Glycolysis and gluconeogenesis (Mycobacterium tuberculosis)

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Carbon fixation in photosynthetic organismsPentose phosphate pathwayPyruvate metabolismPropanoate metabolismCitrate cycle (TCA cycle)Starch and sucrose metabolismko:K01222 ko:K01223pdhAArbutin 6-phosphatepfkBgpmAko:K03738ko:K02777 ko:K02752 ko:K02753PhosphoenolpyruvatetpiAaldehyde dehydrogenase (EC:1.2.1.3)acsArbutinppgK3-Phospho-D-glyceroyl phosphate2,3-Bisphospho-D-glyceratepgmAko:K01610sugar kinase (EC:2.7.-.-)Salicingpm2cpd:C05345fba[Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysinepfkAoxidoreductaselpdAaldC3-Phospho-D-glycerateko:K00169 ko:K00170 ko:K00172 ko:K00171ko:K02777 ko:K02778 ko:K02779 ko:K02790 ko:K02791adhko:K00150Pyruvateko:K02777 ko:K02749 ko:K02750 ko:K02752 ko:K02753ko:K00131aceEko:K00844Acetateko:K00114ko:K01905Salicin 6-phosphateko:K00844ko:K01222 ko:K01223adhE1ko:K01837adhAko:K01222 ko:K01223ko:K02777 ko:K02749 ko:K02750 ko:K02752 ko:K02753gapGlycerone phosphatedehydrogenaseko:K02777 ko:K02778 ko:K02779 ko:K02790 ko:K02791cpd:C00221ppgKaceEcpd:C00668Enzyme N6-(dihydrolipoyl)lysineko:K000162-Phospho-D-glycerateko:K02777 ko:K02778 ko:K02779 ko:K02790 ko:K02791ko:K02777 ko:K02752 ko:K02753Enzyme N6-(lipoyl)lysineko:K00129ko:K00169 ko:K00170 ko:K00172 ko:K00171ko:K02777 ko:K02749 ko:K02750 ko:K02752 ko:K02753ko:K01222 ko:K01223pdhAko:K00169 ko:K00170 ko:K00172 ko:K00171glpXko:K01568ko:K05344manBko:K01085ko:K00169 ko:K00170 ko:K00172 ko:K00171ko:K113892-(alpha-Hydroxyethyl)thiamine diphosphatepdhBko:K01568pdhCD-Glyceraldehyde 3-phosphatepykAcpd:C05378dehydrogenasephosphoglycerate mutase (phosphoglyceromutase) (EC:5.4.2.1)AcetaldehydealdAko:K01084ko:K02777 ko:K02749 ko:K02750 ko:K02752 ko:K02753enoadhBko:K02777 ko:K02778 ko:K02779 ko:K02790 ko:K02791pgiThiamin diphosphatepckAcpd:C00267ko:K01785ko:K01837Oxaloacetateko:K02777 ko:K02749 ko:K02750 ko:K02752 ko:K02753lpd(S)-Lactatesugar kinase (EC:2.7.-.-)EthanolD-Glucose 1-phosphatepdhBD-Glucosealdehyde dehydrogenase (EC:1.2.1.-)ko:K02777 ko:K02752 ko:K02753pgiAcetyl-CoApgipgkko:K04022adhCcpd:C01172ko:K01792ko:K02777 ko:K02778 ko:K02779 ko:K02790 ko:K02791


Description

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Bibliography

  1. Ganapathy U, Marrero J, Calhoun S, Eoh H, de Carvalho LP, Rhee K, Ehrt S; ''Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis.''; Nat Commun, 2015 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
120958view10:42, 3 February 2022EgonwMade three pathways clickable
117426view10:46, 21 May 2021EweitzModified title
95496view13:14, 18 December 2017DeSlRemoved licence number
95495view13:13, 18 December 2017DeSlAdded specific literature reference.
95494view13:09, 18 December 2017DeSlModified description
95493view13:09, 18 December 2017DeSlConnected last unconnected line
95491view13:06, 18 December 2017DeSlRemoved KEGHG orthologs which were not present for this species, changed layout, annotated nodes with Enzyme nomenclature/NCBI protein ID where needed, changed layout.
71589view19:30, 17 October 2013MaintBotAutomated update of data sources
69504view20:12, 8 July 2013MaintBotUpdated to 2013 gpml schema
67314view10:35, 26 June 2013Christine ChichesterOntology Term : 'glycolysis/gluconeogenesis pathway' added !
41440view01:07, 2 March 2011MaintBotRemoved redundant pathway information and comments
39002view20:03, 25 September 2010AlexanderPico
39001view20:02, 25 September 2010AlexanderPico
39000view20:01, 25 September 2010AlexanderPicofixed pathway nodes and lines
38214view23:29, 26 August 2010KhanspersChanged xrefs - TubercuList
37740view19:00, 30 June 2010KhanspersModified description
37729view23:35, 28 June 2010KhanspersChanged labels
37698view22:36, 25 June 2010KhanspersModified categories
37696view22:32, 25 June 2010KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(S)-LactateMetaboliteC00186 (Kegg Compound)
2,3-Bisphospho-D-glycerateMetaboliteC01159 (Kegg Compound)
2-(alpha-Hydroxyethyl)thiamine diphosphateMetaboliteC05125 (Kegg Compound)
2-Phospho-D-glycerateMetaboliteC00631 (Kegg Compound)
3-Phospho-D-glycerateMetaboliteC00197 (Kegg Compound)
3-Phospho-D-glyceroyl phosphateMetaboliteC00236 (Kegg Compound)
AcetaldehydeMetaboliteC00084 (Kegg Compound)
AcetateMetaboliteC00033 (Kegg Compound)
Acetyl-CoAMetaboliteC00024 (Kegg Compound)
Arbutin 6-phosphateMetaboliteC06187 (Kegg Compound)
ArbutinMetaboliteC06186 (Kegg Compound)
D-Glucose 1-phosphateMetaboliteC00103 (Kegg Compound)
D-GlucoseMetaboliteC00031 (Kegg Compound)
D-Glyceraldehyde 3-phosphateMetaboliteC00118 (Kegg Compound)
Enzyme N6-(dihydrolipoyl)lysineMetaboliteC15973 (Kegg Compound)
Enzyme N6-(lipoyl)lysineMetaboliteC15972 (Kegg Compound)
EthanolMetaboliteC00469 (Kegg Compound)
Glycerone phosphateMetaboliteC00111 (Kegg Compound)
OxaloacetateMetaboliteC00036 (Kegg Compound)
PhosphoenolpyruvateMetaboliteC00074 (Kegg Compound)
PyruvateMetaboliteC00022 (Kegg Compound)
Salicin 6-phosphateMetaboliteC06188 (Kegg Compound)
SalicinMetaboliteC01451 (Kegg Compound)
Thiamin diphosphateMetaboliteC00068 (Kegg Compound)
[Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysineMetaboliteC16255 (Kegg Compound)
aceEGeneProductRv2241 (Entrez Gene) Original kegg element: gene;13;mtu:Rv0843 mtu:Rv2241 mtu:Rv2496c mtu:Rv2497c
acsGeneProductRv3667 (Entrez Gene) Original kegg element: gene;91;mtu:Rv3667
adhAGeneProductRv1862 (Entrez Gene) Original kegg element: gene;10;mtu:Rv0162c mtu:Rv0761c mtu:Rv1530 mtu:Rv1862
adhBGeneProductRv0761c (Entrez Gene) Original kegg element: gene;10;mtu:Rv0162c mtu:Rv0761c mtu:Rv1530 mtu:Rv1862
adhCGeneProductRv3045 (Entrez Gene) Original kegg element: gene;9;mtu:Rv3045
adhE1GeneProductRv0162c (Entrez Gene) Original kegg element: gene;10;mtu:Rv0162c mtu:Rv0761c mtu:Rv1530 mtu:Rv1862
adhGeneProductRv1530 (Entrez Gene) Original kegg element: gene;10;mtu:Rv0162c mtu:Rv0761c mtu:Rv1530 mtu:Rv1862
aldAGeneProductRv0768 (Entrez Gene) Original kegg element: gene;2;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
aldCGeneProductRv2858c (Entrez Gene) Original kegg element: gene;2;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
aldehyde dehydrogenase (EC:1.2.1.-)GeneProductRv0147 (Entrez Gene) Original kegg element: gene;2;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
aldehyde dehydrogenase (EC:1.2.1.3)GeneProductRv0458 (Entrez Gene) Original kegg element: gene;2;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
cpd:C00221MetaboliteC00221 (Kegg Compound)
cpd:C00267MetaboliteC00267 (Kegg Compound)
cpd:C00668MetaboliteC00668 (Kegg Compound)
cpd:C01172MetaboliteC01172 (Kegg Compound)
cpd:C05345MetaboliteC05345 (Kegg Compound)
cpd:C05378MetaboliteC05378 (Kegg Compound)
dehydrogenaseGeneProductRv0843 (Entrez Gene) Original kegg element: gene;13;mtu:Rv0843 mtu:Rv2241 mtu:Rv2496c mtu:Rv2497c
enoGeneProductRv1023 (Entrez Gene) Original kegg element: gene;19;mtu:Rv1023
fbaGeneProductRv0363c (Entrez Gene) Original kegg element: gene;1;mtu:Rv0363c
gapGeneProductRv1436 (Entrez Gene) Original kegg element: gene;21;mtu:Rv1436
glpXGeneProductRv1099c (Entrez Gene) Original kegg element: gene;25;mtu:Rv1099c
gpm2GeneProductRv3214 (Entrez Gene) Original kegg element: gene;20;mtu:Rv0489 mtu:Rv2419c mtu:Rv3214
gpmAGeneProductRv0489 (Entrez Gene) Original kegg element: gene;20;mtu:Rv0489 mtu:Rv2419c mtu:Rv3214
ko:K00016GeneProductK00016 (Kegg ortholog)
ko:K00114GeneProductK00114 (Kegg ortholog)
ko:K00129GeneProductK00129 (Kegg ortholog)
ko:K00131GeneProductK00131 (Kegg ortholog)
ko:K00150GeneProductK00150 (Kegg ortholog)
ko:K00169 ko:K00170 ko:K00172 ko:K00171GeneProductK00169... (Kegg ortholog)
ko:K00844GeneProductK00844 (Kegg ortholog)
ko:K01084GeneProductK01084 (Kegg ortholog)
ko:K01085GeneProductK01085 (Kegg ortholog)
ko:K01222 ko:K01223GeneProductK01222... (Kegg ortholog)
ko:K01568GeneProductK01568 (Kegg ortholog)
ko:K01610GeneProductK01610 (Kegg ortholog)
ko:K01785GeneProductK01785 (Kegg ortholog)
ko:K01792GeneProductK01792 (Kegg ortholog)
ko:K01837GeneProductK01837 (Kegg ortholog)
ko:K01905GeneProductK01905 (Kegg ortholog)
ko:K02777 ko:K02749 ko:K02750 ko:K02752 ko:K02753GeneProductK02777... (Kegg ortholog)
ko:K02777 ko:K02752 ko:K02753GeneProductK02777... (Kegg ortholog)
ko:K02777 ko:K02778 ko:K02779 ko:K02790 ko:K02791GeneProductK02777... (Kegg ortholog)
ko:K03738GeneProductK03738 (Kegg ortholog)
ko:K04022GeneProductK04022 (Kegg ortholog)
ko:K05344GeneProductK05344 (Kegg ortholog)
ko:K11389GeneProductK11389 (Kegg ortholog)
lpdAGeneProductRv3303c (Entrez Gene) Original kegg element: gene;41;mtu:Rv0462 mtu:Rv0794c mtu:Rv3303c
lpdGeneProductRv0462 (Entrez Gene) Original kegg element: gene;41;mtu:Rv0462 mtu:Rv0794c mtu:Rv3303c
manBGeneProductRv3257c (Entrez Gene) Original kegg element: gene;28;mtu:Rv3068c mtu:Rv3257c
oxidoreductaseGeneProductRv0794c (Entrez Gene) Original kegg element: gene;41;mtu:Rv0462 mtu:Rv0794c mtu:Rv3303c
pckAGeneProductRv0211 (Entrez Gene) Original kegg element: gene;76;mtu:Rv0211
pdhAGeneProductRv2497c (Entrez Gene) Original kegg element: gene;13;mtu:Rv0843 mtu:Rv2241 mtu:Rv2496c mtu:Rv2497c
pdhBGeneProductRv2496c (Entrez Gene) Original kegg element: gene;13;mtu:Rv0843 mtu:Rv2241 mtu:Rv2496c mtu:Rv2497c
pdhCGeneProductRv2495c (Entrez Gene) Original kegg element: gene;14;mtu:Rv2495c
pfkAGeneProductRv3010c (Entrez Gene) Original kegg element: gene;24;mtu:Rv2029c mtu:Rv3010c
pfkBGeneProductRv2029c (Entrez Gene) Original kegg element: gene;24;mtu:Rv2029c mtu:Rv3010c
pgiGeneProductRv0946c (Entrez Gene) Original kegg element: gene;32;mtu:Rv0946c
pgkGeneProductRv1437 (Entrez Gene) Original kegg element: gene;42;mtu:Rv1437
pgmAGeneProductRv3068c (Entrez Gene) Original kegg element: gene;28;mtu:Rv3068c mtu:Rv3257c
phosphoglycerate mutase (phosphoglyceromutase) (EC:5.4.2.1)GeneProductRv2419c (Entrez Gene) Original kegg element: gene;20;mtu:Rv0489 mtu:Rv2419c mtu:Rv3214
ppgKGeneProductRv2702 (Entrez Gene) Original kegg element: gene;44;mtu:Rv2702
pykAGeneProductRv1617 (Entrez Gene) Original kegg element: gene;17;mtu:Rv1617
sugar kinase (EC:2.7.-.-)GeneProductRv0650 (Entrez Gene) Original kegg element: gene;35;mtu:Rv0650
tpiAGeneProductRv1438 (Entrez Gene) Original kegg element: gene;23;mtu:Rv1438

Annotated Interactions

No annotated interactions

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