Oxidative stress response (Canis familiaris)

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Immediate-earlygene inductionReactive Oxygen SpeciesInhibition of oxidasesTF inhibitionActivationInduction ofantioxidant genesStress-regulated MAP kinaseRepressionAdaptive responseRepression of ROS-producing systemsTF activationCATSOD1CYP1A1SOD2FOSSOD3Nrf2SP1TXNRD1MAOANFIXHMOX1JUNBTXN2MAPK10NQO1MT1XGCLCMAPK14UGT1A6GPX1GSRGSTT2GPX3CYBAMGST1NFKB1XDHTXNRD2


Description

No description

Comments

GenMAPP notes 
Adapted from Biochem J 1999 Sep 15;342 Pt 3:481-96 Morel Y, Barouki R. Repression of gene expression by oxidative stress. Biochem J 1999 Sep 15;342 Pt 3:481-96
GenMAPP remarks 
Adapted from rat by GenMAPP.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP408(r21540) with a 79% conversion rate.

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Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
117035view14:11, 16 May 2021EweitzModified title
88283view14:42, 1 August 2016FehrhartOntology Term : 'oxidative stress response pathway' added !
71466view19:17, 17 October 2013MaintBotAutomated update of data sources
68540view22:26, 5 July 2013MaintBotUpdated to 2013 gpml schema
40696view21:51, 1 March 2011MaintBotRemoved redundant pathway information and comments
33980view18:31, 9 December 2009MaintBotAutomatic update of empty xrefs
32258view12:59, 15 August 2009MaintBotFixed text labels
31780view12:11, 14 August 2009MaintBotFixed group labels
31283view20:03, 13 August 2009MaintBotFixed text labels
30735view23:01, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
CATGeneProduct403474 (Entrez Gene)
CYBAGeneProduct489664 (Entrez Gene) Probe set ID: u18729
CYP1A1GeneProduct487648 (Entrez Gene)
FOSGeneProduct490792 (Entrez Gene)
GCLCGeneProduct609822 (Entrez Gene)
GPX1GeneProduct442961 (Entrez Gene)
GPX3GeneProduct489179 (Entrez Gene)
GSRGeneProduct475596 (Entrez Gene)
GSTT2GeneProduct
HMOX1GeneProduct442987 (Entrez Gene)
JUNBGeneProduct484927 (Entrez Gene)
MAOAGeneProduct403450 (Entrez Gene)
MAPK10GeneProduct478464 (Entrez Gene)
MAPK14GeneProduct403856 (Entrez Gene)
MGST1GeneProduct477683 (Entrez Gene)
MT1XGeneProduct
NFIXGeneProduct484920 (Entrez Gene)
NFKB1GeneProduct442859 (Entrez Gene)
NQO1GeneProduct610935 (Entrez Gene)
Nrf2GeneProduct
SOD1GeneProduct403559 (Entrez Gene)
SOD2GeneProduct476258 (Entrez Gene)
SOD3GeneProduct488855 (Entrez Gene)
SP1GeneProduct486507 (Entrez Gene)
TXN2GeneProduct474519 (Entrez Gene)
TXNRD1GeneProduct474536 (Entrez Gene)
TXNRD2GeneProduct608155 (Entrez Gene)
UGT1A6GeneProduct403629 (Entrez Gene)
XDHGeneProduct483028 (Entrez Gene)

Annotated Interactions

No annotated interactions
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