Sulfur amino acid biosynthesis (Saccharomyces cerevisiae)

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H2OSO42-oxobutanoateNH3tetrahydropteroyltri-L-glutamateO-acetyl-L-homoserineSO3S-adenosyl-L-methionineAPSPAPSNH3H2OH2OH2SpyruvateH2OO-acetyl-L-homoserine3 H2O5-methyltetrahydropteroyltri-L-glutamate3 NADPCYS4ATPMET16STR2homocysteineCYS3SAM2adenosine-3',5'-bisphosphateSTR3Coenzyme AphosphateMET3pyrophosphateADP3 NADPHcystathionineATPMET2MET10acetateNADPHMET14L-serinepyrophosphateacetateacetyl-CoAATPMET17SAM1homoserineECM17L-methionineL-cysteineMET6


Description

The synthesis of methionine and cysteine (among other sulfur-containing compounds) from sulfate, ATP, NADPH, and serine.

Comments

 
Based on http://pathway.yeastgenome.org/biocyc/

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Quality Tags

Ontology Terms

 

Bibliography

  1. Thomas D, Surdin-Kerjan Y; ''Metabolism of sulfur amino acids in Saccharomyces cerevisiae.''; Microbiol Mol Biol Rev, 1997 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
134130view10:40, 30 June 2024EgonwAdded a relevant paper
134129view10:39, 30 June 2024EgonwRemoved a broken link
134128view10:38, 30 June 2024EgonwUnbolded some labels
125063view23:14, 17 January 2023AlexanderPicoModified description
124904view07:35, 31 December 2022EgonwMachine readable interactions
117342view11:51, 20 May 2021EweitzModified title
92811view19:23, 8 July 2017AlexanderPicoRemoved old genmapp tags and unused attributes
92795view15:29, 6 July 2017DeSlQuick edit to datanode annotation or property
89657view04:56, 24 September 2016EgonwReplace the CAS number of the salt with that of just the metabolite.
89648view16:00, 23 September 2016EgonwReplace the CAS number of the salt with that of just the metabolite.
70252view21:38, 15 July 2013MaintBotupdated to 2013 schema
67667view11:46, 26 June 2013DdiglesOntology Term : 'cysteine and methionine metabolic pathway' added !
53535view19:39, 8 November 2012EgonwMarked several DataNode's as Metabolite.
46439view01:47, 28 January 2012Khanspersremoved problematic characters in labels
41918view04:54, 2 March 2011MaintBotRemoved redundant pathway information and comments
20687view11:29, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:Sulfur Amino Acid Biosynthesis]] moved to [[Pathway:WP7]]: Moved to stable identifier
12855view08:05, 17 May 2008MaintBotautomated metabolite conversion
8939view14:12, 7 January 2008MaintBotAdded to category $category
8937view14:12, 7 January 2008J.HeckmanUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
2-oxobutanoateMetabolite
3 H2OMetabolite
3 NADPMetabolite
3 NADPHMetabolite53-57-6 (CAS)
5-methyltetrahydropteroyltri-L-glutamateMetabolite
ADPMetabolite58-64-0 (CAS)
APSMetabolite
ATPMetabolite1927-31-7 (CAS)
CYS3GeneProductS000000010 (SGD)
CYS4GeneProductS000003387 (SGD)
Coenzyme AMetabolite64885-97-8 (CAS)
ECM17GeneProductS000003898 (SGD)
H2OMetabolite
H2SMetabolite
L-cysteineMetabolite52-90-4 (CAS)
L-methionineMetabolite63-68-3 (CAS)
L-serineMetabolite56-45-1 (CAS)
MET10GeneProductS000001926 (SGD)
MET14GeneProductS000001484 (SGD)
MET16GeneProductS000006371 (SGD)
MET17GeneProductS000004294 (SGD)
MET2GeneProductS000005221 (SGD)
MET3GeneProductS000003771 (SGD)
MET6GeneProductS000000893 (SGD) 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
NADPHMetabolite53-57-6 (CAS)
NH3Metabolite
O-acetyl-L-homoserineMetabolite
PAPSMetabolite
S-adenosyl-L-methionineMetabolite
SAM1GeneProductS000004170 (SGD)
SAM2GeneProductS000002910 (SGD)
SO3Metabolite
SO4Metabolite
STR2GeneProductS000003891 (SGD)
STR3GeneProductS000003152 (SGD)
acetateMetabolite64-19-7 (CAS)
acetyl-CoAMetabolite72-89-9 (CAS)
adenosine-3',5'-bisphosphateMetabolite3805-37-6 (CAS)
cystathionineMetabolite535-34-2 (CAS)
homocysteineMetabolite6027-13-0 (CAS)
homoserineMetabolite672-15-1 (CAS)
phosphateMetabolite14265-44-2 (CAS)
pyrophosphateMetabolite2466-09-3 (CAS)
pyruvateMetabolite
tetrahydropteroyltri-L-glutamateMetabolite

Annotated Interactions

No annotated interactions
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