Hepatocyte growth factor receptor signaling (Gallus gallus)
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P
RAC1
pathway
P
CDC42
pathway
Extracellular
AKT Pathway
P
Anoikis
Right Click for Comments
Cytoplasm
Actin
Transcription
of Cox2
Transcription
AP-1
Changes in Cytoskeleton
and Cell mobility
Trancription
RHO
pathway
MAP2K2
RAF1
RAPGEF1
PXN
RASA1
SOS1
CRKL
RAP1B
PIK3CA
PTEN
MAPK1
MAPK3
RAP1A
DOCK1
Met
ELK1
MAPK8
JUN
GRB2
PTK2
PTPN11
ITGB1
GAB1
MAP4K1
SRC
HGF
PTK2B
HRAS
STAT3
PXN
PAK1
FOS
MAP2K1
PTK2
PTK2B
CRK
SRC
ITGA1
Description
No description
Comments
GenMAPP remarks
Converted to human by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP313(r21339)
with a 78% conversion rate.
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Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
Organ SL, Tsao MS; ''An overview of the c-MET signaling pathway.''; Ther Adv Med Oncol, 2011
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
118803
view
07:47, 2 June 2021
DeSl
Converted "P" textlabels to states
118802
view
07:46, 2 June 2021
DeSl
Converted ReceptorSquare to MIM binding with lit. ref.
118801
view
07:44, 2 June 2021
DeSl
Removed textLabel
118800
view
07:44, 2 June 2021
DeSl
Ontology Term : 'hepatocyte' added !
118799
view
07:43, 2 June 2021
DeSl
Ontology Term : 'Rho/Rac/Cdc42 mediated signaling pathway' added !
118798
view
07:43, 2 June 2021
DeSl
Added description from WP313
118039
view
11:50, 23 May 2021
Eweitz
Modified title
109466
view
10:53, 18 March 2020
L Dupuis
Converted interaction lines representing membrane to graphical lines
87669
view
08:55, 25 July 2016
Lindarieswijk
Ontology Term : 'scatter factor/hepatocyte growth factor signaling pathway' added !
68877
view
17:22, 8 July 2013
MaintBot
Updated to 2013 gpml schema
41018
view
22:57, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33939
view
18:13, 9 December 2009
MaintBot
Automatic update of empty xrefs
33484
view
15:08, 30 November 2009
MaintBot
Removed group label
31534
view
21:45, 13 August 2009
MaintBot
Fixed text labels
30379
view
21:02, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
CRK
GeneProduct
417553 (Entrez Gene)
CRKL
GeneProduct
416939 (Entrez Gene)
DOCK1
GeneProduct
423960 (Entrez Gene)
Interim Symbol: Dock1 predicted and Name: dedicator of cyto-kinesis 1 (predicted)
ELK1
GeneProduct
FOS
GeneProduct
GAB1
GeneProduct
422456 (Entrez Gene)
GRB2
GeneProduct
386572 (Entrez Gene)
HGF
GeneProduct
395941 (Entrez Gene)
HRAS
GeneProduct
396229 (Entrez Gene)
ITGA1
GeneProduct
395951 (Entrez Gene)
ITGB1
GeneProduct
374058 (Entrez Gene)
JUN
GeneProduct
424673 (Entrez Gene)
MAP2K1
GeneProduct
415549 (Entrez Gene)
MAP2K2
GeneProduct
396349 (Entrez Gene)
MAP4K1
GeneProduct
MAPK1
GeneProduct
373953 (Entrez Gene)
MAPK3
GeneProduct
MAPK8
GeneProduct
423778 (Entrez Gene)
Met
GeneProduct
PAK1
GeneProduct
419083 (Entrez Gene)
PIK3CA
GeneProduct
424971 (Entrez Gene)
PTEN
GeneProduct
423675 (Entrez Gene)
PTK2
GeneProduct
396416 (Entrez Gene)
PTK2B
GeneProduct
PTPN11
GeneProduct
395815 (Entrez Gene)
PXN
GeneProduct
395832 (Entrez Gene)
RAF1
GeneProduct
396245 (Entrez Gene)
RAP1A
GeneProduct
419867 (Entrez Gene)
RAP1B
GeneProduct
417840 (Entrez Gene)
RAPGEF1
GeneProduct
417173 (Entrez Gene)
RASA1
GeneProduct
427327 (Entrez Gene)
SOS1
GeneProduct
Son of sevenless homolog 1 (Drosophila) (predicted)
SRC
GeneProduct
396442 (Entrez Gene)
STAT3
GeneProduct
420027 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Discussion
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
Annotated Interactions
No annotated interactions