17 February 2024	AlexanderPico	Ontology Term : 'signaling pathway' added !
128493	view	08:54, 7 February 2024	Andra	Completed the pathways as depicted in https://www.nature.com/articles/s41392-022-01042-7
128492	view	07:43, 7 February 2024	Andra	New pathway

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Name	Type	Database reference
CGX-1321	Metabolite	Q124448546 (Wikidata)
ETC-1922159	Metabolite	Q124448578 (Wikidata)
PORCN	GeneProduct	ENSG00000102312 (Ensembl Human)
RXC004	Metabolite	Q124439695 (Wikidata)
WINT	GeneProduct	IPR005817 (InterPro)
WNT-974	Metabolite	46926973 (PubChem-compound)

No annotated interactions