Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)

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1-498, 99112145, 14623, 24637838-42138-1435011964120, 121147, 14898, 99104, 105147, 148127-1307771131, 13211881, 82125, 12619, 206, 75575127, 129, 133-13727-29145, 14657-5930-3721, 221076595-97539492, 93124113-1157414-1614711-131895, 100140, 14473108-11161, 625611951, 5283-91149, 150122, 12325, 2643-467217101, 102116, 1178-105, 66-706095, 100103547647-4910679, 8014, 151clathrin sculpted monoamine transport vesicle lumensynaptic vesicleGolgi lumenstored secretory granulelate endosome lumenendosome lumencytosolendoplasmic reticulum lumenMCT substratesNaDC3sodium ionD-fructosesodium ionH+Zinc 2+Noradrenaline uptake transporterSGLT4GLUT6/8/10/12NH4+sodium ionsodium ionGLUT7/11galactose, glucosecompounds transported by GLUT9GLUT9GLUT5RHAGsodium ionCholineURAT1CarnitineMagT1/2MTP1:Hephaestin (copper complex)sodium ionChlorideDopaminesodium ionsodium ionSuccinateInositolH+hexoses transported by GLUT7/11MATE1/2glycineH+sodium ionL-ProlineL-Prolineinorganic sulfatesodium ionSMITChlorideZn++sodium ionsodium ioniron (ferrous)DCT1hZIP5OAT2/4ErgothioneineOCT1H+sodium ioniron (3+)SMIT2ligands of SLC6A14OCT3 substratessodium ionSodium dependent Serotonin transporterCopperNaDC1ZIP6/ZIP14OCT2 substratesCholine2-Oxoglutaratealpha-D-glucosesodium ionsodium ionSOATNoradrenaline uptake transportersodium ionGlycineOCT3 substratesMagnesiumClass I GLUTsCTL1-5Carnitine transportersalpha-D-glucoseH+NH4+NaS2D-fructoseCholineChloridealpha-D-glucosehCTR1ligands of SLC6A12 (BGT-1)SLC6A15InositolGABAinorganic sulfateSLC6A GABA transportersgalactose, glucosehexoses transported by SGLT4Zn++UreaH+NRAMP1sodium ionZinc 2+sodium ionChloridesodium ionSolute carrier family 13 member 5H+MCT substratessodium ionsodium ioniron (3+)sodium ionDopamineSLC6A6Noradrenalinesodium ionNH4+NH4+Zn++hZIP1-4UreaH+RHCGsodium ioniron (ferrous)Divalent metals transported by NRAMP1MagnesiumH+CarnitineChlorideZnT2GABAligands of SLC6A15sodium ionOCT1 substratesSuccinatesodium ionZnT1MATE substratesligands of SLC6A6SGLT2ChlorideZnT3Urea transportersZnT5hexoses transported by GLUT7/11PROTH+OAT1-3SGLT1Biogenic amines transported by VMAT1/2ZnT6NH4+H+ligands of SLC6A15Zn++SerotoninH+ChlorideH+NaS1ligands of SLC6A6sodium ionligands of SLC6A19Citrateligands of SLC6A14OAT2/4 sulfate conjugate substratesProton myo-inositol cotransportersodium ionsodium ionNoradrenaline uptake transporterfructose, galactose, glucoseZIP8H+Inositols transported by SMIT2Inositols transported by SMIT2(S)-LactateBiogenic amines transported by VMAT1/2Divalent metals transported by NRAMP1H+sodium ion(S)-LactateSodium dpendent Dopamine transporterNH4+Noradrenalinesodium ionsodium ionUrateORCTL2 substratessodium ionOAT1-3 substratesInositolZn++H+ETTChlorideChlorideChlorideOCT2 substratesOAT1-3 substratesligands of SLC6A12 (BGT-1)sodium ionSLC6A19H+compounds transported by GLUT9sodium ionOCT1 substratessodium ionZnT8ORCTL2GLUT2 tetramertaurolithocholate sulfate5-HydroxytryptamineUratesodium ionRHBGORCTL2 substratessodium ionChloridetaurolithocholate sulfateZn++OCT3OAT2/4 sulfate conjugate substratesVMAT1/2H+H+ZnT7ligands of SLC6A19sodium ionsodium ionCitrateDicarboxylates transported by NaDC1hexoses transported by SGLT4CholineZn++H+Copperfructose, galactose, glucosesodium ionsodium ionInositolMonocarboxylate transportersGLYTsodium ionSLC6A20SLC6A18Ergothioneinesodium ionZIP7Dicarboxylates transported by NaDC1Chloridesodium ion2-oxoglutarateNAT1sodium ionMATE substratesChloridealpha-D-glucoseCHTSLC6A12SLC6A14MTP1:Ceruloplasmin (copper complex)hZIP10sodium ionChloride5


Description

Hexoses like glucose, galactose and fructose serve as basic fuel molecules for eukaryotic cells. Indeed, glucose is the main energy source for mammalian cells. These sugars are unable to diffuse across cellular membranes, and require transporter proteins for entry into and exit out of cells. Four gene families encode hexose transporter proteins (He et al, 2009). SLC2 family contains 14 genes and encode facilitative glucose transporters (GLUTs) (Uldry M and Thorens B, 2004). SLC5 family contains 12 genes and encode Na+/glucose symporters (Wright EM and Turk E, 2004). SLC37 family contains 4 members and encode sugar-phosphate/phosphate exchangers (Bartoloni L and Antonarakis SE, 2004). SLC45 family has 4 members and encode putative sugar/H+ symporters.

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  1. Hager K, Hazama A, Kwon HM, Loo DD, Handler JS, Wright EM.; ''Kinetics and specificity of the renal Na+/myo-inositol cotransporter expressed in Xenopus oocytes.''; PubMed Europe PMC Scholia
  2. Tandy S, Williams M, Leggett A, Lopez-Jimenez M, Dedes M, Ramesh B, Srai SK, Sharp P.; ''Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells.''; PubMed Europe PMC Scholia
  3. Lee A, Beck L, Markovich D.; ''The human renal sodium sulfate cotransporter (SLC13A1; hNaSi-1) cDNA and gene: organization, chromosomal localization, and functional characterization.''; PubMed Europe PMC Scholia
  4. Eraly SA, Nigam SK.; ''Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters.''; PubMed Europe PMC Scholia
  5. Quan H, Athirakul K, Wetsel WC, Torres GE, Stevens R, Chen YT, Coffman TM, Caron MG.; ''Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2.''; PubMed Europe PMC Scholia
  6. Merezhinskaya N, Fishbein WN, Davis JI, Foellmer JW.; ''Mutations in MCT1 cDNA in patients with symptomatic deficiency in lactate transport.''; PubMed Europe PMC Scholia
  7. Philp NJ, Wang D, Yoon H, Hjelmeland LM.; ''Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells.''; PubMed Europe PMC Scholia
  8. Kishi F, Nobumoto M.; ''Identification of natural resistance-associated macrophage protein in peripheral blood lymphocytes.''; PubMed Europe PMC Scholia
  9. Taylor KM, Morgan HE, Johnson A, Nicholson RI.; ''Structure-function analysis of HKE4, a member of the new LIV-1 subfamily of zinc transporters.''; PubMed Europe PMC Scholia
  10. Quadri M, Federico A, Zhao T, Breedveld GJ, Battisti C, Delnooz C, Severijnen LA, Di Toro Mammarella L, Mignarri A, Monti L, Sanna A, Lu P, Punzo F, Cossu G, Willemsen R, Rasi F, Oostra BA, van de Warrenburg BP, Bonifati V.; ''Mutations in SLC30A10 cause parkinsonism and dystonia with hypermanganesemia, polycythemia, and chronic liver disease.''; PubMed Europe PMC Scholia
  11. Taylor KM, Morgan HE, Johnson A, Hadley LJ, Nicholson RI.; ''Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters.''; PubMed Europe PMC Scholia
  12. Texel SJ, Xu X, Harris ZL.; ''Ceruloplasmin in neurodegenerative diseases.''; PubMed Europe PMC Scholia
  13. Palmiter RD, Cole TB, Quaife CJ, Findley SD.; ''ZnT-3, a putative transporter of zinc into synaptic vesicles.''; PubMed Europe PMC Scholia
  14. Loo DD, Eskandari S, Boorer KJ, Sarkar HK, Wright EM.; ''Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1.''; PubMed Europe PMC Scholia
  15. Erickson JD, Schafer MK, Bonner TI, Eiden LE, Weihe E.; ''Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter.''; PubMed Europe PMC Scholia
  16. Takanaga H, Mackenzie B, Suzuki Y, Hediger MA.; ''Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino.''; PubMed Europe PMC Scholia
  17. Chen H, Attieh ZK, Dang T, Huang G, van der Hee RM, Vulpe C.; ''Decreased hephaestin expression and activity leads to decreased iron efflux from differentiated Caco2 cells.''; PubMed Europe PMC Scholia
  18. Lin RY, Vera JC, Chaganti RS, Golde DW.; ''Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter.''; PubMed Europe PMC Scholia
  19. Kim KM, Kingsmore SF, Kingsmore SF, Han H, Yang-Feng TL, Godinot N, Seldin MF, Caron MG, Giros B.; ''Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes.''; PubMed Europe PMC Scholia
  20. O'Regan S, Traiffort E, Ruat M, Cha N, Compaore D, Meunier FM.; ''An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins.''; PubMed Europe PMC Scholia
  21. Taylor KM, Morgan HE, Johnson A, Nicholson RI.; ''Structure-function analysis of a novel member of the LIV-1 subfamily of zinc transporters, ZIP14.''; PubMed Europe PMC Scholia
  22. Rees MI, Harvey K, Pearce BR, Chung SK, Duguid IC, Thomas P, Beatty S, Graham GE, Armstrong L, Shiang R, Abbott KJ, Zuberi SM, Stephenson JB, Owen MJ, Tijssen MA, van den Maagdenberg AM, Smart TG, Supplisson S, Harvey RJ.; ''Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease.''; PubMed Europe PMC Scholia
  23. Liu Z, Chen Y, Mo R, Hui C, Cheng JF, Mohandas N, Huang CH.; ''Characterization of human RhCG and mouse Rhcg as novel nonerythroid Rh glycoprotein homologues predominantly expressed in kidney and testis.''; PubMed Europe PMC Scholia
  24. Geyer J, Döring B, Meerkamp K, Ugele B, Bakhiya N, Fernandes CF, Godoy JR, Glatt H, Petzinger E.; ''Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6).''; PubMed Europe PMC Scholia
  25. Gong S, Lu X, Xu Y, Swiderski CF, Jordan CT, Moscow JA.; ''Identification of OCT6 as a novel organic cation transporter preferentially expressed in hematopoietic cells and leukemias.''; PubMed Europe PMC Scholia
  26. Kleta R, Romeo E, Ristic Z, Ohura T, Stuart C, Arcos-Burgos M, Dave MH, Wagner CA, Camargo SR, Inoue S, Matsuura N, Helip-Wooley A, Bockenhauer D, Warth R, Bernardini I, Visser G, Eggermann T, Lee P, Chairoungdua A, Jutabha P, Babu E, Nilwarangkoon S, Anzai N, Kanai Y, Verrey F, Gahl WA, Koizumi A.; ''Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder.''; PubMed Europe PMC Scholia
  27. Erickson JD, Eiden LE.; ''Functional identification and molecular cloning of a human brain vesicle monoamine transporter.''; PubMed Europe PMC Scholia
  28. Kirschke CP, Huang L.; ''ZnT7, a novel mammalian zinc transporter, accumulates zinc in the Golgi apparatus.''; PubMed Europe PMC Scholia
  29. Race JE, Grassl SM, Williams WJ, Holtzman EJ.; ''Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3).''; PubMed Europe PMC Scholia
  30. Yoon H, Donoso LA, Philp NJ.; ''Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2.''; PubMed Europe PMC Scholia
  31. Pajor AM.; ''Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters.''; PubMed Europe PMC Scholia
  32. Otsuka M, Matsumoto T, Morimoto R, Arioka S, Omote H, Moriyama Y.; ''A human transporter protein that mediates the final excretion step for toxic organic cations.''; PubMed Europe PMC Scholia
  33. Schwienbacher C, Sabbioni S, Campi M, Veronese A, Bernardi G, Menegatti A, Hatada I, Mukai T, Ohashi H, Barbanti-Brodano G, Croce CM, Negrini M.; ''Transcriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples.''; PubMed Europe PMC Scholia
  34. Kambe T, Narita H, Yamaguchi-Iwai Y, Hirose J, Amano T, Sugiura N, Sasaki R, Mori K, Iwanaga T, Nagao M.; ''Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells.''; PubMed Europe PMC Scholia
  35. Apparsundaram S, Ferguson SM, George AL, Blakely RD.; ''Molecular cloning of a human, hemicholinium-3-sensitive choline transporter.''; PubMed Europe PMC Scholia
  36. Traiffort E, Ruat M, O'Regan S, Meunier FM.; ''Molecular characterization of the family of choline transporter-like proteins and their splice variants.''; PubMed Europe PMC Scholia
  37. Bressler JP, Olivi L, Cheong JH, Kim Y, Maerten A, Bannon D.; ''Metal transporters in intestine and brain: their involvement in metal-associated neurotoxicities.''; PubMed Europe PMC Scholia
  38. Tang NL, Ganapathy V, Wu X, Hui J, Seth P, Yuen PM, Wanders RJ, Fok TF, Hjelm NM.; ''Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency.''; PubMed Europe PMC Scholia
  39. Schneider S.; ''Inositol transport proteins.''; PubMed Europe PMC Scholia
  40. Ludewig U.; ''Electroneutral ammonium transport by basolateral rhesus B glycoprotein.''; PubMed Europe PMC Scholia
  41. Roll P, Massacrier A, Pereira S, Robaglia-Schlupp A, Cau P, Szepetowski P.; ''New human sodium/glucose cotransporter gene (KST1): identification, characterization, and mutation analysis in ICCA (infantile convulsions and choreoathetosis) and BFIC (benign familial infantile convulsions) families.''; PubMed Europe PMC Scholia
  42. Otonkoski T, Jiao H, Kaminen-Ahola N, Tapia-Paez I, Ullah MS, Parton LE, Schuit F, Quintens R, Sipilä I, Mayatepek E, Meissner T, Halestrap AP, Rutter GA, Kere J.; ''Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells.''; PubMed Europe PMC Scholia
  43. Borden LA, Dhar TG, Smith KE, Branchek TA, Gluchowski C, Weinshank RL.; ''Cloning of the human homologue of the GABA transporter GAT-3 and identification of a novel inhibitor with selectivity for this site.''; PubMed Europe PMC Scholia
  44. Lu R, Chan BS, Schuster VL.; ''Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C.''; PubMed Europe PMC Scholia
  45. Leyva-Illades D, Chen P, Zogzas CE, Hutchens S, Mercado JM, Swaim CD, Morrisett RA, Bowman AB, Aschner M, Mukhopadhyay S.; ''SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity.''; PubMed Europe PMC Scholia
  46. Girard JP, Baekkevold ES, Feliu J, Brandtzaeg P, Amalric F.; ''Molecular cloning and functional analysis of SUT-1, a sulfate transporter from human high endothelial venules.''; PubMed Europe PMC Scholia
  47. Christiansen B, Meinild AK, Jensen AA, Braüner-Osborne H.; ''Cloning and characterization of a functional human gamma-aminobutyric acid (GABA) transporter, human GAT-2.''; PubMed Europe PMC Scholia
  48. Westhoff CM, Ferreri-Jacobia M, Mak DO, Foskett JK.; ''Identification of the erythrocyte Rh blood group glycoprotein as a mammalian ammonium transporter.''; PubMed Europe PMC Scholia
  49. Wille S, Szekeres A, Majdic O, Prager E, Staffler G, Stöckl J, Kunthalert D, Prieschl EE, Baumruker T, Burtscher H, Zlabinger GJ, Knapp W, Stockinger H.; ''Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells.''; PubMed Europe PMC Scholia
  50. Kaler P, Prasad R.; ''Molecular cloning and functional characterization of novel zinc transporter rZip10 (Slc39a10) involved in zinc uptake across rat renal brush-border membrane.''; PubMed Europe PMC Scholia
  51. Masuda S, Terada T, Yonezawa A, Tanihara Y, Kishimoto K, Katsura T, Ogawa O, Inui K.; ''Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.''; PubMed Europe PMC Scholia
  52. Chimienti F, Favier A, Seve M.; ''ZnT-8, a pancreatic beta-cell-specific zinc transporter.''; PubMed Europe PMC Scholia
  53. Seow HF, Bröer S, Bröer A, Bailey CG, Potter SJ, Cavanaugh JA, Rasko JE.; ''Hartnup disorder is caused by mutations in the gene encoding the neutral amino acid transporter SLC6A19.''; PubMed Europe PMC Scholia
  54. Pacholczyk T, Blakely RD, Amara SG.; ''Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter.''; PubMed Europe PMC Scholia
  55. Chen NH, Reith ME, Quick MW.; ''Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6.''; PubMed Europe PMC Scholia
  56. Halestrap AP.; ''Monocarboxylic acid transport.''; PubMed Europe PMC Scholia
  57. Palmiter RD, Cole TB, Findley SD.; ''ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration.''; PubMed Europe PMC Scholia
  58. Hyland CA, Chérif-Zahar B, Cowley N, Raynal V, Parkes J, Saul A, Cartron JP.; ''A novel single missense mutation identified along the RH50 gene in a composite heterozygous Rhnull blood donor of the regulator type.''; PubMed Europe PMC Scholia
  59. Rasola A, Galietta LJ, Barone V, Romeo G, Bagnasco S.; ''Molecular cloning and functional characterization of a GABA/betaine transporter from human kidney.''; PubMed Europe PMC Scholia
  60. Berry GT, Mallee JJ, Kwon HM, Rim JS, Mulla WR, Muenke M, Spinner NB.; ''The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3): molecular cloning and localization to chromosome 21.''; PubMed Europe PMC Scholia
  61. Anderson CM, Ganapathy V, Thwaites DT.; ''Human solute carrier SLC6A14 is the beta-alanine carrier.''; PubMed Europe PMC Scholia
  62. Cha SH, Sekine T, Kusuhara H, Yu E, Kim JY, Kim DK, Sugiyama Y, Kanai Y, Endou H.; ''Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.''; PubMed Europe PMC Scholia
  63. Kagara N, Tanaka N, Noguchi S, Hirano T.; ''Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells.''; PubMed Europe PMC Scholia
  64. Wang H, Fei YJ, Kekuda R, Yang-Feng TL, Devoe LD, Leibach FH, Prasad PD, Ganapathy V.; ''Structure, function, and genomic organization of human Na(+)-dependent high-affinity dicarboxylate transporter.''; PubMed Europe PMC Scholia
  65. Wu X, Huang W, Ganapathy ME, Wang H, Kekuda R, Conway SJ, Leibach FH, Ganapathy V.; ''Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney.''; PubMed Europe PMC Scholia
  66. Sahni J, Nelson B, Scharenberg AM.; ''SLC41A2 encodes a plasma-membrane Mg2+ transporter.''; PubMed Europe PMC Scholia
  67. Ramamoorthy S, Leibach FH, Mahesh VB, Han H, Yang-Feng T, Blakely RD, Ganapathy V.; ''Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta.''; PubMed Europe PMC Scholia
  68. Takanaga H, Mackenzie B, Peng JB, Hediger MA.; ''Characterization of a branched-chain amino-acid transporter SBAT1 (SLC6A15) that is expressed in human brain.''; PubMed Europe PMC Scholia
  69. Tokuhiro S, Yamada R, Chang X, Suzuki A, Kochi Y, Sawada T, Suzuki M, Nagasaki M, Ohtsuki M, Ono M, Furukawa H, Nagashima M, Yoshino S, Mabuchi A, Sekine A, Saito S, Takahashi A, Tsunoda T, Nakamura Y, Yamamoto K.; ''An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.''; PubMed Europe PMC Scholia
  70. Garcia CK, Goldstein JL, Pathak RK, Anderson RG, Brown MS.; ''Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle.''; PubMed Europe PMC Scholia
  71. Ostlund RE, Seemayer R, Gupta S, Kimmel R, Ostlund EL, Sherman WR.; ''A stereospecific myo-inositol/D-chiro-inositol transporter in HepG2 liver cells. Identification with D-chiro-[3-3H]inositol.''; PubMed Europe PMC Scholia
  72. Zhang L, Schaner ME, Giacomini KM.; ''Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).''; PubMed Europe PMC Scholia
  73. Tuschl K, Clayton PT, Gospe SM, Gulab S, Ibrahim S, Singhi P, Aulakh R, Ribeiro RT, Barsottini OG, Zaki MS, Del Rosario ML, Dyack S, Price V, Rideout A, Gordon K, Wevers RA, Chong WK, Mills PB.; ''Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man.''; PubMed Europe PMC Scholia
  74. De Feo CJ, Aller SG, Unger VM.; ''A structural perspective on copper uptake in eukaryotes.''; PubMed Europe PMC Scholia
  75. Enomoto A, Wempe MF, Tsuchida H, Shin HJ, Cha SH, Anzai N, Goto A, Sakamoto A, Niwa T, Kanai Y, Anders MW, Endou H.; ''Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition.''; PubMed Europe PMC Scholia
  76. Höglund PJ, Adzic D, Scicluna SJ, Lindblom J, Fredriksson R.; ''The repertoire of solute carriers of family 6: identification of new human and rodent genes.''; PubMed Europe PMC Scholia
  77. Bakhiya A, Bahn A, Burckhardt G, Wolff N.; ''Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux.''; PubMed Europe PMC Scholia
  78. Uldry M, Ibberson M, Horisberger JD, Chatton JY, Riederer BM, Thorens B.; ''Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain.''; PubMed Europe PMC Scholia
  79. Gründemann D, Harlfinger S, Golz S, Geerts A, Lazar A, Berkels R, Jung N, Rubbert A, Schömig E.; ''Discovery of the ergothioneine transporter.''; PubMed Europe PMC Scholia
  80. Morrow JA, Collie IT, Dunbar DR, Walker GB, Shahid M, Hill DR.; ''Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome.''; PubMed Europe PMC Scholia
  81. Gorboulev V, Ulzheimer JC, Akhoundova A, Ulzheimer-Teuber I, Karbach U, Quester S, Baumann C, Lang F, Busch AE, Koepsell H.; ''Cloning and characterization of two human polyspecific organic cation transporters.''; PubMed Europe PMC Scholia
  82. Nair TS, Kozma KE, Hoefling NL, Kommareddi PK, Ueda Y, Gong TW, Lomax MI, Lansford CD, Telian SA, Satar B, Arts HA, El-Kashlan HK, Berryhill WE, Raphael Y, Carey TE.; ''Identification and characterization of choline transporter-like protein 2, an inner ear glycoprotein of 68 and 72 kDa that is the target of antibody-induced hearing loss.''; PubMed Europe PMC Scholia
  83. Canli T, Lesch KP.; ''Long story short: the serotonin transporter in emotion regulation and social cognition.''; PubMed Europe PMC Scholia
  84. Inoue K, Zhuang L, Ganapathy V.; ''Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function.''; PubMed Europe PMC Scholia
  85. Shafqat S, Velaz-Faircloth M, Henzi VA, Whitney KD, Yang-Feng TL, Seldin MF, Fremeau RT.; ''Human brain-specific L-proline transporter: molecular cloning, functional expression, and chromosomal localization of the gene in human and mouse genomes.''; PubMed Europe PMC Scholia
  86. Devergnas S, Chimienti F, Naud N, Pennequin A, Coquerel Y, Chantegrel J, Favier A, Seve M.; ''Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study.''; PubMed Europe PMC Scholia
  87. Gaither LA, Eide DJ.; ''Functional expression of the human hZIP2 zinc transporter.''; PubMed Europe PMC Scholia
  88. Reece M, Prawitt D, Landers J, Kast C, Gros P, Housman D, Zabel BU, Pelletier J.; ''Functional characterization of ORCTL2--an organic cation transporter expressed in the renal proximal tubules.''; PubMed Europe PMC Scholia
  89. Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Cha SH, Hosoyamada M, Takeda M, Sekine T, Igarashi T, Matsuo H, Kikuchi Y, Oda T, Ichida K, Hosoya T, Shimokata K, Niwa T, Kanai Y, Endou H.; ''Molecular identification of a renal urate anion exchanger that regulates blood urate levels.''; PubMed Europe PMC Scholia
  90. Costello LC, Liu Y, Zou J, Franklin RB.; ''Evidence for a zinc uptake transporter in human prostate cancer cells which is regulated by prolactin and testosterone.''; PubMed Europe PMC Scholia
  91. Li M, Zhang Y, Liu Z, Bharadwaj U, Wang H, Wang X, Zhang S, Liuzzi JP, Chang SM, Cousins RJ, Fisher WE, Brunicardi FC, Logsdon CD, Chen C, Yao Q.; ''Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression.''; PubMed Europe PMC Scholia
  92. Huang L, Kirschke CP, Gitschier J.; ''Functional characterization of a novel mammalian zinc transporter, ZnT6.''; PubMed Europe PMC Scholia
  93. Sloan JL, Mager S.; ''Cloning and functional expression of a human Na(+) and Cl(-)-dependent neutral and cationic amino acid transporter B(0+).''; PubMed Europe PMC Scholia
  94. Schimanski LM, Drakesmith H, Merryweather-Clarke AT, Viprakasit V, Edwards JP, Sweetland E, Bastin JM, Cowley D, Chinthammitr Y, Robson KJ, Townsend AR.; ''In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations.''; PubMed Europe PMC Scholia
  95. Marini AM, Matassi G, Raynal V, André B, Cartron JP, Chérif-Zahar B.; ''The human Rhesus-associated RhAG protein and a kidney homologue promote ammonium transport in yeast.''; PubMed Europe PMC Scholia
  96. Vandenbergh DJ, Thompson MD, Cook EH, Bendahhou E, Nguyen T, Krasowski MD, Zarrabian D, Comings D, Sellers EM, Tyndale RF, George SR, O'Dowd BF, Uhl GR.; ''Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations.''; PubMed Europe PMC Scholia
  97. Nelson H, Mandiyan S, Nelson N.; ''Cloning of the human brain GABA transporter.''; PubMed Europe PMC Scholia
  98. Okuda T, Haga T.; ''Functional characterization of the human high-affinity choline transporter.''; PubMed Europe PMC Scholia
  99. Zhou B, Gitschier J.; ''hCTR1: a human gene for copper uptake identified by complementation in yeast.''; PubMed Europe PMC Scholia
  100. Wang K, Zhou B, Kuo YM, Zemansky J, Gitschier J.; ''A novel member of a zinc transporter family is defective in acrodermatitis enteropathica.''; PubMed Europe PMC Scholia
  101. Ekaratanawong S, Anzai N, Jutabha P, Miyazaki H, Noshiro R, Takeda M, Kanai Y, Sophasan S, Endou H.; ''Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules.''; PubMed Europe PMC Scholia
  102. Markovich D, Regeer RR, Kunzelmann K, Dawson PA.; ''Functional characterization and genomic organization of the human Na(+)-sulfate cotransporter hNaS2 gene (SLC13A4).''; PubMed Europe PMC Scholia
  103. Chimienti F, Devergnas S, Pattou F, Schuit F, Garcia-Cuenca R, Vandewalle B, Kerr-Conte J, Van Lommel L, Grunwald D, Favier A, Seve M.; ''In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion.''; PubMed Europe PMC Scholia
  104. Morris ME, Felmlee MA.; ''Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid.''; PubMed Europe PMC Scholia
  105. Sun W, Wu RR, van Poelje PD, Erion MD.; ''Isolation of a family of organic anion transporters from human liver and kidney.''; PubMed Europe PMC Scholia
  106. Olivès B, Martial S, Mattei MG, Matassi G, Rousselet G, Ripoche P, Cartron JP, Bailly P.; ''Molecular characterization of a new urea transporter in the human kidney.''; PubMed Europe PMC Scholia
  107. Desouki MM, Geradts J, Milon B, Franklin RB, Costello LC.; ''hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands.''; PubMed Europe PMC Scholia
  108. Koepsell H, Endou H.; ''The SLC22 drug transporter family.''; PubMed Europe PMC Scholia
  109. Yamada R, Tokuhiro S, Chang X, Yamamoto K.; ''SLC22A4 and RUNX1: identification of RA susceptible genes.''; PubMed Europe PMC Scholia
  110. Wakida N, Tuyen DG, Adachi M, Miyoshi T, Nonoguchi H, Oka T, Ueda O, Tazawa M, Kurihara S, Yoneta Y, Shimada H, Oda T, Kikuchi Y, Matsuo H, Hosoyamada M, Endou H, Otagiri M, Tomita K, Kitamura K.; ''Mutations in human urate transporter 1 gene in presecretory reabsorption defect type of familial renal hypouricemia.''; PubMed Europe PMC Scholia
  111. Lin X, Ma L, Fitzgerald RL, Ostlund RE.; ''Human sodium/inositol cotransporter 2 (SMIT2) transports inositols but not glucose in L6 cells.''; PubMed Europe PMC Scholia
  112. Pajor AM.; ''Molecular cloning and functional expression of a sodium-dicarboxylate cotransporter from human kidney.''; PubMed Europe PMC Scholia
  113. Tanihara Y, Masuda S, Sato T, Katsura T, Ogawa O, Inui K.; ''Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters.''; PubMed Europe PMC Scholia
  114. Gründemann D, Schechinger B, Rappold GA, Schömig E.; ''Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter.''; PubMed Europe PMC Scholia
  115. Küry S, Dréno B, Bézieau S, Giraudet S, Kharfi M, Kamoun R, Moisan JP.; ''Identification of SLC39A4, a gene involved in acrodermatitis enteropathica.''; PubMed Europe PMC Scholia
  116. Reid G, Wolff NA, Dautzenberg FM, Burckhardt G.; ''Cloning of a human renal p-aminohippurate transporter, hROAT1.''; PubMed Europe PMC Scholia
  117. Wang F, Kim BE, Petris MJ, Eide DJ.; ''The mammalian Zip5 protein is a zinc transporter that localizes to the basolateral surface of polarized cells.''; PubMed Europe PMC Scholia
  118. Besecker B, Bao S, Bohacova B, Papp A, Sadee W, Knoell DL.; ''The human zinc transporter SLC39A8 (Zip8) is critical in zinc-mediated cytoprotection in lung epithelia.''; PubMed Europe PMC Scholia
  119. Gaither LA, Eide DJ.; ''The human ZIP1 transporter mediates zinc uptake in human K562 erythroleukemia cells.''; PubMed Europe PMC Scholia
  120. Veyhl M, Keller T, Gorboulev V, Vernaleken A, Koepsell H.; ''RS1 (RSC1A1) regulates the exocytotic pathway of Na+-D-glucose cotransporter SGLT1.''; PubMed Europe PMC Scholia
  121. He L, Wang B, Hay EB, Nebert DW.; ''Discovery of ZIP transporters that participate in cadmium damage to testis and kidney.''; PubMed Europe PMC Scholia
  122. Goytain A, Quamme GA.; ''Identification and characterization of a novel mammalian Mg2+ transporter with channel-like properties.''; PubMed Europe PMC Scholia
  123. Peltekova VD, Wintle RF, Rubin LA, Amos CI, Huang Q, Gu X, Newman B, Van Oene M, Cescon D, Greenberg G, Griffiths AM, St George-Hyslop PH, Siminovitch KA.; ''Functional variants of OCTN cation transporter genes are associated with Crohn disease.''; PubMed Europe PMC Scholia
  124. Lioumi M, Ferguson CA, Sharpe PT, Freeman T, Marenholz I, Mischke D, Heizmann C, Ragoussis J.; ''Isolation and characterization of human and mouse ZIRTL, a member of the IRT1 family of transporters, mapping within the epidermal differentiation complex.''; PubMed Europe PMC Scholia
  125. Matskevitch I, Wagner CA, Stegen C, Bröer S, Noll B, Risler T, Kwon HM, Handler JS, Waldegger S, Busch AE, Lang F.; ''Functional characterization of the Betaine/gamma-aminobutyric acid transporter BGT-1 expressed in Xenopus oocytes.''; PubMed Europe PMC Scholia
  126. Lee J, Peña MM, Nose Y, Thiele DJ.; ''Biochemical characterization of the human copper transporter Ctr1.''; PubMed Europe PMC Scholia
  127. Shannon JR, Flattem NL, Jordan J, Jacob G, Black BK, Biaggioni I, Blakely RD, Robertson D.; ''Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency.''; PubMed Europe PMC Scholia
  128. Hosoyamada M, Sekine T, Kanai Y, Endou H.; ''Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney.''; PubMed Europe PMC Scholia
  129. Olives B, Neau P, Bailly P, Hediger MA, Rousselet G, Cartron JP, Ripoche P.; ''Cloning and functional expression of a urea transporter from human bone marrow cells.''; PubMed Europe PMC Scholia
  130. Han O, Kim EY.; ''Colocalization of ferroportin-1 with hephaestin on the basolateral membrane of human intestinal absorptive cells.''; PubMed Europe PMC Scholia
  131. Li M, Zhang Y, Bharadwaj U, Zhai QJ, Ahern CH, Fisher WE, Brunicardi FC, Logsdon CD, Chen C, Yao Q.; ''Down-regulation of ZIP4 by RNA interference inhibits pancreatic cancer growth and increases the survival of nude mice with pancreatic cancer xenografts.''; PubMed Europe PMC Scholia
  132. Kishi F.; ''Isolation and characterization of human Nramp cDNA.''; PubMed Europe PMC Scholia
  133. Kobayashi Y, Ohshiro N, Sakai R, Ohbayashi M, Kohyama N, Yamamoto T.; ''Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]).''; PubMed Europe PMC Scholia
  134. Tamai I, Ohashi R, Nezu J, Yabuuchi H, Oku A, Shimane M, Sai Y, Tsuji A.; ''Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2.''; PubMed Europe PMC Scholia
  135. Liu Z, Peng J, Mo R, Hui C, Huang CH.; ''Rh type B glycoprotein is a new member of the Rh superfamily and a putative ammonia transporter in mammals.''; PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
114951view16:47, 25 January 2021ReactomeTeamReactome version 75
113395view11:47, 2 November 2020ReactomeTeamReactome version 74
112600view15:57, 9 October 2020ReactomeTeamReactome version 73
101754view12:49, 5 November 2018EgonwCHEBI:29036 is the identifier for Cu2+
101516view11:38, 1 November 2018ReactomeTeamreactome version 66
101052view21:20, 31 October 2018ReactomeTeamreactome version 65
100583view19:53, 31 October 2018ReactomeTeamreactome version 64
100132view16:39, 31 October 2018ReactomeTeamreactome version 63
99682view15:08, 31 October 2018ReactomeTeamreactome version 62 (2nd attempt)
99274view12:45, 31 October 2018ReactomeTeamreactome version 62
94493view08:58, 14 September 2017MkutmonReactome release 61
86602view09:22, 11 July 2016ReactomeTeamreactome version 56
83132view10:06, 18 November 2015ReactomeTeamVersion54
81475view13:00, 21 August 2015ReactomeTeamVersion53
76949view08:22, 17 July 2014ReactomeTeamFixed remaining interactions
76654view12:02, 16 July 2014ReactomeTeamFixed remaining interactions
75983view10:04, 11 June 2014ReactomeTeamRe-fixing comment source
75686view11:01, 10 June 2014ReactomeTeamReactome 48 Update
75042view13:55, 8 May 2014AnweshaFixing comment source for displaying WikiPathways description
74686view08:45, 30 April 2014ReactomeTeamReactome46
45063view20:02, 6 October 2011KhanspersOntology Term : 'metal ion transport pathway' added !
45062view20:01, 6 October 2011KhanspersOntology Term : 'sugar transport pathway' added !
42150view22:00, 4 March 2011MaintBotAutomatic update
39961view05:58, 21 January 2011MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(S)-Lactate Metabolite422 (ChEBI)
2-Oxoglutarate Metabolite30915 (ChEBI)
2-oxoglutarate Metabolite30915 (ChEBI)
5-Hydroxytryptamine Metabolite28790 (ChEBI)
Biogenic amines

transported by VMAT1/2

MetaboliteREACT_20722 (Reactome)
Biogenic amines

transported by VMAT1/2

MetaboliteREACT_21050 (Reactome)
CHT ProteinQ9GZV3 (UniProt)
CTL1-5 UnknownREACT_20955 (Reactome)
Carnitine Metabolite17126 (ChEBI)
Carnitine transporters UnknownREACT_22929 (Reactome)
Chloride Metabolite17996 (ChEBI)
Choline Metabolite15354 (ChEBI)
Citrate Metabolite30769 (ChEBI)
Class I GLUTs UnknownREACT_20111 (Reactome)
Copper Metabolite28694 (ChEBI)
D-fructose Metabolite15824 (ChEBI)
DCT1 ProteinP49281 (UniProt)
Dicarboxylates

transported by NaDC1

MetaboliteREACT_20685 (Reactome)
Dicarboxylates

transported by NaDC1

MetaboliteREACT_21161 (Reactome)
Divalent metals

transported by NRAMP1

MetaboliteREACT_20962 (Reactome)
Divalent metals

transported by NRAMP1

MetaboliteREACT_21144 (Reactome)
Dopamine Metabolite18243 (ChEBI)
ETT ProteinQ9H015 (UniProt)
Ergothioneine Metabolite4828 (ChEBI)
GABA Metabolite16865 (ChEBI)
GLUT2 tetramer ComplexREACT_8747 (Reactome)
GLUT5 ProteinP22732 (UniProt)
GLUT6/8/10/1

2

UnknownREACT_20110 (Reactome)
GLUT7/11 UnknownREACT_19472 (Reactome)
GLUT9 ProteinQ9NRM0 (UniProt)
GLYT UnknownREACT_21204 (Reactome)
Glycine Metabolite15428 (ChEBI)
H+ Metabolite15378 (ChEBI)
Inositol Metabolite17268 (ChEBI)
Inositols transported

by SMIT2

MetaboliteREACT_19525 (Reactome)
Inositols transported

by SMIT2

MetaboliteREACT_19739 (Reactome)
L-Proline Metabolite17203 (ChEBI)
MATE substrates MetaboliteREACT_20849 (Reactome)
MATE substrates MetaboliteREACT_21070 (Reactome)
MATE1/2 UnknownREACT_20810 (Reactome)
MCT substrates MetaboliteREACT_20996 (Reactome)
MCT substrates MetaboliteREACT_21125 (Reactome)
MTP1:Ceruloplasmin

(copper complex)

ComplexREACT_24142 (Reactome)
MTP1:Hephaestin

(copper complex)

ComplexREACT_24553 (Reactome)
MagT1/2 UnknownREACT_20757 (Reactome)
Magnesium Metabolite18420 (ChEBI)
Monocarboxylate

transporters

UnknownREACT_21092 (Reactome)
NAT1 ProteinP23975 (UniProt)
NH4+ Metabolite28938 (ChEBI)
NRAMP1 ProteinP49279 (UniProt)
NaDC1 ProteinQ13183 (UniProt)
NaDC3 ProteinQ8WWT9 (UniProt)
NaS1 ProteinQ9BZW2 (UniProt)
NaS2 ProteinQ9UKG4 (UniProt)
Noradrenaline Metabolite18357 (ChEBI)
Noradrenaline uptake

transporter

ProteinO15244 (UniProt)
OAT1-3 UnknownREACT_22994 (Reactome)
OAT1-3 substrates MetaboliteREACT_22453 (Reactome)
OAT1-3 substrates MetaboliteREACT_23252 (Reactome)
OAT2/4 UnknownREACT_23320 (Reactome)
OAT2/4 sulfate

conjugate substrates

MetaboliteREACT_22525 (Reactome)
OAT2/4 sulfate

conjugate substrates

MetaboliteREACT_23389 (Reactome)
OCT1 ProteinO15245 (UniProt)
OCT1 substrates MetaboliteREACT_22807 (Reactome)
OCT1 substrates MetaboliteREACT_23354 (Reactome)
OCT2 substrates MetaboliteREACT_22491 (Reactome)
OCT2 substrates MetaboliteREACT_23290 (Reactome)
OCT3 ProteinO75751 (UniProt)
OCT3 substrates MetaboliteREACT_22507 (Reactome)
OCT3 substrates MetaboliteREACT_22750 (Reactome)
ORCTL2 ProteinQ96BI1 (UniProt)
ORCTL2 substrates MetaboliteREACT_22882 (Reactome)
ORCTL2 substrates MetaboliteREACT_23364 (Reactome)
PROT ProteinQ99884 (UniProt)
Proton myo-inositol

cotransporter

ProteinQ96QE2 (UniProt)
RHAG ProteinQ02094 (UniProt)
RHBG ProteinQ9H310 (UniProt)
RHCG ProteinQ9UBD6 (UniProt)
SGLT1 ProteinP13866 (UniProt)
SGLT2 ProteinP31639 (UniProt)
SGLT4 ProteinQ2M3M2 (UniProt)
SLC6A GABA

transporters

UnknownREACT_20690 (Reactome)
SLC6A12 ProteinP48065 (UniProt)
SLC6A14 ProteinQ9UN76 (UniProt)
SLC6A15 ProteinQ9H2J7 (UniProt)
SLC6A18 ProteinQ96N87 (UniProt)
SLC6A19 ProteinQ695T7 (UniProt)
SLC6A20 ProteinQ9NP91 (UniProt)
SLC6A6 ProteinP31641 (UniProt)
SMIT ProteinP53794 (UniProt)
SMIT2 ProteinQ8WWX8 (UniProt)
SOAT ProteinQ3KNW5 (UniProt)
Serotonin Metabolite28790 (ChEBI)
Sodium dependent

Serotonin transporter

UnknownREACT_15766 (Reactome)
Sodium dpendent

Dopamine transporter

ProteinQ01959 (UniProt)
Solute carrier family

13 member 5

ProteinQ86YT5 (UniProt)
Succinate Metabolite15741 (ChEBI)
URAT1 ProteinQ96S37 (UniProt)
Urate Metabolite17775 (ChEBI)
Urea Metabolite16199 (ChEBI)
Urea transporters UnknownREACT_20946 (Reactome)
VMAT1/

2

UnknownREACT_21239 (Reactome)
ZIP6/ZIP14 UnknownREACT_21222 (Reactome)
ZIP7 ProteinQ92504 (UniProt)
ZIP8 ProteinQ9C0K1 (UniProt)
Zinc 2+ Metabolite29105 (ChEBI)
Zn++ Metabolite29105 (ChEBI)
ZnT1 ProteinQ9Y6M5 (UniProt)
ZnT2 ProteinQ9BRI3 (UniProt)
ZnT3 ProteinQ99726 (UniProt)
ZnT5 ProteinQ8TAD4 (UniProt)
ZnT6 ProteinQ6NXT4 (UniProt)
ZnT7 ProteinQ8NEW0 (UniProt)
ZnT8 ProteinQ8IWU4 (UniProt)
alpha-D-glucose Metabolite17925 (ChEBI)
compounds

transported by GLUT9

MetaboliteREACT_19454 (Reactome)
compounds

transported by GLUT9

MetaboliteREACT_19915 (Reactome)
fructose, galactose,

glucose

MetaboliteREACT_9596 (Reactome)
fructose, galactose,

glucose

MetaboliteREACT_9838 (Reactome)
galactose, glucose MetaboliteREACT_9575 (Reactome)
galactose, glucose MetaboliteREACT_9887 (Reactome)
glycine Metabolite15428 (ChEBI)
hCTR1 ProteinO15431 (UniProt)
hZIP1-4 UnknownREACT_20986 (Reactome)
hZIP10 ProteinQ9ULF5 (UniProt)
hZIP5 ProteinQ6ZMH5 (UniProt)
hexoses transported

by GLUT7/11

MetaboliteREACT_19505 (Reactome)
hexoses transported

by GLUT7/11

MetaboliteREACT_20174 (Reactome)
hexoses transported

by SGLT4

MetaboliteREACT_19903 (Reactome)
hexoses transported

by SGLT4

MetaboliteREACT_19933 (Reactome)
inorganic sulfate Metabolite16189 (ChEBI)
iron (3+) Metabolite29034 (ChEBI)
iron (ferrous) Metabolite18248 (ChEBI)
ligands of SLC6A12

(BGT-1)

MetaboliteREACT_14225 (Reactome)
ligands of SLC6A12

(BGT-1)

MetaboliteREACT_14644 (Reactome)
ligands of SLC6A14 MetaboliteREACT_15161 (Reactome)
ligands of SLC6A14 MetaboliteREACT_15206 (Reactome)
ligands of SLC6A15 MetaboliteREACT_13883 (Reactome)
ligands of SLC6A15 MetaboliteREACT_14097 (Reactome)
ligands of SLC6A19 MetaboliteREACT_15160 (Reactome)
ligands of SLC6A19 MetaboliteREACT_15227 (Reactome)
ligands of SLC6A6 MetaboliteREACT_14486 (Reactome)
ligands of SLC6A6 MetaboliteREACT_14671 (Reactome)
sodium ion Metabolite29101 (ChEBI)
taurolithocholate

sulfate

Metabolite17864 (ChEBI)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1935"
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