Glycolysis (Saccharomyces cerevisiae)

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pyruvateH+2-phosphoglycerate3-phosphoglycerateH+H2ONADdihydroxy-acetone-phosphateAmino AcidsH+fructose-1,6-bisphosphateglyceraldehyde-3-phosphatePhosphatephosphofructokinase Iglyceraldehyde 3-phosphate dehydrogenase 2triosphosphate isomeraseglucose-6-phosphate isomeraseenolasephosphoenolpyruvatepyruvate kinase 2glyceraldehyde 3-phosphate dehydrogenase 3NADHATPglucose-6-phosphateADPenolase: ERR23-phophsoglycerate kinasepyruvate kinase 1glyceraldehyde 3-phosphate dehydrogenase 1phosphoglycerate mutase 3fructose-6-phosphatefructose-bisphosphate aldolasephosphoglycerate mutase 1enolase: ERR13-phospho-D-glyceroyl-phosphateATPADPphosphopyruvate hydrataseATPADPphosphofructokinase IIenolase 1


Description

Many yeast and bacterial species ferment pyruvate to 2,3-butanediol via the intermediate, acetoin. Although acetoin is a flavorless compound, it is a precursor to some off-odor compounds, such as diacetyl, which can be unfavorable in beer and wine. Acetoin and 2,3-butanediol are both by-products of alcoholic fermentation by S. cerevisiae and other wine yeasts. Acetoin production during alcoholic fermentation depends on the yeast strain and other variables such as substrate and temperature (as reported in (CITS: [16535224])). Wine yeasts with high fermentation power generally produce low acetoin levels and large amounts of ethanol and higher alcohols (alcohols with more than 2 carbons) (as reported in (CITS: [16535224])). SOURCE: SGD pathways, http://pathway.yeastgenome.org/server.html

Comments

GenMAPP remarks 
Based on http://pathway.yeastgenome.org/biocyc/

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Bibliography

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History

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CompareRevisionActionTimeUserComment
135640view05:08, 8 October 2024KhanspersModified description
107251view14:34, 17 September 2019MaintBotChEBI identifier normalization
107014view13:47, 17 September 2019MaintBotHMDB identifier normalization
96373view09:41, 10 March 2018EgonwReplaced secondary ChEBI identifiers with primary identifiers.
94316view12:34, 1 September 2017Marvin M2Connected unconnected line
94177view13:32, 25 August 2017DeSlAdded identifiers for all metabolites, corrected some misconnected enzymes, gave all enzymes new IDs (previous ones did not link to anything)
94162view14:40, 24 August 2017DeSlChanged textlabels to metabolites, connected lines.
69832view14:54, 11 July 2013EgonwMarked a few DataNodes with CAS registry numbers as metabolites.
69648view20:38, 8 July 2013MaintBotUpdated to 2013 gpml schema
67311view10:35, 26 June 2013Christine ChichesterOntology Term : 'glycolysis pathway' added !
41887view04:53, 2 March 2011MaintBotRemoved redundant pathway information and comments
36613view22:30, 9 April 2010MaintBotDescription and bibliography added from SGD
21211view11:31, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:Glycolysis]] moved to [[Pathway:WP253]]: Moved to stable identifier
12736view08:00, 17 May 2008MaintBotautomated metabolite conversion
8765view14:08, 7 January 2008MaintBotAdded to category $category
8763view14:08, 7 January 2008J.HeckmanUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
3-phophsoglycerate kinaseGeneProductS000000605 (SGD)
3-phospho-D-glyceroyl-phosphateMetabolite38168-82-0 (CAS)
ADPMetabolite58-64-0 (CAS)
ATPMetabolite1927-31-7 (CAS)
NADHMetabolite53-84-9 (CAS)
PhosphateMetabolite14265-44-2 (CAS)
enolase 1GeneProductS000003486 (SGD)
enolase: ERR1GeneProductS000005920 (SGD)
enolase: ERR2GeneProductS000006202 (SGD)
enolaseGeneProductS000001217 (SGD)
fructose-6-phosphateMetabolite643-13-0 (CAS)
fructose-bisphosphate aldolaseGeneProductS000001543 (SGD)
glucose-6-phosphate isomeraseGeneProductS000000400 (SGD)
glucose-6-phosphateMetabolite59-56-3 (CAS)
glyceraldehyde 3-phosphate dehydrogenase 1GeneProductS000003588 (SGD)
glyceraldehyde 3-phosphate dehydrogenase 2GeneProductS000003769 (SGD)
glyceraldehyde 3-phosphate dehydrogenase 3GeneProductS000003424 (SGD)
glyceraldehyde-3-phosphateMetabolite591-57-1 (CAS)
phosphoenolpyruvateMetabolite138-08-9 (CAS)
phosphofructokinase IIGeneProductS000004818 (SGD)
phosphofructokinase IGeneProductS000003472 (SGD)
phosphoglycerate mutase 1GeneProductS000001635 (SGD)
phosphoglycerate mutase 3GeneProductS000005417 (SGD)
phosphopyruvate hydrataseGeneProductS000004942 (SGD)
pyruvate kinase 1GeneProductS000000036 (SGD)
pyruvate kinase 2GeneProductS000005874 (SGD)
triosphosphate isomeraseGeneProductS000002457 (SGD)

Annotated Interactions

No annotated interactions
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