Nanoparticle triggered autophagic cell death (Homo sapiens)
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Description
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Ontology Terms
Bibliography
- Li C, Liu H, Sun Y, Wang H, Guo F, Rao S, Deng J, Zhang Y, Miao Y, Guo C, Meng J, Chen X, Li L, Li D, Xu H, Li B, Jiang C; ''PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway.''; J Mol Cell Biol, 2009 PubMed Europe PMC Scholia
- Liu HL, Zhang YL, Yang N, Zhang YX, Liu XQ, Li CG, Zhao Y, Wang YG, Zhang GG, Yang P, Guo F, Sun Y, Jiang CY; ''A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt-TSC2-mTOR signaling.''; Cell Death Dis, 2011 PubMed Europe PMC Scholia
- Andón FT, Fadeel B; ''Programmed Cell Death: Molecular Mechanisms and Implications for Safety Assessment of Nanomaterials.''; Acc Chem Res, 2012 PubMed Europe PMC Scholia
- Khan MI, Mohammad A, Patil G, Naqvi SA, Chauhan LK, Ahmad I; ''Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles.''; Biomaterials, 2012 PubMed Europe PMC Scholia
- Ma X, Wu Y, Jin S, Tian Y, Zhang X, Zhao Y, Yu L, Liang XJ; ''Gold nanoparticles induce autophagosome accumulation through size-dependent nanoparticle uptake and lysosome impairment.''; ACS Nano, 2011 PubMed Europe PMC Scholia
History
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DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
AMPK | GeneProduct | ||
IR | |||
Insulin | Protein | ||
Nanomaterial | |||
PI3k/AKT | GeneProduct | ||
TCS-1 | GeneProduct | ||
TCS-2 | GeneProduct | ||
ULK1/2 | GeneProduct | ||
mTORC1 |
Annotated Interactions
No annotated interactions