Butyrate-induced histone acetylation (Homo sapiens)

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Description

Quality Tags

Ontology Terms

Bibliography

1. Donohoe DR, Collins LB, Wali A, Bigler R, Sun W, Bultman SJ; ''The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation.''; Mol Cell, 2012 PubMed Europe PMC Scholia
2. Davie JR; ''Inhibition of histone deacetylase activity by butyrate.''; J Nutr, 2003 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	141022	view	12:50, 2 November 2025	Eweitz	Standardize case
	123102	view	08:57, 3 July 2022	Egonw	Made two pathways clickable
	105116	view	13:51, 8 July 2019	DeSl	Changed ID for HDACs from Wikidata to InterPro
	102201	view	14:53, 9 December 2018	Egonw	Replaced Wikipedia with Wikidata identifiers.
	89148	view	21:58, 22 August 2016	Ariutta	Ontology Term : 'classic metabolic pathway' added !
	88590	view	19:35, 11 August 2016	Mkutmon	fix unconnected lines
	73980	view	11:32, 13 March 2014	MaintBot	Clarified what inhibits the HDACs.
	73979	view	11:30, 13 March 2014	MaintBot
	73978	view	11:23, 13 March 2014	MaintBot	Converted 'beta oxidaton' to a label.
	73977	view	11:14, 13 March 2014	MaintBot
	73976	view	11:09, 13 March 2014	MaintBot	More identifiers.
	73975	view	11:02, 13 March 2014	MaintBot	More identifiers and fixed AKT and ACL to be protein.
	73974	view	10:58, 13 March 2014	MaintBot	Used ChEBI instead of InChIs (for now)
	73973	view	10:47, 13 March 2014	MaintBot	Modified description
	69937	view	20:01, 11 July 2013	Mkutmon	fixed unconnected lines
	69009	view	17:46, 8 July 2013	MaintBot	Updated to 2013 gpml schema
	57918	view	20:38, 4 February 2013	MaintBot	Modified categories
	54005	view	10:13, 18 November 2012	Egonw	Completed the diagram
	54004	view	09:59, 18 November 2012	Egonw	Ensured all translocations are now MIM conversions (as suggested on the ML).
	53994	view	19:16, 17 November 2012	Egonw
	53993	view	18:03, 17 November 2012	Egonw	Added InChIs.
	53933	view	13:23, 16 November 2012	Egonw	Added reference and several interactions
	53932	view	13:15, 16 November 2012	Egonw	Added the core metabolites
	53931	view	13:01, 16 November 2012	Egonw	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
ACL	Metabolite
AKT	Metabolite
Acetyl CoA	Metabolite
Acetylated Histone	Complex
Butyrate	Metabolite
Citrate	Metabolite
Glucose	Metabolite
Lipid biosynthesis
TCA cycle	Pathway

Annotated Interactions

No annotated interactions